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Follow directives to avoid spreading COVID-19
pictouadvocate.com - Nova Scotia
Sunday, March 29, 2020.
Follow directives to avoid spreading COVID-19
The One Health initiative is a movement to forge co-equal, all-inclusive collaborations between physicians, osteopathic physicians, veterinarians, ...

 


Renin-Angiotensin System Blockers and the COVID-19 Pandemic At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers March 25, 2020 :
Saturday, March 28, 2020.

Renin-Angiotensin System Blockers and the COVID-19 Pandemic

At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers

March 25, 2020

https://www.ahajournals.org/doi/abs/10.1161/HYPERTENSIONAHA.120.15082 

 


Bats, Cats and Coronaviruses: What You Need to Know About COVID-19 (Livestream)
SIMONS FOUNDATION https://www.simonsfoundation.org/
Friday, March 27, 2020.

Bats, Cats and Coronaviruses: What You Need to Know About COVID-19 (Livestream)      

  • Speaker
  • Laura H. Kahn, M.D., M.P.H., M.P.P.  Princeton University (USA)
  • Dr. Kahn is a co-founder of the One Health Initiative team and website www.onehealthinitiative.com

Q&A: Laura Kahn *02 on COVIDís Spread and How We Defeat It
Princeton Alumni Weekly (USA)
Thursday, March 26, 2020.

Life of the Mind 

Published online March 25, 2020

World Health Organization (WHO) to fund Antimicrobial Resistance (AMR) research projects in 7 countries
Centers for Infectious Disease Research and Policy (University of Minnesota) March 24, 2020
Wednesday, March 25, 2020.

University of Minnesota

WHO to fund AMR research projects in 7 countries

“The World Health Organization's (WHO's) Special Programme for Research and Training in Tropical Diseases (TDR) announced late last week that 13 projects from 7 countries have been awarded funding for research on antimicrobial resistance (AMR). ...”

“... The projects emphasize a One Health approach to AMR, looking at the human, animal, and environmental drivers of drug-resistant infections. ...”

http://www.cidrap.umn.edu/news-perspective/2020/03/news-scan-mar-24-2020 


New study explores the benefits of a One Health approach to investigating antimicrobial resistance in Vietnam
Tuesday, March 24, 2020.

Anthony Fauci was ready for this. America was not.
The Washington Post - March 21, 2020
Saturday, March 21, 2020.

Anthony Fauci was ready for this. America was not.

https://www.washingtonpost.com/lifestyle/style/anthony-fauci-was-ready-for-this-america-was-not/2020/03/20/ee8ef3a6-69f6-11ea-b313-df458622c2cc_story.html

Note: Dr. Fauci supports the One Health concept/approach http://www.onehealthinitiative.com/news.php?query=Frequent+Media+Expert+Physician%2FPublic+Health%2FU.S.+Government+Spokesperson+for+Coronavirus+Epidemic+%28potential+Pandemic%29+Threat+Status+in+World+Supports+a+One+Health+Approach+%5BMarch+1%2C+2020+repeat%5D


Pertinent to current Pandemic COVID-19 containment reasoning
Community Mitigation Guidelines to Prevent Pandemic Influenza ó United States, 2017
Wednesday, March 18, 2020.

Pertinent to current Pandemic COVID-19 containment reasoning: Community Mitigation Guidelines to Prevent Pandemic Influenza — United States, 2017  https://www.cdc.gov/mmwr/volumes/66/rr/rr6601a1.htm#_blank


Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand
16 March 2020 Imperial College COVID-19 Response Team DOI: https://doi.org/10.25561/77482
Wednesday, March 18, 2020.

16 March 2020 Imperial College COVID-19 Response Team  DOI: https://doi.org/10.25561/77482 Page 1 of 20 

 Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand


 

 

https://www.imperial.ac.uk/media/imperial-college/medicine/sph/ide/gida-fellowships/Imperial-College-COVID19-NPI-modelling-16-03-2020.pdf

 Summary


 

 

 

The global impact of COVID-19 has been profound, and the public health threat it represents is the most serious seen in a respiratory virus since the 1918 H1N1 influenza pandemic. Here we present the results of epidemiological modelling which has informed policymaking in the UK and other countries in recent weeks. In the absence of a COVID-19 vaccine, we assess the potential role of a number of public health measures – so-called non-pharmaceutical interventions (NPIs) – aimed at reducing contact rates in the population and thereby reducing transmission of the virus. In the results presented here, we apply a previously published microsimulation model to two countries: the UK (Great Britain specifically) and the US. We conclude that the effectiveness of any one intervention in isolation is likely to be limited, requiring multiple interventions to be combined to have a substantial impact on transmission. 

Two fundamental strategies are possible: (a) mitigation, which focuses on slowing but not necessarily stopping epidemic spread – reducing peak healthcare demand while protecting those most at risk of severe disease from infection, and (b) suppression, which aims to reverse epidemic growth, reducing case numbers to low levels and maintaining that situation indefinitely. Each policy has major challenges. We find that that optimal mitigation policies (combining home isolation of suspect cases, home quarantine of those living in the same household as suspect cases, and social distancing of the elderly and others at most risk of severe disease) might reduce peak healthcare demand by 2/3 and deaths by half. However, the resulting mitigated epidemic would still likely result in hundreds of thousands of deaths and health systems (most notably intensive care units) being overwhelmed many times over. For countries able to achieve it, this leaves suppression as the preferred policy option. 

 

We show that in the UK and US context, suppression will minimally require a combination of social distancing of the entire population, home isolation of cases and household quarantine of their family members. This may need to be supplemented by school and university closures, though it should be recognised that such closures may have negative impacts on health systems due to increased absenteeism. The major challenge of suppression is that this type of intensive intervention package – or something equivalently effective at reducing transmission – will need to be maintained until a vaccine becomes available (potentially 18 months or more) – given that we predict that transmission will quickly rebound if interventions are relaxed. We show that intermittent social distancing – triggered by trends in disease surveillance – may allow interventions to be relaxed temporarily in relative short time windows, but measures will need to be reintroduced if or when case numbers rebound. Last, while experience in China and now South Korea show that suppression is possible in the short term, it remains to be seen whether it is possible long-term, and whether the social and economic costs of the interventions adopted thus far can be reduced.  

 

 

 


Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
The Lancet - March 9 2020
Friday, March 13, 2020.

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

 Published Online, The Lancet March 9, 2020 https://doi.org/10.1016/ S0140-6736(20)30566-3  

 Summary

Background Since December, 2019, Wuhan, China, has experienced an outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Epidemiological and clinical characteristics of patients with COVID-19 have been reported but risk factors for mortality and a detailed clinical course of illness, including viral shedding, have not been well described.

See: https://www.thelancet.com/pb-assets/Lancet/pdfs/S014067362305663.pdf


 
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