One Health Publications

U.S. Centers for Disease Control and Prevention – Emerging Infectious Diseases Journal Volume 19, Number 12—December 2013 Historic Prevalence and Distribution of Avian Influenza Virus A(H7N9) among Wild Birds Sarah H. Olson, Martin Gilbert, Ming Chu Cheng, Jonna A.K. Mazet, and Damien O. Joly   Abstract We examined 48 published studies for which sample sizes could be ascertained to determine the historic prevalence of influenza A(H7N9) virus in wild bird populations and reviewed GenBank data to further establish its distribution. Low prevalence (0.0093%) in Asia suggests > 30,000 samples would be required to detect the H7N9 subtype in wild birds.     http://wwwnc.cdc.gov/eid/article/19/12/13-0649_article.htm

United States Department of Health and Human Services   One Health   http://www.globalhealth.gov/global-programs-and-initiatives/one-health/

Dirofilariosis in the Americas: a more virulent Dirofilaria immitis? Dantas-Torres F, Otranto D Abstract “Dirofilarioses are widespread diseases caused by filarioid nematodes (superfamily Filarioidea) of the genus Dirofilaria, which are transmitted by a plethora of mosquito species. The principal agent of canine dirofilariosis in the Americas is Dirofilaria immitis, which may also occasionally infest humans, resulting in pulmonary nodules that may be confounded with malignant lung tumours. Because human cases of dirofilariosis by D. immitis are relatively frequent in the Americas and rare in Europe and other eastern countries, where Dirofilaria repens is the main causative agent, the existence of a more virulent strain of D. immitis in the Americas has been speculated. Recently, a case of human ocular infestation by Dirofilaria sp. was diagnosed in Pará State, northern Brazil, where canine heartworm dirofilariosis is endemic. The nematode was shown to be morphologically and phylogenetically related to D. immitis but it was genetically distinct from reference sequences, including those of D. immitis infesting dogs in the same geographical area. This finding raised questions regarding the aetiology of human dirofilariosis in the Americas, since information on the genetic makeup of filarioids infesting dogs and humans is meagre. Further studies would be needed to better characterize filarioids infesting dogs, wild animals, and humans in the Americas and to assess the existence of a more virulent D. immitis strain in this continent. Finally, the competence of different culicid species/strains from Europe and the Americas as vectors of Dirofilaria species should be investigated. Such studies would help us to understand possible variations in transmission patterns and even to predict possible scenarios that may emerge in the future, with the introduction of non-endemic Dirofilaria species/strains in free areas through importation of infested animals, vectors, or both.” Parasites & Vectors 2013, 6 :288 (2 October 2013) http://www.parasitesandvectors.com/content/6/1/288

Florida Department of Health   One Health Newsletter Summer Issue Published—October 7, 2013   See http://www.floridahealth.gov/diseases-and-conditions/diseases-from-animals/one-health-newsletter/index.html  (new link)     http://www.doh.state.fl.us/environment/medicine/One_Health/SpringOHNL2013.pdf Summer 2013-Volume 6 Issue 3 (PDF 1 MB)

Biomedical Technology, Epidemiology and Food Safety Global Network: Brno, Czech Republic A One Health Supporter   Please see http://centaur.vri.cz/   Provided by:   Professor Karel Hruska, MVDr. CSc. Biomedical Technology, Epidemiology and Food Safety Global Network centaur@vri.cz

Five new important research updates published by Dynamic Drivers of Disease in Africa Consortium…   Please see:  http://steps-centre.org/2012/blog/latest-publications/ SEPTEMBER 2013 – “The Drivers of Disease Consortium has published five research updates, one for each of its case study countries. Each update outlines the background to the case study disease being investigated, describes the key questions the research team is exploring, along with some of the knowns and unknowns, and gives a brief outline of the research methodologies being followed.” The updates are available for download in PDF format: Situation Analysis Research Update Ghana Situation Analysis Research Update Kenya Situation Analysis Research Update Sierra Leone Situation Analysis Research Update Zambia Situation Analysis Research Update Zimbabwe Provided by: Naomi Marks Communications Officer Dynamic Drivers of Disease in Africa Consortium STEPS Centre Twitter: @DDDAC_org Sign up to our newsletter Tel: +44 (0) 1273 915606

A potential large scale “One Health in Action” ... another dynamic case for implementing One Health!   Vaccines against diseases transmitted from animals to humans: A one health paradigm   Opinion by: Laura H. Kahn, MD, MPH, MPP, Bruce Kaplan, DVM, Thomas P. Monath, MD, Jack Woodall, PhD, and Lisa A. Conti, DVM, MPH   “...Principles of utilizing the One Health approach, i.e. multidisciplinary/interdisciplinary collaborations between animal health and human health industries and regulators can definitely help develop immunization products for such purposes.  A visionary landmark September 2013 article published online by the notable medical virologist and vaccinologist physician *Thomas P. Monath, MD http://www.sciencedirect.com/science/article/pii/S0264410X1301270X gives reasonable guidelines to make it happen sooner rather than later.  Examples of such vaccines are listed including West Nile, brucellosis, Escherichia coli, O157:H7, rabies, Rift Valley fever, Venezuelan equine encephalitis, Hendra virus, Mycobacterium bovis, and Lyme disease.  Indeed, another September 2013 publication was published that discussed the dramatic food safety potential for using a vaccine in cattle to protect against human foodborne illness caused by E. coli, O157 http://www.pnas.org/content/early/2013/09/10/1304978110.full.pdf+html.   In simple terms, the idea is to develop vaccines that protect domestic animals and wildlife thereby establishing effective barriers against human infections.  Developing animal vaccines are less expensive and are less strictly regulated than are those for humans.  Hopefully a common sense One Health approach can go forward. ...”   Please read complete NEWS item on PDF View.

A signature One Health Program... One Health Institute – University of California, Davis (USA) Working at the interface of animals, people, and the environment to solve complex problems impacting health and conservation. “The UC Davis One Health Institute is home to many Centers, programs, projects and initiatives within the School of Veterinary Medicine and beyond. Our Executive Director is Dr. Jonna A.K. Mazet, DVM, MVPM, PhD and our scientists and educators are working throughout the UC Davis Campus, the UC System, State and Federal Agencies, and all over the world to advance the health of animals, people and the environment. We are continually updating and enhancing this website; please check back for updates.  The One Health approach addresses complex health problems on a platform that recognizes that the health of domestic animals, wildlife, and people are inextricably linked with each other and the environment. ...” Please see: http://www.vetmed.ucdavis.edu/ohi/                        and                       One of their seven (7) major/important Centers:                     http://www.vetmed.ucdavis.edu/onehealth/index.cfm Calvin Schwabe Project EXPLORING THE INTERSECTION OF HUMAN, ANIMAL, AND ENVIRONMENTAL HEALTH Our Mission “To strengthen the UC Davis School of Veterinary Medicines commitment to the One Health movement by educating veterinarians of the future to integrate human, animal, and ecosystem protection into their professional lives. The Calvin Schwabe One Health Project fosters a diverse and sustainable planet, with the goal of encouraging a new generation of veterinary expertise in the integration of better health for humans, animals, and their environment. To that end, One Health expands career pathways for veterinary students in disciplines such as public practice, wildlife and ecosystem health, food safety, herd health, disaster preparedness, rural health, and zoonotic disease threats.”

One Health in Action...   DVM360 MAGAZINE - Sep 1, 2013 By: John Lofflin, Contributing Author How veterinary medicine can save the world, Part 1: Curing disease   “In the next few months, were taking a close look at how veterinary medicine benefits people, not just animals. In this first installment, we meet a translational (cross-species) researcher whos in the process of revolutionizing orthopedic medicine—for people and pets. ...”   Please see attached PDF with article about veterinarian Dr. James “Jimi” Cook, a One Health supporter/advocate and prominent member of the One Health Initiative Autonomous pro bono Honorary Advisory Board http://www.onehealthinitiative.com/advBoard.php. Dr. Cook has worked collaboratively for over 8 years with One Health physician Dr. Sonny Bal, also an important member of the OHI Hon. Advisory Board.   Also see DVM360 Magazine links: http://veterinarynews.dvm360.com/dvm/ArticleStandard/Article/detail/821109; http://images2.advanstar.com/PixelMags/dvm360/digitaledition/2013-09.html     Permission to post on One Health Initiative website granted by:   Kristi Reimer Channel Director, News Editor, dvm360 magazine, dvm360.com News Advanstar Veterinary 8033 Flint St. Lenexa, KS 66214 (913) 871-3821 (office) (913) 871-3808(fax) dvm360.com/news  

One Health in Action...a food safety paradigm shift for public health!   “...because the vaccine targets the major source of human risk [cattle], we predict a reduction in human cases of nearly 85%...”   Proceedings of the National Academy of Sciences of the United States of America - September 16, 2013, doi: 10.1073/pnas.1304978110  PNAS. Predicting the public health benefit of vaccinating cattle against Escherichia coli O157   http://www.pnas.org/content/early/2013/09/10/1304978110.abstract http://www.pnas.org/content/early/2013/09/10/1304978110.full.pdf+html     Abstract Identifying the major sources of risk in disease transmission is key to designing effective controls. However, understanding of transmission dynamics across species boundaries is typically poor, making the design and evaluation of controls particularly challenging for zoonotic pathogens. One such global pathogen is Escherichia coli O157, which causes a serious and sometimes fatal gastrointestinal illness. Cattle are the main reservoir for E. coli O157, and vaccines for cattle now exist. However, adoption of vaccines is being delayed by conflicting responsibilities of veterinary and public health agencies, economic drivers, and because clinical trials cannot easily test interventions across species boundaries, lack of information on the public health benefits. Here, we examine transmission risk across the cattle–human species boundary and show three key results. First, supershedding of the pathogen by cattle is associated with the genetic marker stx2. Second, by quantifying the link between shedding density in cattle and human risk, we show that only the relatively rare supershedding events contribute significantly to human risk. Third, we show that this finding has profound consequences for the public health benefits of the cattle vaccine. A naïve evaluation based on efficacy in cattle would suggest a 50% reduction in risk; however, because the vaccine targets the major source of human risk, we predict a reduction in human cases of nearly 85%. By accounting for nonlinearities in transmission across the human–animal interface, we show that adoption of these vaccines by the livestock industry could prevent substantial numbers of human E. coli O157 cases.

A signature One Health Program Promoting Global Health Security and Human/Animal clinical health (comparative medicine/surgery research)...   University of Missouri – Columbia, MO 65211 (USA)   “The University of Missouri offers unmatched opportunities for collaboration in animal and human health. MU is the state’s major public research university with the state’s only College of Veterinary Medicine; Colleges of Agriculture, Food and Natural Resources, Engineering and Human Environmental Sciences; Bond Life Sciences Center; Schools of Medicine, Nursing and Health Professions; and the most powerful university research reactor in the country. The initiative also connects with research and instruction in health care delivery, policy, business models, medical ethics and the culture of healthy living. ...” PLEASE SEE: http://mizzouadvantage.missouri.edu/medicine/ and http://libraryguides.missouri.edu/onehealth

A signature One Health program... One Border One Health   A California - Baha California Regional Network Mission / Misión One Border One Health is a binational multidisciplinary cooperative building more resilient and healthy border communities by identifying, responding, and creating sustainable solutions to health risks at the human-animal-environmental interface.   Una Frontera Una Salud es un esfuerzo de cooperación multidisciplinaria binacional para construir comunidades fronterizas saludables con la capacidad de identificar, responder, y crear soluciones sustentables para los riesgos de la salud en la interacción humano-animal-ambiental.   Read more: http://www.oneborderonehealth.com/

Halley Faust Comments Finding the right balance in contemporary issues One Health: the Balance between Animal and Human Health  August 21, 2013 – 1:31 pm Categories: Animal-Human Medicine, Prevention | Post a comment     Halley S. Faust, MD, MPH, MA President American College of Preventive Medicine 1260 Vallecita DriveSanta Fe, NM 87501 Voice: 505-501-8181 FREE hfaust@jeromecapital.com @onHealthPolicy Blog: www.halleycomments.com “Animals and humans interact in many more ways than we think about in domestic suburbia.  Sure, we know that animal farmers are constantly in contact with their produce, and we are happy to pet our domestic cats and dogs.  Sure we recognize that some wild animals get rabies or, here in the desert of New Mexico, occasionally someone comes down with plague because of flea bites from infected indigenous rodents (our first case of this year was just last week).  And we’ve all heard of bird flu. ...”   Please read more: http://halleyfaust.wordpress.com/ or see attachment.

A major public health issue...that requires implementation of One Health concept, i.e. a serious widespread collaborative, interdisciplinary approach!   U.S. Centers for Disease Control & Prevention   Antibiotic / Antimicrobial Resistance   Threat Report 2013 This report, Antibiotic resistance threats in the United States, 2013 gives a first-ever snapshot of the burden and threats posed by the antibiotic-resistant germs having the most impact on human health.  Each year in the United States, at least 2 million people become infected with bacteria that are resistant to antibiotics and at least 23,000 people die each year as a direct result of these infections. Many more people die from other conditions that were complicated by an antibiotic-resistant infection. Antibiotic-resistant infections can happen anywhere. Data show that most happen in the general community; however, most deaths related to antibiotic resistance happen in healthcare settings such as hospitals and nursing homes.   Please see: http://www.cdc.gov/drugresistance/threat-report-2013/

American Veterinary Medical Association (AVMA) Recognizes One Health Initiative Team and One Health Initiative website   Yesterday, September 11, 2013, in a letter (please see attached PDF of letter), the President of the American Veterinary Medical Association, Clark Fobian, DVM, notified the One Health Initiative Autonomous pro bono team about “... the AVMA’s public support and recognition for your efforts to promote public health via the One Health Initiative website, and elsewhere. ...”.  Dr. Fobian went on to say, “...We likewise look forward to achieving the comprehensive recognition and use of One Health as the necessary strategy to tackle complex challenges impacting the health of people, animals, and our environment.”   The One Health Initiative Autonomous pro bono Team includes two physicians, two veterinarians and a health research scientist PhD: Laura H. Kahn, MD, MPH, MPP http://www.onehealthinitiative.com/publications/LauraKahnBiographyJuly2013.pdf, Bruce Kaplan, DVM http://www.onehealthinitiative.com/publications/BruceKaplanBiographyJune2013.pdf, Thomas P. Monath, MD http://www.onehealthinitiative.com/publications/TomMonathBiographyJune2013.pdf, Jack Woodall, PhD http://www.onehealthinitiative.com/publications/JackWoodallBiographyJune2013.pdf, and Lisa A. Conti, DVM, MPH http://www.onehealthinitiative.com/publications/LisaContiBiographyJune2013.pdf.

      North American Veterinary Community’s *Clinicians Brief Journal (USA) Features One Health Initiative Capsules   September 2013 issue – Please see attached PDF    *Clinician’s Brief, the official Journal of the North American Veterinary Community (NAVC), adopted support and advocacy of the One Health concept in its October 2011 issue.     The NAVC http://www.navc.com/ conducts a prominent and outstanding yearly meeting in Orlando, Florida (USA).  It is one of the largest veterinary medical continuing education events in the world.  A focus is maintained “on a single goal—providing high quality, practical information to every member of the veterinary [medical] professional team.”    The One Health Initiative team believes Clinician’s Brief to be the only peer reviewed small animal medicine/surgery journal in the world to have adopted and implemented a significant identifiable One Health oriented section (One Health Initiative Capsules) in their monthly publication issues.   Provided exclusively to One Health Initiative website by:      Michelle N. Munkres, Editorial Director and Indu Mani, DVM, DSc, Editor    NAVC Clinician’s Brief     http://www.cliniciansbrief.com/     Educational Concepts, LLC     2021 S. Lewis Avenue #760    Tulsa, OK 74104     T: (918) 710-4610 begin_of_the_skype_highlighting  (918) 710-4610 FREE  end_of_the_skype_highlighting               F: (918) 749-1987    NOTE: Dr. Mani serves as a member of the One Health Initiative Autonomous pro bono team’s Hon. Advisory Board http://www.onehealthinitiative.com/advBoard.php.

University of Minnesota Center for Infectious Disease Research and Policy (CIDRAP)   Questions raised about MERS-CoV bat report  MERS-CoV Robert Roos | News Editor | CIDRAP News   Aug 30, 2013   “In the week and a half since scientists announced they had found a fragment of virus in a bat that seemed to match the Middle East respiratory syndrome coronavirus (MERS-CoV), many have raised questions about whether the fragment really was from the same virus that is striking people in Saudi Arabia and elsewhere in the Middle East. ...”   Please read entire article: http://www.cidrap.umn.edu/news-perspective/2013/08/questions-raised-about-mers-cov-bat-report

Submitted to One Health Initiative website August 14, 2013 and posted September 4, 2013.   One Health approaches can lead to better preparedness in prevention and control of Zoonoses   *Delia Grace, MVB, MSc, Cert Wel, PhD; Bernard Bett, BVM, MVEE, PhD; and Steve Kemp, BSc, PhD   “A group of research experts associated with the Dynamic Drivers of Disease in Africa Consortium have called for a system-based ‘One Health’ approach to help catalyze better preparedness and surveillance that are informed by cross-disciplinary approaches. ...”   *NOTE: Drs. Grace, Bett and Kemp are One Health Supporter/Advocates http://www.onehealthinitiative.com/supporters.php.   Please read full article on attached PDF.

Texas A & M (USA) ONE HEALTH Report – August 2013   “Howdy! The One Health program at TAMU is up and running! So many things have happened or are in the process of happening since our inaugural TAMU One Health Report. I believe you will find this report interesting and, as always, your comments and suggestions are welcome. ...”   Mike Chaddock, DVM, Assistant Dean for One Health and Strategic Initiatives College of Veterinary Medicine & Biomedical Sciences, Texas A&M University (USA)   Please read full Report on attached PDF   NOTE: Dr. Chaddock is a notable One Health Supporter/Advocate http://www.onehealthinitiative.com/supporters.php.

Letter to the Editor: Missouri Medicine - [Kahn, LH.  One Health = One Great Issue (Letter), Missouri Medicine 2013;110:292.]   This Letter to the Editor (see PDF link) was submitted and published in the July/August Missouri Medicine Journal issue in response to the outstanding One Health issue published in the May/June issue of Missouri Medicine.  This was posted on the One Health Initiative website’s Publications page http://www.onehealthinitiative.com/publications/OneMedicineBook.pdf  June 7, 2013