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One Health: Vision Loss Treatment for Dogs May Benefit Humans [“Comparative Medicine”]

August 31, 2018

“A novel gene therapy proven to halt vision loss in dogs is believed to have One Health potential. The scientists who developed the therapy, which treats a condition that causes blindness called autosomal dominant retinitis pigmentosa (adRP), are hopeful that their strategy may one day be used to delay or halt vision loss in people with the same disease. Retinitis pigmentosa, the most common inherited form of blindness, affects an estimate 60,000 to 100,000 people in the United States. ...”

 

American Veterinarian

August 30, 2018

One Health: Vision Loss Treatment for Dogs May Benefit Humans

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A novel gene therapy has been developed to treat one of the most common forms of retinitis pigmentosa, a disease that causes vision loss in both dogs and humans.

By Amanda Carrozza 

”A novel gene therapy proven to halt vision loss in dogs is believed to have One Health potential. The scientists who developed the therapy, which treats a condition that causes blindness called autosomal dominant retinitis pigmentosa (adRP), are hopeful that their strategy may one day be used to delay or halt vision loss in people with the same disease. Retinitis pigmentosa, the most common inherited form of blindness, affects an estimate 60,000 to 100,000 people in the United States.

“We’ve developed and shown proof-of-concept for a gene therapy for one of the most common forms of retinitis pigmentosa,” said William Beltran, DVM, PhD, a professor of ophthalmology at the University of Pennsylvania School of Veterinary Medicine and lead author of the study. The group’s study has been published in the Proceedings of the National Academy of Sciences.

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One Health to the Rescue: Intracranial Arteriovenous Malformation in a Dog Stem Cell-Derived Retinal Transplants May Improve Vision in Mice with End-Stage Retinal Degeneration ...”

Please ‘see’ complete article at https://www.americanveterinarian.com/news/one-health-vision-loss-treatment-for-dogs-may-benefit-humans

One of many ‘One Health in Action” examples: A term coined in 2007 http://www.izs.it/vet_italiana/2009/45_1/195.htm

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