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Environmental amoebas came before animals as hosts to bacteria Citation: Strassmann JE, Shu L (2017) Ancient bacteria–amoeba relationships and pathogenic animal bacteria. PLoS Biol 15(5): e2002460. https://doi.org/10.1371/journal.pbio.2002460 http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2002460 Abstract Long before bacteria infected humans, they infected amoebas, which remain a potentially important reservoir for human disease. Diverse soil amoebas including Dictyostelium and Acanthamoeba can host intracellular bacteria. Though the internal environment of free-living amoebas is similar in many ways to that of mammalian macrophages, they differ in a number of important ways, including temperature. A new study in PLOS Biology by Taylor-Mulneix et al. demonstrates that Bordetella bronchiseptica has two different gene suites that are activated depending on whether the bacterium finds itself in a hot mammalian or cool amoeba host environment. This study specifically shows that B. bronchiseptica not only inhabits amoebas but can persist and multiply through the social stage of an amoeba host, Dictyostelium discoideum.
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History of the One Health Initiative team and website (April 2006 through September 2015) and the One Health Initiative website since October 1, 2008 … revised to June 2020 and again to date February 2021
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Vaccines for zoonoses: a One Health paradigm
SciTech Europa Quarterly (March 2018) – Issue 26
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SciTech Europa Vaccines for zoonoses: a one Health paradigm – Pages 227-229 (Read PDF) “One of the One Health Initiative team’s co-founders and leaders is an internationally-recognized eminent physician…
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