Antibiotic resistance: the emergence of plasmid-mediated colistin resistance enhances the need of a proactive one-health approach “For some years now, multi-resistant Gram-negative bacteria such as Escherichia coli or Klebsiella pneumoniae have been spreading globally, causing increasing difficulty in treating infectious diseases both in hospitals and the community at large. Of particular concern are carbapenemase-producing Enterobacteriaceae which are frequently resistant to nearly all antimicrobial drugs available.” ... To read complete article see attached HTM link: