Shin B and Park W (2018) Zoonotic Diseases and Phytochemical Medicines for Microbial Infections in Veterinary Science: Current State and Future Perspective. Front. Vet. Sci. 5:166. doi: 10.3389/fvets.2018.00166 “...The health of humans and animals has been threatened by increasing resistance to antibiotics, environmental pollution, and the development of chronic diseases (1). It is necessary to understand and use the concept of One Health to effectively control and prevent diseases in the human–animal interface. The concept of One Health is currently advancing with the emergence and spread of epizootics, zoonoses, and epidemics, whereas the risks of pandemics have become an increasing critical challenge (2). Antimicrobial agents have seen general use in human and veterinary medicine for >50 years and have shown tremendous health benefits (3). However, the misuse and overuse of antibiotics generate selective evolutionary pressures that increase the chance of survival of antibiotic-resistant bacteria, which puts individuals at risk of becoming infected by drug-resistant bacteria (4). This development of antibiotic resistance renders the antimicrobial therapies ineffective, thus posing a serious public health threat. ...”