Another important One Health “silo” advancing human and animal medicine…   North Carolina (USA) State University – College of Veterinary Medicine has Dynamic One Health Program Between animal and human medicine there is no dividing line – nor should there be. The object is different but the experience obtained constitutes the basis of all medicine. - Rudolf Virchow (1821-1902) One Health—the concept describing the complex interrelationship involving ecosystem health and the health and well being of wildlife, domestic animals, and humans is the focus of the research and extension work of the College of Veterinary Medicine. The CVM and its centers, institutes, programs, and individual faculty members and students contribute to the health of the environment, animals, and people on the local, regional, national, and international level. One of several real life One Health examples: Better Understanding of human and animal “Cancers” through collaborative comparative medicine/translational research: Mission Statement The mission of the CCMTR is to promote scientific discovery and facilitate its clinical application to achieve the goal of improving the health of animals and humans. Translational research is patient-centric. The needs of the patients direct the emphasis of basic research, patient samples provide the critical resource to investigate the basis of disease, and patient participation in clinical studies is required to generate the evidence needed to apply new drugs, vaccines and technology to the broader patient population. Initiatives at the Center are designed to develop the multidisciplinary teams necessary to bring an idea from the lab to the patient. The Center is home to service cores that provide advanced technology, collect and store clinical patient samples, and perform clinical trials to validate new medical interventions. For more information contact the Center Director, Dr. Jorge Piedrahita: Oncology (Study of Cancer) The core concentrates on improving the understanding of the pathogenesis and treatment of cancer through collaborative research on induced and spontaneous models of cancer. Areas of focus include cancer genomics, cytogenetics, manipulation of tumor physiology, signaling and cell cycle control/differentiation, clinical diagnosis and treatment. For more information contact the core leader, Dr. Steve Suter Specific areas of research include: 1.      Cancer genomics/molecular cytogenetics of a variety of cancers of comparative significance (including linkage and mapping analysis, correlation with disease occurrence and outcome). 2.      Cell signaling/cell cycle control/differentiation. 3.      Tumor physiology (effects of intervention on physiologic parameters in tumors). 4.      Development and testing of novel therapeutics and validation of surrogate markers. 5.      Clinical diagnosis and treatment. As part of the In Search of Answers video series featuring Center researchers, Jonathan M. Horowitz, PhD  Dr. Horowitz provides enlightening discussions regarding oncology research and related areas: The animal/human connection. Tracking the role of the SP2 gene. Fighting cancer and healing wounds? NC States CVM and oncology research.”