MEDICINA (Buenos Aires) 2016; 76: 159-165 - Journal Online: (Open-Access) ZOONOTIC TUBERCULOSIS. A COMPREHENSIVE ONE HEALTH APPROACH *CHARLES O. THOEN1, BRUCE KAPLAN2, TYLER C. THOEN3, MICHAEL J. GILSDORF4, JACK A. SHERE5 Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, 2One Health Initiative, Sarasota, Fla, 3Board Certification Internal Medicine, McFarland Clinic, Ames, IA, 4Former Director of the National Center for Animal Health Programs, United States Department of Agriculture, 5Deputy Administrator, Veterinary Services, Animal and Plant Health Inspection Services, United States Department of Agriculture, Washington, DC. USA Abstract: The objective of this report is to provide information on Mycobacterium tuberculosis complex infections in animals and in humans. Included is information on the susceptibility of different species as well as information on etiology, epidemiology, pathogenesis, diagnosis, prevention and control of this disease. The term One Health has been adopted to describe the unified human medical and veterinary interdisciplinary/mul­tidisciplinary collaborative approach to zoonoses and will be critical for future endeavors in the control of the global TB epidemic. This unified paradigm is ideally suited for control of bovine TB and many other international public health and clinical health issues. Sharing resources and increasing interaction between public health and veterinary medical scientists can raise awareness of ‘shared risk’ of bovine TB between humans and animals and, in resource-limited situations, can maximize use of existing infrastructure and reduce unnecessary duplication of effort in disease control programs. *Dr. Charles O. Thoen [DVM, PhD], an internationally recognized Tuberculosis expert, is the principal Co-editor of the One Health textbook, Zoonotic Tuberculosis: Mycobacterium bovis and Other Pathogenic Mycobacteria,subjectCd-LS50.html - 3rd Edition (2014) and immediate past president of the American Veterinary Epidemiology Society (AVES).  Dr. Thoen is also a longstanding One Health leader and supporter