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One Health drugs against parasitic vector borne diseases in Europe and beyond
 (OneHealthdrugs) aims at coordinating the discovery of drugs halting human and animal (H&A) vector-borne diseases (VBD) keeping with the principles of optimal profile for both organisms, increasing the quality and delivery technologies. 

Our Mission

OneHealthdrugs aims to coordinate the discovery of drugs that stop vector-borne infections in both human and veterinary settings according to the principles of the optimal profile for both organisms, increasing quality and reducing environmental impact.

COST Action ENTER – EU Foreign Policy Facing New RealitiesCOST Action Blog: Uniting forces for Neglected Tropical Diseases

*One Health in Action: Interprofessional collaboration & Education to eliminate Neglected Tropical Diseases (NTDs)& Antimicrobial Resistance (AMR) --June 18, 2024

 

*By Professor Rohini R. RoopnarineDVM, M. Phil, EdD, Dipl. AVOHS (Hon.), MRCVS

Member, National Academies of Practice ( Vet. Med), Course Director,  Veterinary Epidemiology & Public Health, School of Veterinary Medicine, True Blue campus, St. George’s University, Grenada, WI, Phone: +1 (473) 444-4175 ext. 3678, Email: rroopnarine@sgu.edu

 Bon Giorno distinguished PhD graduates and Professors in Medicinal chemistry. This conference and the COST One Health Drugs event, comes at a critical time when we are live in unpredictable times, facing emerging threats to global health from Zoonotic diseases. Zoonoses are defined as Diseases naturally transmitted between people & vertebrate non-human animals. or agents of animal origin such as SARS-CoV-2, the agent of COVID-19, Ebola & Highly Pathogenic Avian Influenza, now of huge concern in the US as we see cattle emerging as the latest reservoirs of HPAI. Global warming arising from climatic changes has led us to encounter health challenges of greater complexity , some resulting from expanding vector distribution and a concomitant rise in vector-borne diseases 

 Interprofessional collaboration is key to implementing OH as a tool for intercepting threats posed to human & planetary health. For decades, the focus has been on human health. But the reality is, human health is inextricably linked to animal health and the environment. Mosquitoes (malaria), ticks (Babesia) , Snails (Schistosomiasis) & Sandflies (Leishmaniasis) and other vectors carrying pathogens do not respect borders.They thrive in a delicate ecosystem, and the drugs created to combat them can have unintended consequences through both their environmental impact as well as unregulated useage. 

Your role & responsibilities as medicinal chemists, in the development  of new drugs, uniquely places you in a pivotal position in the global One Health agenda.

 The presentation today looks at…..title

SEE: RR June 18 Rome PPT.pptx - Google Slides https://docs.google.com/presentation/d/1PME4zioYBXn9OXrrD9u_OTDmDKtROhyZ/edit#slide=id.p1

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Commentary: 

Prof. Rohini Roopnarine gave an inspirational lecture on June 18th at the Paul Ehrlich&COST Action in Rome (https://medchem2024.help) to an audience of young researchers (PhD students) and academics with medicinal chemistry expertise. An educational view of the One Health concept and much more than this. How to dialogue with medicinal chemists in the One Health context? She could perfectly fit the purpose of the communication needs with the medicinal chemistry, a difficult task, and a non-obvious target. Under this light, Prof.Rohini made a successful effort to show real world examples of what an antiparasitic drug such as Ivermectin (active against different kinds of parasites to cure both humans and animal infections) can cause when overused and spread in the environment. The antimicrobials misuse implications in drug resistance development and those organizations and quadripartite alliance to manage the past disasters and the future events were clearly presented.  If I mention how the audience was captured by Rohini’s energy, it will not be enough. I only say about the enthusiastic comments and invitations received to bring her message to new events and future activities. Congratulations Rohini and thank you for accepting our invitation and being part of our OneHealthdrugs network!

Prof. Maria Paola Costi, PhD, Drug Discovery and Biotechnology Lab, Department of Life Science, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy, Office: +390592058579, Mobile: +393396559131

Left to Right: Prof. Stefano Alcaro, PhD, Prof. Maria Paola Costi (Chair), PhD and Prof. Rohini R. Roopnarine, DVM, M. Phil, EdD