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One Health in ACTION – 2nd Article in Tuberculosis Series - Human tuberculosis caused by Mycobacterium bovis in the United States, Latin America and the Caribbean - Monday, October 18, 2010

One Health in ACTION – 2nd Article in Tuberculosis Series


Human tuberculosis caused by Mycobacterium bovis in the United States, Latin America and the Caribbean


By de Kantor I N,  LoBue P A, Thoen C O.  [Dr. Isabel de Kantor is a PhD; Dr. Philip LoBue is a physician; and Dr. Charles Thoen is a veterinarian]


[Serialised article. Tuberculosis: a re-emerging disease in animals and humans. Number 3 in the series]

or directly to the pdf


Provided by:

Clare Pierard | Managing Editor
International Journal of Tuberculosis and Lung Disease (IJTLD)
International Union Against Tuberculosis and Lung Disease
68, boulevard Saint-Michel | 75006 Paris | France
Tel: (+33) 1 44 32 03 60 | Fax: (+33) 1 43 29 90 83 | |

One Health in ACTION: Significant New One Health Oriented “Infection, Ecology and Epidemiology Network (IEE)” Established in Sweden - 2010 - Wednesday, October 13, 2010

One Health in ACTION:


Significant New One Health Oriented “Infection, Ecology and Epidemiology Network (IEE)” Established in Sweden

Read More on Home page:

“Combating and controlling zoonotic infections effectively, requires an approach where researchers use the “One World – One Health” perspective. The purpose of the IEE network is to stimulate interdisciplinary projects resulting in increased knowledge of emergence, spread and effects of infectious disease on human, domestic animals and wildlife. … .”

Infection, Ecology and Epidemiology, IEE network is a Swedish national collaboration for researchers with interest in zoonotic infections. As a consequence, some of the information on this website can only be found in Swedish. We apologise for any inconvenience and kindly ask you to contact IEE if you have questions and comments. 



IEE is an integration concept including several universities and governmental organizations that wish to contribute to a sustainable intellectual platform where veterinarians, physicians, molecular biologists, ecologists and environmental chemists with an interest in zoonotic infections can interact and create synergies. The rationale is not to build up new laboratory facilities, but to use and collaborate within already established research structures.


Main partners

Uppsala University

National Veterinary Institute, SVA

Swedish Agricultural University, SLU

Linnaeus University, Kalmar


Founded: 2010


Physical location: SVA, Ulls väg 2A, 751 89 Uppsala, Sweden


Project Leader: Björn Olsen, MD, PhD professor in infectious disease at Uppsala University and senior physician at Uppsala Academic Hospital. Dr. Olsen is an ornithologist with an interest in the consequences of interactions between humans, domestic animals and wildlife.


Project coordinator: Lovisa Svensson, PhD, SVA/Uppsala University


Communication officer webb: Eva Haxton, MSci, Uppsala Academic Hospital



Information Provided by:

Lovisa Svensson, PhD
Project coordinator
Infection Ecology and Epidemiology network
Uppsala, Sweden

Footnote:  The One Health Initiative website team of Laura H. Kahn, MD, MPH, MPP, Bruce Kaplan, DVM, Thomas P. Monath, MD, and Jack Woodall, PhD strongly supports this new and exciting One Health program.   Our team works with IEE both collaboratively and via reciprocal website links: please see and One Health Initiative website NEWS Statistics  posted on the News page (scroll down).

One Health - 2010 AAVLD/USAHA Plenary Sessions - Nov 13 & 15 - Monday, October 11, 2010


November 11-17, 2010

United States Animal Health Association (USAHA)
114th Annual Meeting - Minneapolis, Minnesota (USA)

American Association of Veterinary Laboratory Diagnosticians (AAVLD)
53rd Annual Conference

For more information on AAVLD programs, please go to


One Health - 2010 AAVLD/USAHA Plenary Sessions


Saturday, 13 Nov 2010

AAVLD Plenary Session – 7:50 – 11:30 a.m.


One Health: Opportunities for Veterinary Diagnostic Laboratories


7:50 a.m.      Welcome – Craig Carter, DVM, PhD, AAVLD President-Elect 

8:00                  Keynote-- Human-Animal Medicine Title: How Do Laboratories Fit Into the Picture?

                          - Peter Rabinowitz, MD, MPH

8:30                  NBAF And Its Role In the Growing One Health Initiative

                          Cyril Gay, DVM, PhD

9:00                  What are the Challenges and Pitfalls to my Laboratory Participating in One Health?

                           Bruce Akey, MS, DVM

9:30                  Break

10:00                Valuing One Health:  Opportunities and Challenges for Veterinary Diagnostic Laboratories

                           Tammy Beckham, DVM, PhD

10:30                When/Where/How Veterinarians Can Build Bridges Between the Diagnostic Laboratory and the Local Health Community –

                           -Tanya Graham, DVM, DAVCP

11:00 a.m.        Walk the Talk: The Center for Excellence of Emerging & Zoonotic Animal Diseases (CEEZAD) and One Health –

                          -Juergen Richt, DVM, PhD                 


Monday, 15 Nov 2010  

USAHA/AAVLD Joint Plenary Session – 7:50 – 12:00 a.m.


One Health: One Way Street Or Are There Opportunities for Animal Agriculture?


7:50 a.m.          Welcome – Steve Halstead, DVM, MS USAHA President-Elect; Lonnie King, DVM, MS, MPA Moderator

8:00                  Keynote--One Medicine:  Its All Herd Health

                           Lisa  A. Conti, DVM, MPH

8:30                  Emerging Infectious Diseases:  The Case for Integrating 

                        Science, Medicine and Public Health

                            - Gary Simpson, MD, PhD, MPH

9:00                  Producer perspective on One Health: What are the implications of being a One Health Partner

                             - Mark Engle. DVM, MS

9:30                  Break

10:00                One Health and the Environment: Improving Health in a Wicked World

 - Katie Pelican, DVM, PhD

10:30                Global prospective of One Health: Are we missing opportunities?

- Mo Salman, DVM, MPVM, PhD 

11:00                Emerging Microbial Threats: Challenges and Opportunities at the Human-Animal-Ecosystem Interface 

                                -James M. Hughes, MD

11:30                One Health Discussion and Q&A Panel             


Provided by:


Dr. Craig N. Carter

Director & Professor, Epidemiology

Livestock Disease Diagnostic Center

Department of Veterinary Science

Colleges of Agriculture & Public Health

University of Kentucky

1490 Bull Lea Rd.

Lexington, KY  40511

Press Release (received October 6, 2010): Agricultural Science and Politics - Thursday, October 07, 2010

Press Release (received October 6, 2010):

Agricultural Science and Politics

October 5, 2010—Dr. Juergen A. Richt [DVM, PhD], Kansas State University Regents Distinguished Professor and Director of CEEZAD, (Center of Excellence for Emerging and Zoonotic Animal Diseases), speaking at the Farm Foundation Conference on September 24, 2010, “Zoonoses: Understanding the Animal Agriculture and Human Health Connection” in Washington, DC, set out the links between politics, One Health and communication. He emphasized that “the search for the public health of the nation is a political pursuit, because we are competing with other policy objectives, other priorities and many special interests.” “We must affirm,” he said, “the relevance of politics in a democratic society and communicate with politicians in their hopes, agendas and concerns, even if their primary concern appears at times to be re-elected. I believe that it is our task to convince the politicians that if they want to be re-elected they need to support us in our pursuit to improve public health.”


In striving to achieve this goal of sound public health, Dr. Richt noted that “it is essential to unite human and veterinary medicine with ecological health, in a commitment to ‘One Health—One Medicine—One Environment.’ If we try to protect people without protecting animals and the environment, the result will be that people, animals and the environment will all suffer needlessly. Therefore, we need to support the One Health Initiative that seeks to unify human and veterinary medicine.” However, he noted that even with an awareness of the importance of politics and One Health, it was essential “to learn to be effective communicators to achieve our policy objectives.” 


Intriguingly, Dr. Richt suggested that “the closer you get to a brick wall, the better you can see the door in that wall. The brick wall is our own limitations; and the door in that brick wall is not always open, because it is a swinging door that is moving us back and forth from scientific issues to political issues. We all need to take the opportunity to move through that swinging door at the appropriate time on the appropriate issues.”


Dr. Richt concluded that, “whether our primary concern is scientific, agricultural, veterinary medicine, public health, ecohealth or political, we can all learn to communicate effectively, with both our friends and those who think they are our enemies. If we fail to communicate, we fail as scientists.”


For further information, please contact Karinne Cortes or 785-532-2793


Breast Cancer Awareness Month This October - One Health in ACTION: Human Breast Cancer Comparative Medicine Research Advances at MD Anderson Cancer Center - Wednesday, October 06, 2010

Breast Cancer Awareness Month This October


This previous News item is how “One Health” comparative medicine has advanced critical scientific knowledge about Breast Cancer:  think of what full One Health implementation and institutionalization could achieve!


One Health in ACTION: Human Breast Cancer Comparative Medicine Research Advances at MD Anderson Cancer Center - Friday, September 17, 2010

One Health in ACTION: Human Breast Cancer Comparative Medicine Research Advances at MD Anderson Cancer Center

 Physicians, PhDs, and Veterinarians working collaboratively and synergistically

 Department of Veterinary Sciences, Michale E. Keeling Center for Comparative Medicine and Research, The University of Texas

  Provided September 13, 2010 by:

 Christian R. Abee, DVM, MS, DACLAM
Doctor R. Lee Clark Professor and Chair
Department of Veterinary Sciences
Director, Michale E. Keeling Center for Comparative Medicine and Research
University of Texas MD Anderson Cancer Center
Bastrop, TX 78602

Telephone: (512) 321-3991 begin_of_the_skype_highlighting              (512) 321-3991      end_of_the_skype_highlighting


Research at the Keeling Center has led to discovery of new breast cancer therapeutic monoclonal antibodies, and the development of early breast cancer tests based on the antibodies.  These antibodies were discovered in the laboratory of Keeling Center investigator Dr. Feng Wang-Johanning [MD, PhD] and her Keeling Center collaborator, Dr. Gary Johanning [PhD].  The monoclonal antibodies are directed against an ancient retrovirus that originated outside the human body as a remnant of an exogenous retrovirus, and subsequently became incorporated into the genome of primates millions of years ago.  This retrovirus, termed human endogenous retrovirus (HERV), currently resides in the genome of all humans. 


Dr. Wang-Johanning and Dr. Johanning are focusing their studies on one highly active subgroup of HERV, HERV type K.  HERV-K is not usually expressed in normal, non-cancer cells, but they found that its expression re-emerges in human breast cancer, making it a good target for antibody therapy.  Dr. Wang-Johanning’s major research discovery to date is that monoclonal and single chain antibodies against HERV-K are effective in inhibiting breast cancer cell proliferation and inducing cell cycle arrest and apoptosis, both in vitro and in vivo.  Pivotal studies in immunodeficient mice demonstrated that tumor sizes were significantly reduced, and onset of tumorigenesis was significantly delayed, in antibody-treated mice bearing breast tumors. 


HERV-K is thus a novel antigen target for breast cancer, and Dr. Wang-Johanning’s pre-clinical studies provide compelling evidence that antibodies to HERV-K have the potential to be effective therapeutic agents for treating breast cancer.  She is currently developing humanized and human antibodies for clinical trials, aimed at translating her laboratory results to breast cancer patients.  Drs. Wang-Johanning and Johanning are hopeful that this antibody will rival the effectiveness of the well-known breast cancer therapeutic antibody Herceptin.  There is reason for their optimism, because while Herceptin is effective against only 25-30 percent of breast cancers, anti-HERV-K antibodies have the potential to be effective against almost all human breast cancers. 


The research of Dr. Wang-Johanning and collaborators has just taken an exciting turn.  They are taking advantage of the presence of HERV-K in breast cancer to develop early breast cancer tests.  These tests are based on detection of anti-HERV-K serum antibodies and viral RNA, and will be analogous to the PSA test that is widely used for prostate cancer screening.  There is a need for these tests, because currently there are no sensitive and specific serum tests for breast cancer.


These discoveries would not have been possible without “One Health” collaboration between Dr. Wang-Johanning’s group and investigators at the main M. D. Anderson Cancer Center campus in Houston.  Kelly Hunt, MD, breast cancer surgeon, provided breast cancer serum and tumor tissues for Dr. Wang-Johanning’s projects.  In addition, Stephan Ambs, PhD, National Cancer Institute, is collaborating with Dr. Wang-Johanning’s laboratory to assess the clinical significance of elevated HERV-K in breast cancer.  Bruce Bernacky, DVM at the Keeling Center, will also play a prominent role in upcoming studies with Dr. Wang-Johanning because he will provide access to primates for testing her antibodies prior to human clinical trials. 



Note: Please see the current issue of the Institute of Laboratory Animal Research (ILAR) Journal which contains “One Health: The Intersection of Humans, Animals and the Environment – Scientific Editor: James G. Fox, DVM, MS [2010 Volume 51, Number 3]


ILAR Journal and ILAR e-Journal
The National Academies
500 Fifth Street, NW
Washington, DC 20001
202-334-2590 begin_of_the_skype_highlighting              202-334-2590      end_of_the_skype_highlighting

202-334-1687 fax

Cameron Fletcher
, Managing Editor


One Health Initiative Symposium: Vaccination of Animals for Prevention and Control of Zoonotic Diseases - November 3-7, 2010 - Atlanta, GA (USA) - Tuesday, October 05, 2010

2nd REMINDER:  A Highly Significant …

One Health Initiative Symposium: Vaccination of Animals for Prevention and Control of Zoonotic Diseases


American Society for Tropical Medicine and Hygiene – 59th Annual Meeting -


November 3-7, 2010

Marriott Atlanta Marquis Hotel

Atlanta, Georgia (USA)


A symposium organized jointly by members of the ASTMH and the Society for Tropical Veterinary Medicine (STVM) deals with the broad subject of One Health.

  Marriott – Room A704, Thursday, November 4, 2010, 3:45 p.m. – 5:30 p.m. 



 The Symposium focuses on vaccines, considered the most cost effective means of disease prevention.  The role of vaccines in preventing the spread of disease from animals to humans will be explored.  Speakers will address exampls where vaccination in animal species (livestock, poultry and wildlife) for zoonotic disease agents is used or could be used in order to reduce the risk of human disease. 


Specific examples are drawn from important human diseases cause by viral agents of animals.  Speakers will address the potential for additional impact on disease risk reduction for selected vaccine-preventable diseases as well as opportunities for vaccine interventions.


Session Summary:


·                           Demonstrate concrete cases where the vaccination of wildlife, livestock and poultry is being used to reduce human disease.


·                           Provide a One Health forum for discussing the integration of approaches that can reduce disease risk in animals and people.


Symposium organizers:


Thomas P. Monath, MD, Chair – Partner, Kleiner Perkins Caufield & Byers and member, One Health Initiative Website team          

Bob H. Bokma, DVM, Co-Chair – United States Department of Agriculture-Animal Plant Health Inspection Service (USDA-APHIS)




Clarence J. Peters, MD University of Texas Medical Branch,  Galveston, TX (USA)

“Rift Valley fever: prevention of human disease outbreaks by vaccination of livestock”


Thomas Geisbert, PhD -  University of Texas Medical Branch,  Galveston, TX (USA)

“Progress in the development of vaccines against Ebola hemorrhagic fever”


Thomas E. Walton, DVM, PhD - USDA (retired),  Fort Collins, CO (USA)

“Venezuelan equine encephalomyelitis attenuated vaccine strain TC-83: successful application of an IND human vaccine to equines for control of major northern hemispheric epizootic and epidemic, 1969-1972.”


E. Paul H. Gibbs, BVSc, PhD - University of Florida, Gainesville, Fl (USA)

“The global eradication of rinderpest and its significance for “One World, One Health”.


Note: There will also be a One Health Initiative poster presentation by Jack Woodall, PhD, co-founder and associate editor of ProMED-mail.

                Friday, November 5, 2010 – Noon to 1:30 pm – Poster Session B



Maasai Vets [veterinarians] Carry Out Disease Surveillance of 86,000 Animals With Google Mobile Phones - Friday, October 01, 2010

News – London International Development Centre


Maasai Vets [veterinarians] Carry Out Disease Surveillance of 86,000 Animals With Google Mobile Phones

05 August 2010

"Mobile phones enable vets to upload information about diseases and vaccinations (shown by the coloured markers) to a project website. Credit: EpiCollect

Maasai vets in East Africa are using mobile phones to monitor diseases including anthrax and rabies as part of a partnership involving London-based academics. The Google mobile phones are helping to record how diseases are spreading in order to bolster preventative action, including vaccination campaigns. The new project in rural Kenya is led by the charity Vetaid and is backed by Google UK, which has donated 23 G1 Android devices to the surveillance effort. Data relating to more than 86,000 animals from 1,600 farms has already been logged via the mobile phones in the last month." ...


READ MORE about this extraordinary story:

Why the environment and environmental change matter to One Health - Thursday, September 23, 2010

Why the environment and environmental change matter to One Health


Submitted By: Meredith A. Barrett, Aaron H. Stoertz, Timothy A. Bouley


Human medicine and veterinary medicine demonstrate a long history of collaboration dating back to the 19th century.  Today, the One Health movement maintains this tradition, yet also increasingly incorporates environmental, public health, social science, public policy, and other non-medical scientific perspectives to address global health challenges.   Despite this shift towards multidisciplinarity, we feel that the emphasis on the environmental influences on human and animal health are not yet sufficiently represented in the movement. Though environmental issues are indeed finding a more prominent place in the One Health dialogue, they remain more on the fringes, likely as a result of the complexity in linking environmental changes to health. The following examples highlight the importance of the environment to One Health and illustrate how central One Health is and will be to global environmental change.

 It is essential to consider the environment in order to achieve optimal health for people and animals. In fact, addressing environmental factors affecting health is essentially a public health-oriented disease prevention strategy. Here are a few reasons why:

·          24% of the global burden of disease originate from environmental causes ( World Health Organization)

·          The potential health impacts of climate change will be broad and significant, including: heat and cold effects; wind, storms and floods; drought, nutrition and food security; food safety and disease; water and disease; air quality and disease; allergens and disease; vector and rodent-borne disease; occupational health; and UV radiation (Intergovernmental Panel on Climate Change)

·          More specifically, changes in temperature, precipitation and seasonality will influence infectious disease emergence, incidence and spread (e.g., dengue, malaria and cholera)

·          Other environmental drivers, such as land use changes and deforestation, also contribute to the loss of biodiversity and the spread of infectious diseases, as has been seen with malaria and Lyme disease

·          Human and animal well-being relies upon ecosystem services provided by the environment. Ecosystem services include supporting services (nutrient cycling, soil formation, primary production), regulating services (climate and flood regulation, disease buffering, water purification), provisioning services (food, water, fuel) and cultural services (aesthetic, spiritual, mental health) that make the persistence of human and animal life possible.  (See Figure 1 from the Millennium Ecosystem Assessment)

·          Many of these ecosystem services rely upon the maintenance of biodiversity (including species, ecosystems, populations and genes), which makes  possible the growth of food, healthy diets,  the development of new medicines, and the regulation of the emergence of infectious diseases  

 Despite the importance of the environment to the preservation of human and animal well-being, we face increasing challenges to the maintenance of healthy ecosystems. Rapidly shifting human pressures and global environmental change—including examples such as climate change, land use change, desertification and biodiversity loss—could severely compromise the future well-being of humans and animals. The global human population is estimated to reach 7 billion within the next few years and will increase its need for land, food and energy. However, currently 60% of the essential ecosystem services of the planet are degraded or are under increasing threat. This loss, combined with the potential increased frequency of heat waves, storm events, and droughts as a result of climate change, have the potential to contribute to global crop failures, soil erosion and, ultimately, injuries, malnutrition and other negative health outcomes.

 Human, animal and ecosystem health are inextricably connected. We see the One Health approach as an essential perspective to approaching these challenges. Collaboration among human health, animal health, public health and environmental science professionals will be necessary to address challenges, design collaborative solutions and create co-beneficial health and environmental policies for our rapidly changing world. The One Health Initiative can lead the way in further incorporating environmental programming into their mission and bringing more environmental professionals into the One Health movement.

The One Health Initiative website team is interested in increasing the presence of environmental professionals in One Health.  We have begun to solicit new articles with an environmental focus for the One Health Newsletter  If you work in health and the environment, please send us an email to see if you might be able to contribute an article to the One Health Initiative website and/or the quarterly newsletter c/o Editor Help us spread knowledge about these ecosystem connections. 

Figure 1. Harmful effects of ecosystem change on human health (from the Millennium Ecosystem Assessment “Ecosystems and Human Well-being: Health Synthesis;”

[Permission granted to reproduce World Health Organization item/s September 23, 2010 by WHO, Dolores Campanario, Geneva,Switzerland.]

To learn more, the following websites hold a wealth of information:

·          Millennium Ecosystem Assessment


·          Center for Global Health and the Environment


·          Center for Sustainability and the Global Environment


·          The World Health Organization

o          Climate Change and Human Health studies:

o         Health and Environment Linkages project :

o         Environmental burden of disease:

·          Intergovernmental Panel on Climate Change, Fourth Assessment Report, 2007, Human Health Chapter


·          IUCN Ecosystems and Human Wellbeing


·          UNEP and WHO’s Libreville Declaration on Health and Environment collaboration


·          Cooperation on Health and Biodiversity (COHAB)


·          Convention on Biological Diversity (CBD)


·          Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES)



 Meredith A. Barrett is a PhD candidate in the University Program in Ecology at the Nicholas School of Environment at Duke University, Durham, North Carolina (USA).  She is working to identify health consequences of human development on lemur populations in Madagascar.  Ms. Barrett, along with Aaron Stoertz, coordinate the Global Health Working Group, a student-run interdisciplinary forum at Duke University dedicated to educating students about global health issues.

 Aaron Stoertz is pursuing his MSc in Global health at Duke Global Health Institute and has a certificate in epidemiology from the University of North Carolina’s Gillings School of Global Public Health.  Mr. Stoertz’s current focus is human resources for health and health are distribution in underprivileged communities and nations.

 Timothy Bouley is currently studying global health adaptation to climate change while pursuing degrees in medicine at Duke University and environmental change at Oxford University, United Kingdom. 




Please see a notable One Health ProMED-mail posting on One Health Initiative Website ProMED Page - Tuesday, September 21, 2010.,F2400_P1001_PUB_MAIL_ID:1000,84924 


One Health Advocate/Supporter Website Promotes Global Cancer Awareness - Monday, September 20, 2010

One Health Advocate/Supporter Website Promotes Global Cancer Awareness


A recent global call to action is now promoted on the “Millennium Medicine Project Global Cancer Initiative” of the Humanitarian Resource Institute.  This website’s One Health advocacy was previously reported on a One Health Initiative website News item April 24, 2010 (scroll down). 

While scrolling down, please note the specific One Health Cancer News items highlighted, e.g. the first item under this announcement: “One Health in ACTION: Human Breast Cancer Comparative Medicine Research Advances at MD Anderson Cancer Center”. 

Two of many cancer references of interest:

1.       Head and Neck Program at Smilow Cancer Hospital and the Yale School of Medicine.

2.       Cancer - Key Facts: World Health Organization.

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