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A major public health issue...that requires implementation of One Health concept, i.e. a serious widespread collaborative, interdisciplinary approach!   U.S. Centers for Disease Control & Prevention   Antibiotic / Antimicrobial Resistance   Threat Report 2013 This report, Antibiotic resistance threats in the United States, 2013 gives a first-ever snapshot of the burden and threats posed by the antibiotic-resistant germs having the most impact on human health.  Each year in the United States, at least 2 million people become infected with bacteria that are resistant to antibiotics and at least 23,000 people die each year as a direct result of these infections. Many more people die from other conditions that were complicated by an antibiotic-resistant infection. Antibiotic-resistant infections can happen anywhere. Data show that most happen in the general community; however, most deaths related to antibiotic resistance happen in healthcare settings such as hospitals and nursing homes.   Please see: http://www.cdc.gov/drugresistance/threat-report-2013/