One Health Publications

Infection Ecology and Epidemiology The One Health Journal (IEE)… How urbanization affects the epidemiology of emerging infectious diseases Carl-Johan Neiderud, MD, Section of Infectious Diseases, Department of Medical Sciences, Uppsala University, Uppsala, Sweden Neiderud C-J (2015) How urbanization affects the epidemiology of emerging infectious diseases. Infection Ecology and Epidemiology, 5: 27060 http://dx.doi.org/10.3402/iee.v5.27060 Abstract “The world is becoming more urban every day, and the process has been ongoing since the industrial revolution in the 18th century. The United Nations now estimates that 3.9 billion people live in urban centres. The rapid influx of residents is however not universal and the developed countries are already urban, but the big rise in urban population in the next 30 years is expected to be in Asia and Africa. Urbanization leads to many challenges for global health and the epidemiology of infectious diseases. New megacities can be incubators for new epidemics, and zoonotic diseases can spread in a more rapid manner and become worldwide threats. Adequate city planning and surveillance can be powerful tools to improve the global health and decrease the burden of communicable diseases.” Please read complete article http://www.infectionecologyandepidemiology.net/index.php/iee/article/view/27060

A One Health issue... Is a serious Emerging Disease Pathogen being under appreciated? A prominent and highly respected biomedical (comparative medicine) disease researcher says yes! *Edward Breitschwerdt, DVM, DACVIM, Professor, Internal Medicine Adjunct Professor of Medicine, Duke University Medical Center Phone: 919.513.8277 Fax: 919.513.6464 Email: ed_breitschwerdt@ncsu.edu - http://www.cvm.ncsu.edu/docs/personnel/breitschwerdt_ed.html “From my perspective, it is time for a Bartonella tipping point whereby this emerging pathogen is accorded a higher national (United States) and international research priorities.” Letter to the Editor of Parasites & Vectors Journal- Did Bartonella henselae contribute to the deaths of two veterinarians? Parasites & Vectors 2015, 8:317 doi:10.1186/s13071-015-0920-4 Please read http://www.parasitesandvectors.com/content/8/1/317 and for more information about the disease “Bartonellosis” see http://emedicine.medscape.com/article/213169-overview * Dr. Breitschwerdt, a veterinarian, is listed on the One Health Initiative website’s Supporters page http://www.onehealthinitiative.com/supporters.php.

The OIE unveils the online version of its publication World Animal Health The World Organisation for Animal Health (OIE) is placing online its publication World Animal Health, a unique compilation of information on the world situation relating to animal diseases, including those transmissible to humans, available to all and updated on a daily basis. Paris, 3 June 2015 – Published for over 30 years, World Animal Health provides an annual synthesis of information relating to at least the OIE’s 180 Member Countries, covering not only the animal diseases present on their respective territories, but also their relevant disease surveillance and control methods. It also provides data on animal populations and production figures. Previously available in hard copy and updated once a year, World Animal Health, in its new web-based format, will now give access to information that is updated throughout the year and can be extracted in the form of Excel tables and easily disseminated. The data contained in World Animal Heath are derived directly from the OIE World Animal Health System (WAHIS), which gathers information on the world situation relating to diseases of domestic and wild terrestrial and aquatic animals – including diseases transmissible to humans –, reported by OIE Member Countries as well as some non-member countries. The only compilation of its kind, World Animal Health presents a synthesis of the animal disease information contained in all the reports from countries received on a permanent basis by the OIE, once the information has been verified and validated by the OIE’s World Animal Health Information and Analysis Department. World Animal Health now makes it easier to consult and use the data made available via the online interface of WAHIS, which constitutes a comprehensive collection of the animal health data received and treated by the OIE. http://www.oie.int/en/for-the-media/press-releases/detail/article/the-oie-unveils-the-online-version-of-its-publication-world-animal-health/

Center for Excellence for Zoonotic and Animal Diseases (CEEZAD) - News & Press Release - June 11, 2015 Further Spread of Highly Pathogenic Avian Influenza: The Big Picture “Some 140 news outlets, including The International Business Times, The Times of India, Medical News Today in the United Kingdom and The Medical News in Australia, have now published information from the CEEZAD Press Release of May 26, 2015. ...” Please read complete article www.ceezad.org/about/news.html NOTE: CEEZAD recognizes the One Health concept http://www.ceezad.org/resources/links.html.

PLOS Neglected Tropical Diseases, Thursday 4 June 2015 What factors might have led to the emergence of Ebola in West Africa? June 4, 2015  DOI: 10.1371/journal.pntd.0003652 Abstract “An Ebola outbreak of unprecedented scope emerged in West Africa in December 2013 and presently continues unabated in the countries of Guinea, Sierra Leone, and Liberia. Ebola is not new to Africa, and outbreaks have been confirmed as far back as 1976. The current West African Ebola outbreak is the largest ever recorded and differs dramatically from prior outbreaks in its duration, number of people affected, and geographic extent. The emergence of this deadly disease in West Africa invites many questions, foremost among these: why now, and why in West Africa? Here, we review the sociological, ecological, and environmental drivers that might have influenced the emergence of Ebola in this region of Africa and its spread throughout the region. Containment of the West African Ebola outbreak is the most pressing, immediate need. A comprehensive assessment of the drivers of Ebola emergence and sustained human-to-human transmission is also needed in order to prepare other countries for importation or emergence of this disease. Such assessment includes identification of country-level protocols and interagency policies for outbreak detection and rapid response, increased understanding of cultural and traditional risk factors within and between nations, delivery of culturally embedded public health education, and regional coordination and collaboration, particularly with governments and health ministries throughout Africa. Public health education is also urgently needed in countries outside of Africa in order to ensure that risk is properly understood and public concerns do not escalate unnecessarily. To prevent future outbreaks, coordinated, multiscale, early warning systems should be developed that make full use of these integrated assessments, partner with local communities in high-risk areas, and provide clearly defined response recommendations specific to the needs of each community. ...” Key Learning Points ·         Significant political, social, and environmental changes have occurred in West Africa, likely contributing to the emergence of the most deadly Ebola outbreak in history. ·         Similarity in outbreak characteristics (including R0, symptoms, incubation time, and serial time) between West Africa and previous Ebola outbreaks suggests that there has not been any significant change in the virus affecting transmissibility. ·         Information collection and communication remain a challenge in resource-poor settings and specific strategies and tools will need to be developed to allow rapid identification and response within the context and constraints identified in the local environment. ·         Integrated approaches involving both human and animal health [“One Health”] must be developed that engage the research, law enforcement, and policy environments within these local settings. Please read complete article: http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0003652 Note: Co-authors of this piece, Kathleen A. Alexander, DVM, PhD is listed on the One Health Initiative Supporters list http://www.onehealthinitiative.com/supporters.php and Viriginia M. Dato, MD, MPH is a member of the One Health Initiative team’s Honorary Advisory Board http://www.onehealthinitiative.com/advBoard.php.

Veterinary Practice News – June 10, 2015 Why The Human Side Lags Behind in One Health Veterinarians continue to lead real-world advances in the collaboration on human, animal and environmental well-being. “Pioneers of the One Health movement to blend human, veterinary and environmental health are gaining respect, epidemic by epidemic, but capturing the attention of the human health care establishment remains a challenge. “You have to take the long view,” acknowledged Laura H. Kahn, MD, MPH, of the One Health Initiative team. “It took people over a century to realize the significance of basic sanitation, and lots of countries don’t even have that.” ...” Please read complete article http://www.veterinarypracticenews.com/Why-The-Human-Side-Lags-Behind-in-One-Health/

Food Safety News ‘Surprising’ Discovery Made About Chronic Wasting Disease New study shows that prions can bind to plants By Cookson Beecher | June 1, 2015 “An infectious brain disease that has been killing deer, elk and moose both in the wild and on “captive farms” continues to stalk the land, expanding its domain to 23 states and two Canadian provinces since it was first identified in captive mule deer in a Colorado research facility in 1967. Known as chronic wasting disease, or CWD, it has baffled scientists for decades. Where did it come from, and why is it spreading across the landscape? What health risks might it pose to humans who eat parts of infected animals? And can cattle get it from infected deer, elk, and moose, thus introducing it into the human food chain? ...” Read more: http://www.foodsafetynews.com/2015/06/researchers-make-surprising-discovery-about-spread-of-chronic-wasting-disease/#.VW34IU1FAdU  

Infection Ecology & Epidemiology (EEE) – The One Health Journal (Sweden) The case for a ‘one health’ approach to combating vector-borne diseases Bonto Faburay, DVM, PhD, Research Assistant Professor* Print this article Indexing metadata How to cite item Email this article (Login required) Email the author (Login required) Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA Citation: Infection Ecology and Epidemiology 2015, 5: 28132 - http://dx.doi.org/10.3402/iee.v5.28132 “Vector-borne diseases (VBDs) account for 17% of the estimated global burden of all infectious diseases, and transmission has become increasingly ubiquitous with the largest risk zones in Africa, Asia, and the Americas. As a major cause of morbidity and mortality in humans and livestock in pastoral and mixed farming communities in developing countries, VBDs reinforce the vicious cycle of poverty by limiting productivity and the ability to produce food or earn income to purchase food or medical services. Due to the influence of human activity on disease incidence and the direct and indirect impact on human health and livelihoods, VBDs are highly suited to ‘one health’ concept for combating infectious diseases. Increased human mobility, population growth, trade, and climate change constitute major risk factors for geographic expansion to new areas. ...” Please read complete article: http://www.infectionecologyandepidemiology.net/index.php/iee/article/view/28132 Note: Dr. Faburay is listed in the One Health Initiative Supporters page http://www.onehealthinitiative.com/supporters.php.  

Duke Kunshan University   Postdoctoral One Health Research Fellow Occupational Summary: This is a 2-year One Health research fellowship for a professional who will work 12 months a year  in the Global Health Research Center at DKU.  The incumbent is expected to engage in high quality, One Health-oriented research in the complex area of emerging infectious diseases in China and other low and middle income countries.  The incumbent will work as a DKU faculty member under the supervision of Professor Gray from DGHI/DKU and collaborate with other One Health research teams in the Duke-DKU international research network. The postdoctoral trainee holder is expected to demonstrate his/her progress by designing collaborative One Health research projects in partnership with international collaborators, through submitting research grants for funding, and by publishing research in international journals. The incumbent is also expected to be involved in DKU’s global health educational and training programs through occasional lectures, student supervision, etc.  Job Description https://dku.edu.cn/en/postdoctoral-one-health-research-fellow   Note:  Dr. Greg Gray is a member of the One Health Initiative team’s Honorary Advisory Board http://www.onehealthinitiative.com/advBoard.php.

A previously published/posted (2010) Important One Health Introductory Article Pertinent to this day... ILAR J (2010) 51 (3): 193-198. doi: 10.1093/ilar.51.3.193 This article appears in: One Health: The Intersection of Humans, Animals, and the Environment Introduction: One Health Perspective “The One Health concept is a worldwide strategy—a paradigm shift—for expanding interdisciplinary collaborations and communications in all aspects of health care for humans and animals. The synergism achieved will advance health care for the 21st century and beyond by accelerating biomedical research discoveries, enhancing public health efficacy, expeditiously expanding the scientific knowledge base, and improving medical education and clinical care. When properly implemented, it will help protect and save untold millions of lives in present and future generations. “One Health” promotes the integration of human, animal, and environmental health through communication and collaboration among physicians, osteopaths, veterinarians, wildlife professionals, environmental and public health experts, dentists, nurses, biomedical engineers, physicists, biochemists, plant pathologists, and others. ...” Read Article in Full : http://ilarjournal.oxfordjournals.org/content/51/3/193.full.pdf+html

U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases (NIAID) http://www.niaid.nih.gov  Ebola Vaccine Trial Opens in Liberia – February 2, 2015 Study Led by Liberia-NIH Partnership Will Test Two Experimental Vaccines  http://www.niaid.nih.gov/news/newsreleases/2015/Pages/PREVAIL.aspx

Excellent One Health Program Practiced at University of Pennsylvania’s College of Veterinary Medicine (“Penn Vet”) – USA Philadelphia, PA  The Future of Veterinary Medicine “At Penn Vet, we are driven from the perspective of One Health: humans, the environment, animals, living together harmoniously. Uniquely trained in comparative biology, veterinarians are the only members of the clinical profession – including human medical professionals – who see many different species, and understand medicine fundamentally such that all species benefit. Veterinarians approach medicine with a global perspective, supporting public health and making a huge impact on peoples well-being. To learn more about how Penn Vet supports One Health, visit www.vet.upenn.edu Click on: http://www.vet.upenn.edu/about/what-we-do/future-of-veterinary-medicine and see One Health video

  “ONE HEALTH”, a significant international public health/comparative medicine paradigm shift!  Why? How?   FINAL WVA/WMA Conference agenda per Dr. Zeev Noga May 13, 2015 http://www.onehealthinitiative.com/publications/FINALPROGRAM.pdf

United Kingdom Infectious Disease Surveillance and Monitoring System for Animal and Human Health: Summary of notable incidents of public health significance December 2014 to March 2015

Call for Nominations/Applications for Student Representatives on One Health Commission (OHC) Board of Directors (USA) Time Line: Applications Due to OHC- May 20, 2015 Student online survey / voting: May 21-June 3 Board Selection process: June 4-July 20 Students first Board Meeting: August 20 Also, please see One Health Commission Newsletter http://www.onehealthinitiative.com/publications/OHCNewsletterVol24-16-15Spring2015Final.pdf   Provided by:  Cheryl Stroud, DVM, PhD  Executive Director, One Health Commission  www.onehealthcommission.org/  cstroud@onehealthcommission.org  Adjunct Assistant Professor, Dept Clinical Sciences, NC State CVM  224-622-1839  Connect, Create, Educate for One Health

Reminder: 3rd GRF One Health Summit 2015 Fostering interdisciplinary collaboration for global public and animal health October 4-7, 2015 Davos, Switzerland http://onehealth.grforum.org/   Endorsed by One Health Initiative team and others—see: http://onehealth.grforum.org/partnership/endorsing-partners/ (scroll down) http://onehealth.grforum.org/about/scientific-and-technical-advisory-group/

An important biomedical research project... an ideal One Health project Open Access – PLOS bIOLOGY Unsolved Mysteries discuss a topic of biological importance that is poorly understood and in need of research attention. * E-mail: kaeber@uw.edu Affiliation: Department of Pathology, University of Washington, Seattle, Washington, United States of America ⨯ Why Is Aging Conserved and What Can We Do about It? http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002131  Jason N. Pitt, PhD, Matt Kaeberlein, PhD   Published: April 29, 2015 DOI: 10.1371/journal.pbio.1002131 Pitt JN, Kaeberlein M (2015) Why Is Aging Conserved and What Can We Do about It? PLoS Biol 13(4): e1002131. doi:10.1371/journal.pbio.1002131         Abstract “The field of aging research has progressed rapidly over the past few decades. Genetic modulators of aging rate that are conserved over a broad evolutionary distance have now been identified. Several physiological and environmental interventions have also been shown to influence the rate of aging in organisms ranging from yeast to mammals. Here we briefly review these conserved pathways and interventions and highlight some key unsolved challenges that remain. Although the molecular mechanisms by which these modifiers of aging act are only partially understood, interventions to slow aging are nearing clinical application, and it is likely that we will begin to reap the benefits of aging research prior to solving all of the mysteries that the biology of aging has to offer.” Drs. Pitt http://kaeberleinlab.org/people/jason-pitt and Kaeberlein http://www.pathology.washington.edu/faculty/kaeberlein are affiliated with the Department of Pathology, University of Washington, Seattle, WA (USA).  

Historic milestone physician/veterinarian global One Health conference: World Veterinary Association/World Medical Association   May 21– 22, 2015 Madrid, Spain Final program agenda http://www.wma.net/en/50events/20otherevents/80onehealth/ONE-HEALTH-2015---Final-Program.pdf  

One Health challenges explored in working paper series What drives differing responses to zoonotic diseases and is then used to justify different interventions and responses to disease is explored in a new working paper series from the Dynamic Drivers of Disease in Africa Consortium (www.driversofdisease.org). The series includes papers exploring the challenges to implementing One Health approaches to disease. All seven working papers in the series can be accessed from the STEPS Centre website (http://steps-centre.org/publication/dddac-pol-econ-wp-series/). Provided to One Health Initiative website April 14, 2015 by: Naomi Marks Project Communications Manager Dynamic Drivers of Disease in Africa Consortium | Twitter @DDDAC_org Social, Economic and Environmental Drivers of Zoonoses in Tanzania (SEEDZ) | Twitter @SEEDZ_TZ  ESRC STEPS Centre, Institute of Development Studies Tel: +44 (0) 1273 915606

Regional Workshop on MERS-CoV and ‘One Health’ Doha, Qatar 27–29 April 2015: Marriott Hotel  See Agenda Attachment and  http://www.onehealthinitiative.com/publications/ConceptNote_MERSWorkshop-Doha-final.pdf