One Health Publications

“… Through the LGHS project, USAID provides local partners in Zambia with grants and technical assistance (TA) in prioritized technical areas. In fiscal year 2024–2025, LGHS will award three to four grants to local organizations to address zoonotic disease through risk communication and community engagement, community-based surveillance, and One Health workforce development. One Health recognizes that the health of people, animals, and the environment are interconnected.”

ANTICIPATED RESULTS FOR 2024

• Award three to four grants to local organizations to address zoonotic disease through risk communication and community engagement, community-based surveillance, and One Health workforce development.
• Each grantee will integrate up-to-date best practices in their programming to sustainably continue global health security work.

Abstract

The One Health approach, which emphasizes the interconnection between human, animal, plant, and environmental health, has gained significant attention as a framework for addressing global health challenges. This study presents a thorough bibliometric analysis of One Health research, utilizing the Web of Science Core Collection database, covering the period from 1989 to 2024. The analysis uncovers a substantial increase in scientific output over the years, reflecting the growing importance of this interdisciplinary field. The research reveals a notable shift in focus from traditional areas such as microbiology and infectious diseases to broader public health issues, including healthcare management, policy development, and food security, with particular attention to plant health, crop production, and the use of pesticides. Through advanced tools like Biblioshiny and VOSviewer, this study identifies prolific authors, leading journals, and emerging research themes shaping the One Health domain. The findings highlight the critical role of international collaboration in advancing this field and underscore the need for interdisciplinary approaches in both established and emerging research areas. By offering a comprehensive overview of the current landscape, this bibliometric evaluation serves as a valuable guide for researchers, policymakers, and stakeholders, emphasizing the essential role of One Health in developing strategies to combat complex health issues on a global scale.

One Health is an integrated, unifying approach that aims to sustainably balance and optimize the health of people, animals and ecosystems. It …

“… Released in conjunction with the 8th World One Health Congress (WOHC) in Cape Town, South Africa, this report complements TRAFFIC’s ‘From Bush to Butchery‘ findings in Tanzania, which will be presented at the WOHC. The WOHC brings together global experts—including researchers, policymakers, and representatives from international institutions—to discuss One Health solutions for wildlife management, trade, and the health risks associated with consuming wild meat.

Porcupines were the top-traded species at markets  –  Over 50% of interviewees in this study do not believe bushmeat transmits zoonotic diseases 75% of bushmeat carcasses were transported by motorbike  – Over 50% of traded taxa were porcupines, antelopes, hares, monkeys, and red river hogs

Notes:

About the One Health Approach

One Health is an integrated, unifying approach that aims to sustainably balance and optimise the health of people, animals, and ecosystems. Find out more here.  …”

Abstract

Acid-suppressant drugs (ASDs) have revolutionized the treatment of acid-related disorders such as gastroesophageal reflux and gastrointestinal ulceration in both human and veterinary species. However, continued advancement in this field is dependent on a shared understanding of both human and veterinary research as well as an appreciation for species similarities and differences. In this Currents in One Health article, we will compare the efficacy of and indications for ASDs in humans and small animals, noting species differences and knowledge gaps when applicable. We will also highlight areas where further research is needed, specifically emphasizing the need for more feline research and a better understanding of which diseases may benefit from gastroprotection. Finally, given the rising overuse of ASDs in both human and veterinary medicine, we will explore the known adverse effects of these drugs in dogs and cats. This article is focused on our current understanding of these drugs in veterinary medicine and their clinical implications. The companion Currents in One Health article by Gould et al, AJVR, October 2024, will explore the future of ASD research and use by evaluating these drugs’ pH-independent effects in humans and rodent models.

“Described below is an effort to give public visibility to what has tended to be an underpublicized aspect of the One Health concept, i.e., the linkages between human, animal, plant, and ecosystem well-being. Much recent global attention and resources have rightly been applied to preserve biodiversity affected by climate change, industrialization, and urbanization, each of which has, in some instances, decimated scarce species.  …”

Science

Understanding immune response in animals pivotal to developing breeding techniques and more to prevent disease before animals sicken

Conclusion

One of the central goals in research within the One Health theme is to understand the complexity of direct and/or indirect factors that drive the dynamics of pathogens in ecosystems and facilitate spillovers between species^37,38,39. Although there are multiple connections between cancerous pathologies, infections and pathogen transmission⁹, to our knowledge, no study has attempted to link the two within a One Health perspective. Such concerns are nevertheless important because several human activities influence the prevalence of cancers in nature^11,12,14. In this work, we explored a key prediction proposed by Dujon et al.¹⁰—namely, that tumoral individuals within communities could play the role of symbiont amplifiers, increasing the likelihood of spillover to other species.

Our study provides the first preliminary evidence that tumoral individuals, at least in Hydra, could act as a super spreader of symbionts within and between species. Our findings confirm that tumoral hydras exhibit higher ciliate loads and demonstrate that they have a more pronounced spillover effect compared to healthy ones, although with different consequences according to the species introduced. While the reasons for the higher ciliate colonization of tumoral hydras remain unclear (see also²⁵), these results represent a first step towards full proof of concept, assessing the potential implications of tumor-induced vulnerability to infections for ecosystem functioning⁸. Further research using more complex experimental approaches is needed to understand the proximate mechanisms underlying the spillover effect of tumoral individuals and to generalize the results obtained to other models, thus exploring their ecological realism. By improving our understanding of these processes through the One Health approach, we can enhance strategies for managing disease transmission and preserving ecosystem stability in natural populations.

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Editor’s note:  See  Cancer – One Health Initiative (https://onehealthinitiative.com/?s=cancer)

“… Clearly, addressing multi-host, zoonotic-origin outbreaks requires a cross-sectoral approach addressing human, animal, and ecosystem health. Such a “One Health” approach remains weak in the Proposal for the WHO Pandemic Agreement—with numerous caveats and few concrete mechanisms to prevent future zoonotic diseases from spilling over between wildlife, humans, and livestock. This is disappointing to say the least. …”