An unheralded Significant One Health (One Medicine) approach… “Successful vaccines for naturally occurring protozoal diseases of animals should guide human vaccine research. A review of protozoal vaccines and their designs” Parasitology (2014), 141, 624–640. © Cambridge University Press 2014. The online version of this article is published within an Open Access environment subject to the conditions of the Creative Commons Attribution licence doi:10.1017/S0031182013002060   …“ONE MEDICINE [One Health] The concept of ‘One Medicine’ includes the beneficial flow of knowledge and techniques from human medicine to veterinary medicine, and from veterinary medicine to human medicine. However, because of the dominance of human medical research funding, the flow of information moves predominantly from human medicine to veterinary medicine. Human medicine is missing significant benefits that could be had by paying greater attention to veterinary knowledge and by supporting opportunities to investigate naturally occurring diseases of animals. This missed opportunity is vividly illustrated by the discordance between development of veterinary protozoal vaccines, of which there are many, and human protozoal vaccines, of which there are none. ” ...   SUMMARY “Effective vaccines are available for many protozoal diseases of animals, including vaccines for zoonotic pathogens and for several species of vector-transmitted apicomplexan haemoparasites. In comparison with human diseases, vaccine development for animals has practical advantages such as the ability to perform experiments in the natural host, the option to manufacture some vaccines in vivo, and lower safety requirements. Although it is proper for human vaccines to be held to higher standards, the enduring lack of vaccines for human protozoal diseases is difficult to reconcile with the comparatively immense amount of research funding. Common tactical problems of human protozoal vaccine research include reliance upon adapted rather than natural animal disease models, and an overwhelming emphasis on novel approaches that are usually attempted in replacement of rather than for improvement upon the types of designs used in effective veterinary vaccines. Currently, all effective protozoal vaccines for animals are predicated upon the ability to grow protozoal organisms. Because human protozoal vaccines need to be as effective as animal vaccines, researchers should benefit froma comparison of existing veterinary products and leading experimental vaccine designs. With this in mind, protozoal vaccines are here reviewed.”   Please read: Also, please note,MDSept2013OneHealthVaccineArticle.pdf