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An outstanding “One Health” leading Educational Institution of Higher Learning - Overview - Tuesday, January 24, 2017

An outstanding “One Health” leading Educational Institution of Higher Learning - Overview

Iowa State University – College of Veterinary Medicine

SEE: https://vetmed.iastate.edu/research-grad-studies/centers-institutes-and-initiatives/one-health

 One Health

The Iowa State University College of Veterinary Medicine has a long history of engagement in One Health. The veterinary profession and related health professions interact with both people and animals; therefore, providing a critical intersection of health and wellness information, especially in the areas of zoonotic and infectious diseases, and safe animal-sourced food products.

The College supports research related to animal and human health, especially in the areas of disease prevention, and maintenance of secure and safe animal food products.

One Health is reflected in our College Mission Statement: The Iowa State University College of Veterinary Medicine is dedicated to the enhancement of the health and well-being of animals and human beings through excellence in education, research, professional practice and committed service to the State of Iowa, the nation and the world. And supported by the Iowa State University Mission: Create, share and apply knowledge to make Iowa and the world a better place.

Also, our mission is aligned with the American Veterinary Medical College One Health Initiative: One Health is the integrative effort of multiple disciplines working locally, nationally, and globally to attain optimal health for people, animals, and the environment.

The Iowa State College of Veterinary Medicine supports One Health in all our university land-grant missions of education, research, professional practice, and outreach. Our curriculum is presented by knowledgeable instructors in comparative animal and human medicine, and many specialties.  These efforts are in collaboration with many university, college, and industry partners. We have long standing collaborations to improve animal and human health with the Iowa Regents Universities, especially the University of Iowa Carver College of Medicine and College of Public Health, and the USDA National Centers for Animal Health in Ames, IA.

One Health Related Programs

Additional Resources for One Health

Notable One Health leaders and Publications...

Dr. Lisa K. Nolan, Dr. Stephen G. Juelsgaard Dean of Veterinary Medicine https://vetmed.iastate.edu/users/lknolan

Dr. Claire Andreasen, One Health Director https://vetmed.iastate.edu/one-health-professor-and-director

Dr. James A. Roth, Director at the Iowa state University Center for Food Security and Public Health https://vetmed.iastate.edu/one-health-speaker/dr-james-roth and National Academy of Medicine member https://nam.edu/national-academy-of-medicine-elects-79-new-members/  

Dr. Glenda Dvorak, Assistant Director at the Iowa state University Center for Food Security and Public Health https://www.onehealthcommission.org/documents/filelibrary/leadership/Dvorak_Bio_Feb_2014_C30CA1F5D6EA5.pdf

Dr. Charles O. Thoen, Professor, Department of Veterinary Microbiology and Preventive Medicine https://vetmed.iastate.edu/users/cthoen; author video and text entitled: "Tuberculosis in Animals and Humans: A One health Approach" in Education Portal of World Veterinary Association – 2016 http://wva.learning.education/searchOnlineTraining/#/training/162322.

ONE HEALTH TEXTBOOKS:

Zoonoses – Protecting People and Their Pets - 1st Edition (2013) http://www.cfsph.iastate.edu/Products/zoonoses-protecting-people-and-their-pets.php?lang=en

Zoonotic Tuberculosis: Mycobacterium bovis and Other Pathogenic Mycobacteria - 3rd Edition (2014) http://www.wiley.com/WileyCDA/WileyTitle/productCd-1118474295,subjectCd-LS50.html


Resilience against infectious disease: a One Health approach - Saturday, January 21, 2017

Resilience against infectious disease: a One Health approach  

A special issue of Transactions of the Royal Society of Tropical Medicine and Hygiene

Guest editors: David Heymann, MD; Jonathan Jay, JD MA; Richard Kock, MA VMB VMD MRCVS

Call for papers:

Recent crises, including the Ebola and Zika virus epidemics, have highlighted the need for a systems approach to responding more effectively to infectious disease emergence. Human health  systems cannot wait to detect the first human cases: the pathogens are evolving and emerging in a multitude of ways and due to various drivers, often appearing first in animal populations, with environmental changes introducing or amplifying risk. Prevention, therefore, requires attention to resilience in ecosystems, and when this breaks down, intervening earlier to mitigate the impact of environmental disruptions and detect warning signs of disease among animals before they emerge in people.

This special issue of Transactions of the Royal Society of Tropical Medicine & Hygiene explores how a One Health approach—addressing infectious disease through collaboration across the biomedical, veterinary and environmental health disciplines—can reduce our vulnerability. As a contribution to the emerging literature on resilience and public health, it considers how One Health capacities at the local, national and global level can (a) constitute an actionable prevention and  “early warning system” for infectious disease threats and (b) reduce new threats by monitoring and improving the health of ecosystems.

Authors will present:

  • novel empirical and theoretical work on (a) how ecological shifts and disruptions modify infectious disease risk and/or (b) the role of animals, as vectors and hosts, in human infectious disease outbreaks;

  • research and commentary on the costs and benefits of various policies to integrate human, veterinary and environmental health within systems to prevent, detect and respond to infectious diseases.

Types of articles will include: research article (up to 3500 words, with a 200 word structured abstract and 30-40 references), review paper (3500 words, 200 word unstructured abstract and up to 60 references) or commentary (a shorter opinion style piece, 1000 words, 100 word abstract and up to 10 references).

This issue particularly invites research relevant to low- and middle-income country settings and seeks regional diversity in the projects represented. For articles focused on policy solutions, interdisciplinary collaborations (representing at least two of the three major One Health disciplines) are particularly encouraged; the guest editors will help facilitate these collaborations, as necessary.  

The deadline for submissions will be 1 March 2017. Interested authors should please submit a pre-submission inquiry to Samantha.Warne@rstmh.org and jonjay@mail.harvard.edu with a brief description of their proposal (e.g. a draft abstract). Pre-submission inquiries received by 1 February will receive priority consideration.

Provided to the One Health Initiative website January 21, 2017 by:

Jonathan Jay, JD, MA

Doctoral (DrPH) candidate

Harvard Chan School of Public Health

jonjay@mail.harvard.edu

(617) 519-1581

 

Note: Dr. Heymann is a member of the One Health Initiative Autonomous pro bono Advisory Board http://www.onehealthinitiative.com/advBoard.php.


Reminder January to December 2016: “7 Prominent U.S. and international individual and organizational One Health Endorsements (multidisciplinary)” - Wednesday, January 18, 2017

Reminder January to December 2016: “7 Prominent U.S. and international individual and organizational One Health Endorsements (multidisciplinary)”

International Association of Risk Management in Medicine (IARMM) Endorses One Health Initiative – Posted One Health Initiative website NEWS Tuesday, January 05, 2016

SEE: http://www.onehealthinitiative.com/publications/OneHealth.pdf & http://www.onehealthinitiative.com/publications/CCF20160105_0001.pdf [w/Signature]

[U.S.] Sen. [Al] Franken Pushes Bill [National One Health Act Will Help Top Agencies Understand, prevent, and Respond to Animal Disease Outbreaks] to Establish National Plan for Fighting Diseases Like Zika & Ebola - March 4, 2016 - Friday, March 04, 2016

http://www.onehealthinitiative.com/news.php?query=Sen.+Franken+Pushes+Bill+to+Establish+National+Plan+for+Fighting+Diseases+Like+Zika+%26+Ebola

Major U.S. Company (US Biologic) Strongly Endorses One Health – Posted One Health Initiative website NEWS Tuesday, April 05, 2016

http://www.onehealthinitiative.com/publications/US%20BIOLOGIC%20-%20One%20Health%20Initiative%20Endorsement%20Letter%204%205%202016.pdf

http://www.onehealthinitiative.com/publications/US%20BIOLOGIC%20-%20One%20Health%20Technology%20Platform%204%204%202016.pdf

U.S. Congressman Recognizes One Health Approach!

June 6, 2016 – Congressman Morgan Griffith, representing Virginia’s 9th District (USA) recognized the importance of utilizing the principles involved in the One Health concept on his weekly E-newsletter today.  See http://morgangriffith.house.gov/news/documentsingle.aspx?DocumentID=398573  

GIDEON “The world’s premier global infectious diseases database” SUPPORTS ONE HEALTH – Posted One Health Initiative website NEWS Wednesday, July 20, 2016

http://www.onehealthinitiative.com/news.php?query=GIDEON+%93The+world%92s+premier+global+infectious+diseases+database%94+SUPPORTS+ONE+HEALTH+

New President of American Veterinary Medical Association (AVMA) Endorses One Health - August 10, 2016 - Thursday, August 11, 2016

http://www.onehealthinitiative.com/news.php?query=New+President+of+American+Veterinary+Medical+Association+%28AVMA%29+Endorses+One+Health+ (*Scroll down)

Special Advisor Minister to Prime Minister of Ethiopia Endorses One Health – Posted One Health Initiative website NEWS Saturday, December 31, 2016

See endorsement letter at http://www.onehealthinitiative.com/publications/One%20Health%20Endorsement%20Letter.pdf

*Note: On December 30, 2016, Dr. Laura H. Kahn [MD, MPH, MPP], a co-founder of the One Health Initiative team, received a One Health Endorsement letter from Dr. Tedros Adhanom Ghebreyesus https://en.wikipedia.org/wiki/Tedros_Adhanom, Minister and Special Advisor to the Prime Minister of Ethiopia.  Dr. Ghebreyesus has been endorsed by the African Union as a candidate for the Director General of the World Health Organization (WHO).


One Health Newsletter Volume 9, Issue 2 published January 12, 2017 - Saturday, January 14, 2017

See latest published One Health issue...

One Health Newsletter Volume 9, Issue 2  published January 12, 2017

http://media.news.health.ufl.edu/misc/egh/One%20Health%20Newsletter/OHNLVol9Issue2.pdf

or

via One Health Initiative website http://www.onehealthinitiative.com/newsletter.php  

 


New CDC Tool: Map of Investments to Combat Antimicrobial Resistance - January 2017 - Thursday, January 12, 2017

CDC

New CDC Tool: Map of Investments to Combat AR

Centers for Disease Control and Prevention (CDC) sent this bulletin at 01/12/2017 03:30 PM EST

 

January 2017

 

 

For complete notice, SEE: https://content.govdelivery.com/accounts/USCDC/bulletins/17ff533

What's New

One Health

 


State-by-State Fact Sheets Show CDC’s Work to Combat AR


Just released, a new tool shows CDC’s key investments to combat antibiotic resistance (AR) across the nation. 

The CDC AR Investment Map includes an interactive web app and printable state- and city-specific fact sheets describing CDC’s work to tackle AR using fiscal year 2016 funds. Use these fact sheets to see how CDC supports AR activities in your area. 

View funding amounts by state and activity, including investments in:

  • State and local public health partners to fight AR in healthcare facilities, the community, and food.
  • Innovations and investigations to implement new ways to prevent antibiotic-resistant infections and contain their spread.
  • Public health laboratories to boost state and local testing capacity and technology to detect and contain, support response to, and prevent AR threats nationwide.
 

Combating antibiotic resistance is a CDC priority. We must remain vigilant to address and contain this ongoing threat as demonstrated by this week’s publication in CDC’s Morbidity and Mortality Weekly (MMWR) report

With these investments and the AR Solutions Initiative, CDC, in partnership with health departments, academia, and healthcare, is transforming how the nation combats and slows antibiotic resistance at all levels. Working together we can stand up a full, faster response to protect Americans from this threat.

Combating antibiotic resistance is a CDC priority. We must remain vigilant to address and contain this ongoing threat as demonstrated by this week’s publication in CDC’s Morbidity and Mortality Weekly (MMWR) report

With these investments and the AR Solutions Initiative, CDC, in partnership with health departments, academia, and healthcare, is transforming how the nation combats and slows antibiotic resistance at all levels. Working together we can stand up a full, faster response to protect Americans from this threat.


Find updates about One Health, diseases spread between humans and animals, new infographics, and much more on our home page



A COGENT CASE FOR ‘ONE HEALTH’ IMPLEMENTATION...NOW January 2017! - Tuesday, January 10, 2017

 

cid:image001.jpg@01D25C25.21D22050                     

                      http://www.onehealthinitiative.com/

 

One Health is the collaborative efforts of multiple disciplines working locally, nationally, and globally to attain optimal health for people, animals, plants and our environment.

One Health implementation will help protect and/or save untold millions of lives in our generation and for those to come.

 

 Between animal and human medicine there are no dividing lines--nor should there be.”      Rudolf Virchow, MD (the father of cellular pathology)

 

January 2017 Editorial Commentary

One Health Initiative Autonomous pro bono Team:

Laura H. Kahn, MD, MPH, MPP ▪ Bruce Kaplan, DVM ▪ Thomas P. Monath, MD ▪ Lisa A. Conti, DVM, MPH

______________________________

 

In the prelude to World War II, Winston Churchill quoted Edwin James Milliken’s poem with the final line ‘Death is in charge of the clattering train!’, when he felt that the British parliament was not taking the prospect of a war against Adolph Hitler seriously enough.

 

“...Who is in charge of the clattering train?
The axles creak and the couplings strain,
and the pace is hot and the points are near,
and sleep hath deadened the driver's ear,
and the signals flash through the night in vain,
for death is in charge of the clattering train.”

 

A COGENT CASE FOR ‘ONE HEALTH’ IMPLEMENTATION...NOW January 2017!

 

The international community has begun to take the One Health approach seriously, especially during the early 21st century http://www.onehealthinitiative.com/publications/01%20Kahn%20et%20al%20%205-19%208Mar07.pdf; http://www.izs.it/vet_italiana/2009/45_1/45_1.htm; http://www.izs.it/vet_italiana/2009/45_3/377.pdf.  This clattering train has been on and off the rails for many decades.  Failure to recognize, accept and fully implement this concept worldwide continues to deter human, animal, and environmental health life protecting and lifesaving advances yet to be applied and/or discovered!  One glaring example of critical need is that of the existential antimicrobial resistance threat discussed by the World Health Organization (WHO) http://www.who.int/mediacentre/factsheets/fs194/en/ and elaborated upon in a recently published book on the subject “One Health and the Politics of Antimicrobial Resistance https://jhupbooks.press.jhu.edu/content/one-health-and-politics-antimicrobial-resistance. 

 

Over the decades and indeed centuries, there have been and continues to be a vocal significant number of altruistic visionary research minded health scientists and officials within and among the public health, global health, clinical health, i.e. comparative medicine and planetary environmental health communities as well as some international governmental and political leaders that have seen the light...and essentially adopted the One Health approach, e.g. see http://www.onehealthinitiative.com/supporters.php; 7 Prominent U.S. and international individual and organizational One Health Endorsements (multidisciplinary): Jan.- Dec. 2016 http://www.onehealthinitiative.com/news.php?query=7+Prominent+U.S.+and+international+individual+and+organizational+One+Health+Endorsements+%28multidisciplinary%29%3A+Jan.-+Dec.+2016+ and “34 Prominent U.S. and international individual and organizational One Health Endorsements (multidisciplinary) – June 2011 to December 2015” Endorsements (multidisciplinary) – June 2011 to December 2015”

 

http://www.onehealthinitiative.com/publications/One%20Health%20Endorsements%20June%202011%20to%20December%202015.pdf

 

“One Health” is the pivotal point of how human health, animal health and the environment are inextricably linked.  Moreover, it is a key insight into and methodology for advancing the well-being of humans, animals and all global health more expeditiously and efficaciously http://www.springerpub.com/global-population-health-and-well-being-in-the-21st-century-toward-new-paradigms-policy-and-practice.html.   Having the One Health approach and principles implemented worldwide is truly equivalent to saying the sun rises in the east and sets in the west.  An effort has begun to help “prepare society to create the world we need through ‘One Health education” http://www.seejph.com/index.php/seejph/article/view/122 and http://onehealthkansas.k-state.edu/outreach/52/k-12-education-and-public-outreach-resources.   Aside from all the millions of words and esoterica published by scientific academicians and theoreticians worldwide during the past decade, there has emerged some irrefutable hardcore ‘real-world’ evidentiary proofs established for centuries and recently.

 

The documented tip of this One Health approach iceberg http://www.onehealthinitiative.com/publications/ONE%20HEALTH%20a%20significant%20international%20public%20health%20comparative%20medicine%20OHI%20POSTING%20May%2013%202015.pdf:

 

“The One Health concept has been successfully applied to many clinical health and public health milieus during the 19th, 20th and early 21st centuries.  Some significant examples of clinical health advances through comparative medical/surgical endeavors occurred during the past centuries using the One Health approach, i.e. these include public health and comparative medicine issues such as Heart Disease, Cancer, Orthopedic Disease, Anesthesiology, Obesity, Parasitic Diseases, Tuberculosis, Global Infectious Disease, Influenza,  Human Hepatitis C virus, Tickborne Diseases, Food Safety, Hendra virus vaccine, Aspergillus felis, Immunizations (vaccinations), Lou Gehrig’s Disease,  Ebola, Antibiotic Use and Resistance, Staphylococcus resistant infections, Environmental health Policymaking, Crimean-Congo hemorrhagic fever viruses, Renderpest, Emergency/Disaster preparedness and many others.”

 

Vaccines against diseases transmitted from animals to humans: A one health paradigm

“This review focuses on the immunization of animals as a means of preventing human diseases (zoonoses). …”In simple terms, the idea is to develop vaccines that protect domestic animals and wildlife thereby establishing effective barriers against human infections.  Developing animal vaccines are less expensive and are less strictly regulated than are those for humans.  Hopefully a common sense One Health approach can go forward.
http://www.onehealthinitiative.com/publications/Thomas%20P.%20Monath,%20MD%20Sept%202013%20One%20Health%20Vaccine%20Article.pdf

 

Several available One Health textbooks in print http://www.onehealthinitiative.com/news.php?query=Four+Landmark+One+Health+Textbooks+of+the+early+21st+Century+ and http://www.springerpub.com/global-population-health-and-well-being-in-the-21st-century-toward-new-paradigms-policy-and-practice.html

 

Four current outstanding open-access One Health Journal options for publications http://www.onehealthinitiative.com/journals.php

 

MORE:

2nd Global Conference on One Health: the World Veterinary Association (WVA), World Medical Association (WMA), Japanese Medical Association (JMA) and Japanese Veterinary Medical Association (JVMA) – Posted One Health Initiative website NEWS Saturday, November 12, 2016

2nd Global Conference on One Health: the World Veterinary Association (WVA), World Medical Association (WMA), Japanese Medical Association (JMA) and Japanese Veterinary Medical Association (JVMA)

Held in Japan – November 10-11, 2016

“During the Closing Ceremony of the 2nd Global Conference on One Health, the World Veterinary Association (WVA), World Medical Association (WMA), Japanese Medical Association (JMA) and Japanese Veterinary Medical Association (JVMA) signed on the Memorandum of Fukuoka. The 4 associations agreed to move from the validation and recognition stage of the “One Health Concept”, to the practical implementation stage:

1. Physicians and veterinarians shall promote the exchange of information aimed at preventing zoonotic diseases and strengthening cooperative relationships, as well as to undertake further collaboration and cooperation aimed at creating a system for zoonosis research.
2. Physicians and veterinarians shall strengthen their cooperative relationships to ensure the responsible use of important antimicrobials in human and animal healthcare.
3. Physicians and veterinarians shall support activities for developing and improving human and veterinary medical education, including understanding the One Health concept and approach to One Health challenges.
4. Physicians and veterinarians shall promote mutual exchange and strengthen their cooperative relationships in order to resolve all issues related to the creation of a healthy and safe society
.

World Medical Journal – UN 2030 Sustainable Development Goals and One Health

 http://lab.arstubiedriba.lv/WMJ/vol62/december-2016/#page=44

 

SEE “One Health Umbrella” graphic http://www.onehealthinitiative.com/OneHealth2


7 Prominent U.S. and international individual and organizational One Health Endorsements (multidisciplinary): Jan.- Dec. 2016 - Sunday, January 08, 2017

7 Prominent U.S. and international individual and organizational One Health Endorsements (multidisciplinary): Jan.- Dec. 2016

International Association of Risk Management in Medicine (IARMM) Endorses One Health Initiative – Posted One Health Initiative website NEWS Tuesday, January 05, 2016

http://www.onehealthinitiative.com/news.php?query=International+Association+of+Risk+Management+in+Medicine+%28IARMM%29+Endorses+One+Health+Initiative+

 

[U.S.] Sen. [Al] Franken Pushes Bill [National One Health Act Will Help Top Agencies Understand, prevent, and Respond to Animal Disease Outbreaks] to Establish National Plan for Fighting Diseases Like Zika & Ebola - March 4, 2016 - Friday, March 04, 2016

http://www.onehealthinitiative.com/news.php?query=Sen.+Franken+Pushes+Bill+to+Establish+National+Plan+for+Fighting+Diseases+Like+Zika+%26+Ebola

 

Major U.S. Company (US Biologic) Strongly Endorses One Health – Posted One Health Initiative website NEWS Tuesday, April 05, 2016

http://www.onehealthinitiative.com/news.php?query=Major+U.S.+Company+%28US+Biologic%29+Strongly+Endorses+One+Health

 

U.S. Congressman Recognizes One Health Approach! – Posted One Health Initiative website NEWS Wednesday, June 08, 2016

http://www.onehealthinitiative.com/news.php?query=U.S.+Congressman+Recognizes+One+Health+Approach%21

 

GIDEON “The world’s premier global infectious diseases database” SUPPORTS ONE HEALTH – Posted One Health Initiative website NEWS Wednesday, July 20, 2016

http://www.onehealthinitiative.com/news.php?query=GIDEON+%93The+world%92s+premier+global+infectious+diseases+database%94+SUPPORTS+ONE+HEALTH+

 

New President of American Veterinary Medical Association (AVMA) Endorses One Health - August 10, 2016 - Thursday, August 11, 2016 http://www.onehealthinitiative.com/news.php?query=New+President+of+American+Veterinary+Medical+Association+%28AVMA%29+Endorses+One+Health+

 

Special Advisor Minister to Prime Minister of Ethiopia Endorses One Health – Posted One Health Initiative website NEWS Saturday, December 31, 2016

http://www.onehealthinitiative.com/news.php?query=Special+Advisor+Minister+to+Prime+Minister+of+Ethiopia+Endorses+One+Health+

 


Special Advisor Minister to Prime Minister of Ethiopia Endorses One Health - Saturday, December 31, 2016

Special Advisor Minister to Prime Minister of Ethiopia Endorses One Health

See endorsement letter at http://www.onehealthinitiative.com/publications/One%20Health%20Endorsement%20Letter.pdf

*Note: On December 30, 2016, Dr. Laura H. Kahn [MD, MPH, MPP], a co-founder of the One Health Initiative team, received a One Health Endorsement letter from Dr. Tedros Adhanom Ghebreyesus https://en.wikipedia.org/wiki/Tedros_Adhanom, Minister and Special Advisor to the Prime Minister of Ethiopia.  Dr. Ghebreyesus has been endorsed by the African Union as a candidate for the Director General of the World Health Organization (WHO).

 

“Dear colleagues,

In today’s increasingly interconnected world, public health emergencies can affect anyone, anywhere. The development of resilient and robust global and local health systems capable of preventing, detecting and responding to public health emergencies must therefore be a key priority. For these systems to be effective, it is critical to recognize that the health of people is connected to the health of animals and the environment.

The global journey towards a safer and healthier world will be realized if we encourage collaborative efforts of multiple sectors and disciplines working locally, nationally, and globally-to achieve the best health for people, animals, and our environment.

As a strong believer in the need for everyone to come together for a healthier world, it is my honor to express my support for the One Health Initiative and stand here as a champion of the “One Health” approach at all levels. A one health approach is not only the right thing to do but also it is the smartest investment to address the challenges of infectious disease.”

Tedros Adhanom Ghebreyesus (PhD)

[https://en.wikipedia.org/wiki/Tedros_Adhanom]

Minister, Special Advisor to Prime Minister of Ethiopia

African Union Endorsed Candidate for Director General of WHO


2nd World Veterinary Association/World Medical Association GLOBAL CONFERENCE ON ONE HEALTH – November 10 -11, 2016 - Friday, December 30, 2016

Posted One Health Initiative website Wednesday, December 21, 2016 http://www.onehealthinitiative.com/publications.php?query=2nd+World+Veterinary+Association%2FWorld+Medical+Association+GLOBAL+CONFERENCE+ON+ONE+HEALTH+%96+November+10+-11%2C+2016+

 

2nd World Veterinary Association/World Medical Association GLOBAL CONFERENCE ON ONE HEALTH – November 10 -11, 2016

 

Moving forward from One Health Concept to One Health Approach 10 -11th November 2016, Kitakyushu City, Fukuoka Prefecture, Japan

 

SEE complete Summary http://www.worldvet.org/uploads/docs/2gcoh_japan_summary_2016.pdf

 

The 2GCOH resulted in the historic signature on the Memorandum of Fukuoka by WVA, WMA, JMA and JMVA. The 4 associations agreed to move from the validation and recognition stage of the “One Health Concept”, to the practical implementation stage:

 

i. Physicians and veterinarians shall promote the exchange of information aimed at preventing zoonotic diseases and strengthening cooperative relationships, as well as to undertake further collaboration and cooperation aimed at creating a system for zoonosis research.

ii. Physicians and veterinarians shall strengthen their cooperative relationships to ensure the responsible use of important antimicrobials in human and animal healthcare.

iii. Physicians and veterinarians shall support activities for developing and improving human and veterinary medical education, including understanding the One Health concept and approach to One Health challenges.

iv. Physicians and veterinarians shall promote mutual exchange and strengthen their cooperative relationships in order to resolve all issues related to the creation of a healthy and safe society.

 

Following the successful 2GCOH, the WVA and WMA received a number of proposals from Veterinary and Medical Associations to hold the 3rd Global Conference on One Health in their countries showing their great interest to enhance the collaborations between the veterinarians and physicians to work together on One Health issues.”


Conquest of Ebola in Humans and Animals - December 23, 2016 - Friday, December 23, 2016

                     

                      http://www.onehealthinitiative.com/

 

One Health is the collaborative efforts of multiple disciplines working locally, nationally, and globally to attain optimal health for people, animals, plants and our environment.

One Health implementation will help protect and/or save untold millions of lives in our generation and for those to come.

 

 Between animal and human medicine there are no dividing lines--nor should there be.”      Rudolf Virchow, MD (the father of cellular pathology)

 

A significant One Health issue...

NOTE:  The Ebola virus vaccine topic has been widely disseminated in national and international news reports today and yesterday:

http://www.npr.org/sections/goatsandsoda/2016/12/22/506600875/first-ebola-vaccine-likely-to-stop-the-next-outbreak

 

http://www.huffingtonpost.com/entry/ebola-vaccine_us_585c664be4b0d9a59457e00d

https://www.bloomberg.com/news/articles/2016-12-23/ebola-vaccine-made-by-merck-protects-against-deadly-virus

http://www.bbc.com/news/world-africa-38414060

http://www.un.org/apps/news/story.asp?NewsID=55867#.WF2ICuQixPY

http://www.nytimes.com/2016/12/22/health/ebola-vaccine.html?_r=0  

 

Conquest of Ebola in Humans and Animals

Provided to the One Health Initiative website December 23, 2016 by:

*Thomas P. Monath, MD

Chief Scientific & Chief Operating Officer

BioProtection Systems/NewLink Genetics Corp.

94 Jackson Rd. Suite 108

Devens, MA 01434

Henao-Restrepo et al. report the final results of a large efficacy trial of a novel, live attenuated vaccine against Ebola conducted in 2015 in the Republic of Guinea (Lancet, Published online December 22, 2016 http://dx.doi.org/10.1016/S0140-6736(16)32621-6). A single inoculation of the vaccine proved 100% effective in preventing Ebola virus disease. The trial was conducted under the leadership of the World Health Organization, in difficult circumstances during the large West African epidemic underway at the time and utilized a ring vaccination strategy which is described in detail in the publication. The vaccine tested is a recombinant virus composed of vesicular stomatitis virus Indiana (VSV-I) in which the envelope glycoprotein of VSV has been replaced by the corresponding envelope protein of Zaire ebolavirus (ZEBOV). The use of VSV, a virus causing infection and disease in animals (cattle, horses, and pigs), as the backbone for construction of a human vaccine is certainly noteworthy in the context of One Health, although there are analogous examples (e.g. vaccinia). The recombinant VSV-ZEBOV vaccine (rVSV-ZEBOV) was originally developed by the Public Health Agency of Canada and then licensed to and further developed by NewLink Genetics Corp. In 2014 the technology was exclusively licensed by NewLink to Merck, which is advancing development towards regulatory approval in the next 1-2 years.

It is expected that the availability of this vaccine will lead to the rapid control of future outbreaks of Ebola virus disease so that horrific events like the West African epidemic (2013-16) which caused over 28,000 cases and 11,000 deaths, will never be seen again.

Ebola outbreaks arise when the virus spills over from primary or secondary wild animal hosts. Like other zoonoses this disease exemplifies many principles of One Health. The primary reservoir hosts of ebolavirus are fruit bats, and direct contact with these animals or with fomites contaminated by bats are a probable source of human infection. Fruit bats are valued as a food source and are hunted and sold as bushmeat. Other animals including chimpanzees, bonobos, gorillas, monkeys, forest antelope and porcupines may be secondarily infected, are also hunted as bushmeat, and serve as a source of human infections. It is a continuing challenge to educate local populations about the role of these animals in disease transmission when they are valued as food in subsistence economies.

The great apes are highly susceptible to ebolavirus and develop lethal infections similar to humans. Human outbreaks have been directly caused by transmission from ape carcasses contaminated with the virus. The great apes are already threatened by habitat loss and have a low reproductive rate, and ebolavirus further threatens their survival.  In 2003-2004 an epizootic of Zaire ebolavirus is believed to have killed over 90% of the western lowland gorillas in the Lossi Sanctuary and in Odzala-Kokoua National Park in the Republic of Congo (Brazzaville). By some estimates, over 50,000 great apes have died in ebolavirus outbreaks in Central Africa in the last 10-15 years. This is a concern for conservation in general, for ecotourism which supports local economies, and for public health.

Given the advances in vaccine development, an obvious question is: How to use vaccines to prevent disease and deaths in wild animals, particularly the great apes? The result could not only reduce the treat to these endangered species, but also potentially reduce the risk of virus transmission to humans. The problem is vaccine delivery rather than vaccine development. The rVSV-ZEBOV vaccine is safe and highly effective in preventing ebola in monkeys and almost certainly would be also safe and effective in apes. A non-replicating, recombinant virus-like particle vaccine was used successfully to immunize captive chimpanzees (Warfield KL et al., PNAS 2014;111:8873-6). Use of these injected vaccines in the wild might be limited to darting small numbers of habituated animals in reserves. Delivery of rVSV-ZEBOV in oral bait may be considered as the vaccine appears to work by the oral route in monkeys. More promising is recent work on recombinant cytomegaloviruses (CMV) expressing ebola glycoprotein (Marzi A et al. Sci Rep. 2016;6:21674). CMV is transmissible and causes persistent infections, so that once introduced the vaccine virus might spread within the ape population, thus avoiding the need to immunize individuals.

Now that the control of human Ebola virus disease appears to be close at hand through the use of a vaccine, extension to animal species affected by this disease is the next horizon. Reaching that goal will require close collaboration across the medical and veterinary fields, ecologists, conservation scientists, and others in the One Health community.

*Dr. Monath http://www.onehealthinitiative.com/publications/Tom%20Monath%20Biography%20January2014%20(2015%20update).pdf, a physician and eminent internationally recognized medical virologist, is a co-founder of the One Health Initiative Autonomous pro bono team and the One Health Initiative website www.onehealthinitiative.com.

 


 
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