U.S. Centers for Disease Control and Prevention Emerging Infectious Disease Journal – September 2011 Volume 17, Number 9 Canine Serology as Adjunct to Human Lyme Disease Surveillance Mead P, Goel R, Kugeler K. Canine serology as adjunct to human Lyme disease surveillance. Emerg Infect Dis [serial on the Internet]. 2011 Sep [date cited]. Abstract To better define areas of human Lyme disease risk, we compared US surveillance data with published data on the seroprevalence of Borrelia burgdorferi antibodies among domestic dogs. Canine seroprevalence >5% was a sensitive but nonspecific marker of human risk, whereas seroprevalence <1% was associated with minimal risk for human infection.