One Health Principles Needed for Ageing Research in Humans and Animals http://www.izs.it/vet_italiana/2011/47_3/47_3.htm “In these papers, I examine controversy over the nature of ageing. Central ideas include why post-reproductive life span is relatively common among animals, and implications for evaluating. Contentious debate revolves around whether ageing is a combined effect of life’s events on residuals of reproductive robustness, or whether ageing could be a purposeful product of natural selection. In my view, complexities of ageing might be understood by simultaneously considering the cell, the organism, and the population. The idea that events of post-reproductive life represent considerable investment of precious energy challenges some accepted precepts. I suggest that ageing and its investments may have evolved at least partly as a means of niche preservation for populations and species at multiple levels of life. It is clear that advancing knowledge and resolving questions and problems relative to ageing requires a One Health approach for human and animal species. The necessary knowledge evolution will occur only by greatly increasing the level of interdisciplinary research, and especially direct collaborations between research scientists and health care providers across disciplines.” Dennis F. Lawler, DVM Note: Dr. Lawler is a retired veterinarian currently residing in OFallon, Illinois (USA). He is a consultant in anatomic and clinical pathology for broad-scope genetics studies of the mammalian body plan, using the Portuguese Water Dog canine model, Project Georgie, the University of Utah, Salt Lake City (USA). Permission for the One Health Initiative website to post access to these three articles was graciously granted on September 22, 2011 by Gill Dilmitis, Associate Editor, firstname.lastname@example.org, Veterinaria Italiana Journal.