Important One Health example – Comparative Medicine Extreme Beta-Cell Deficiency in Pancreata of Dogs with Canine Diabetes * E-mail: Affiliation: McNair Medical Institute, Pediatric Diabetes and Endocrinology, Baylor College of Medicine, Texas Children’s Hospital, Houston, TX, United States of America ⨯ Published: June 9, 2015 PLOS One  DOI: 10.1371/journal.pone.0129809 Shields EJ, Lam CJ, Cox AR, Rankin MM, Van Winkle TJ, Hess RS, et al. (2015) Extreme Beta-Cell Deficiency in Pancreata of Dogs with Canine Diabetes. PLoS ONE 10(6): e0129809. doi:10.1371/journal.pone.0129809  “...In summary, our results advance the field by providing a precise quantitative analysis of islets within the pancreata of diabetic dogs. At previous studies have reported a qualitative loss of islets and β-cells in diabetic dogs [7, 17]. However, there is a notable gap in our knowledge of pancreas and islet morphometry within diabetic dogs. We hope that our results inform future studies to derive better therapies for this common and destructive disease of companion animals, and by extension advance therapies for human type 1 diabetes.” Also referred to in U.S. National Library of Medicine MedLinePlus piece, Wednesday, September 16, 2015