One Health Publications

A single dose investigational subunit vaccine for human use against Nipah virus and Hendra virus

February 9, 2021

Published: 08 February 2021

Abstract

Nipah and Hendra viruses are highly pathogenic bat-borne paramyxoviruses recently included in the WHO Blueprint priority diseases list. A fully registered horse anti-Hendra virus subunit vaccine has been in use in Australia since 2012. Based on the same immunogen, the Hendra virus attachment glycoprotein ectodomain, a subunit vaccine formulation for use in people is now in a Phase I clinical trial. We report that a single dose vaccination regimen of this human vaccine formulation protects against otherwise lethal challenges of either Hendra or Nipah virus in a nonhuman primate model. The protection against the Nipah Bangladesh strain begins as soon as 7 days post immunization with low dose of 0.1 mg protein subunit. Our data suggest this human vaccine could be utilized as efficient emergency vaccine to disrupt potential spreading of Nipah disease in an outbreak setting.

 

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Genomic epidemiology identifies emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States

February 9, 2021

Genetic epidemiology is a relatively new medical discipline that seeks to understand how genetic factors interact with the environment in the context of disease in populations. Areas of study include the causes of inherited disease and its distribution and control.

 

 

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How we can stop animals making us sick

February 8, 2021

Macquarie University/The Lighthouse

“The best way to prevent outbreaks of disease passed from animals to humans lies in the One Health approach, says Macquarie University philosopher Dr Jane Johnson. 

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Five Steps To Prevent The Next Pandemic

February 5, 2021

With 2 million dead worldwide and a year’s worth of economic devastation, it should be harder to look the other way now.

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COVID-19 Vaccine Update by Carrie La Jeunesse, DVM, CT, CFE

February 5, 2021

In this informational session, Dr. Carrie La Jeunesse will provide a synopsis of current information on the two mRNA COVID-19 vaccines currently being deployed under the Emergency Use Authorization in the United States.

Basic vaccine information
Emergency use authorization vs. full licensing
Susceptibility of different populations
Tiered vaccine administration roll-out
Side effects and precautions
Vaccine resistance, at risk-populations, and health communications
What COVID-19 vaccines might mean for/in the workplace.

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The Sleeping Giants of Vaccine Production Awaken

February 4, 2021

Stirred to action by the COVID-19 pandemic, vaccine stalwarts mobilize new formats, accelerate development, and scale up manufacturing

 

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Pharmaceutical giants not ready for next pandemic, report warns

January 26, 2021

Ten of the world’s most infectious diseases identified by the WHO not being catered for by drug firms

 

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To Prevent Pandemics and Protect Biodiversity, Combat Wildlife Crime

January 26, 2021

… it threatens global public health and the extinction of endangered species. … animal and human health, and the need for a “One Health” approach, …

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Wildlife Trade, Pandemics and the Law: Fighting This Year’s Virus with Last Year’s Law

January 24, 2021

Wingard, J., S. Belajcic, M. Samal, K. Rock, M. L. Custodio, M. Heise, S. Fiennes, C. Machalaba, A.A. Aguirre. (2020). Wildlife Trade, Pandemics and the Law: Fighting This Year’s Virus with Last Year’s Law. Legal Atlas, LLC. January 2021.

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