A Book Review Opinion: “ONE HEALTH From AIDS to Zika” A product of Jones & Bartlett Learning, 5 Wall Street, Burlington, MA 01803, 978-443-5000, and SEE and     By Richard Riegelman, MD, MPH, PhD and Brenda Kirkwood, MPH, DrPH Dr. Riegelman, a physician, is Professor and Founding Dean of the Milken Institute School of Public Health at The George Washington University, Washington, DC. Dr. Kirkwood is Director of the Online Master of Public Health program at the University at Albany, SUNY, School of Public Health. She is also a Clinical Associate Professor in the Department of Health Policy, Management and Behavior at the University at Albany, SUNY, School of Public Health. This concise practicable ‘real world’ One Health booklet should be read by every longstanding One Health supporter/advocate who believes they fully understand the One Health concept.  It is well written and prepared.  As a model, it can help form and/or reform a basic appreciation for the widely recognized five or six journalism guidelines of What, Who, Where, When, Why and How.  Refreshingly, this is an instance where two sophisticated public health/epidemiology co-author educators wrote “in a nutshell”...absent unnecessary esoteric academic pedantries.  Its descriptive language demonstrates a brilliant simplicity suitable for teaching/exposing the concept to undergraduate [and graduate] students—for which it is primarily designed—as well as some visionaries who may have been immersed in the practice of utilizing a One Health approach for many years.  Having been a student and serious practitioner of One Health (formerly called One Medicine) since 1963-64, it rekindled my enthusiasm for educating the uninitiated along with those who think they know what One Health is all about...but, in fact, do not!  Indeed, to my chagrin, over the last 11 years of reading, writing about, editing vast quantities of One Health literature, and listening to talks by many One Health experts and being in direct contact with U.S. and internationally well known—and not so well known—One Health practitioner VIPs, I have encountered an occasional perception deficit or at least an inability to adequately define (or understand) the true essence of the concept.  This teaching guide book should help eliminate that problem in most (if not all) who read and study it carefully.  This includes knowledgeable laymen and professionals i.e., practicing physicians, veterinarians, nurses, other public health and clinical health research scientists and allied medical personnel. In particular I direct your attention to page 4, BOX 1 CONTROL OF ZOONOTIC DISEASES’ amusing yet pertinent historical annotation and page 6, Figure 2, the One Health Umbrella graphic  The graphic highlights the “Need for Broad [co-equal, multidisciplinary, interdisciplinary, transdisciplinary] Collaborations to Achieve the Goals of One Health” including more expeditious and efficacious global public health and comparative medicine big picture considerations.  One Health aspects pertaining to comparative medicine/translational medicine are not discussed further in this text.  Prior to reading this booklet, I asked a well-known highly respected One Health expert and One Health Initiative Team Advisory Board member, Dr. Bernadette Dunham [DVM, PhD], the former director of the Center for Veterinary Medicine, U.S. Food and Drug Administration, for her opinion and description of the text.  Incidentally, Dr. Dunham is acknowledged by the co-authors for being one of the two reviewers requested to help ‘ensure accuracy and clarity of the material.’  I cannot improve upon her initial brief response to my inquiry: “It is a very simple, 46 page booklet that provides a 101 for One Health type of approach for students being introduced to the One Health initiative. It is divided into three topic areas:   1.  Microbiological Influences on Health and Disease. The top 10 RNA viruses that cause infectious diseases are highlighted, as the title indicates from AIDS to Zika: AIDS, Chikungunya, Dengue, Ebola, Hantavirus, Influenza A, MERS, SARS, West Nile Virus, and Zika.  2. Ecosystem Health/Physical Environment.  How global movement transmits diseases; migration of people when impacted by droughts, disasters (floods, earthquakes, etc.); moving into previously uninhabited areas (forests, etc.) with increased exposure to new diseases; etc. Changes in agricultural practices (intensive farming; use of antibiotics); poor sanitation (cholera); building dams in certain areas + Schistosomiasis. Climate change impact on health.  3. Human - Animal Interactions.  Health benefits from our pets. Minimizing zoonotic disease transmission from pets. How to put One Health into Action.” In Summary: Implementing large scale distribution and recognition of this publication can help advance the One Health movement worldwide by articulating the essential usefulness of a paradigm shift for addressing the critical Global Public Health challenges our 21st century society faces in today’s hazardous and uncertain world. Bruce Kaplan, DVM Contents Manager/Editor One Health Initiative Website Co-Founder One Health Initiative team/website 4748 Hamlets Grove Drive Sarasota, Florida 34235 E-mail: Phone/fax: 941-351-5014 One Health Initiative Autonomous pro bono Team: Laura H. Kahn, MD, MPH, MPP ▪ Bruce Kaplan, DVM ▪ Thomas P. Monath, MD ▪ Lisa A. Conti, DVM, MPH