One Health Publications

Medical research British vet[erinarian] wins top research award for breakthrough anaesthetic [propofol] https://www.theguardian.com/science/2018/sep/11/john-glen-wins-lasker-award-anaesthetic-propofol http://www.laskerfoundation.org/media/filer_public/6f/c5/6fc57545-da5e-4fa7-a710-9a809932cb56/2018_awards_press_release.pdf Note: Propofol is a short-acting medication that results in a decreased level of consciousness and lack of memory for events. It is marketed as Diprivan among others and is one of the most widely used anaesthetics in the world. Its uses include the starting and maintenance of general anesthesia, sedation for mechanically ventilated adults, and various procedural sedations.

Goddard Forums inaugural Pa. One Health Symposium focuses on zoonotic diseases September 7, 2018 UNIVERSITY PARK, Pa. — A unique gathering of physicians, veterinarians, ecologists and conservationists took place in Hershey recently with the goal of improving human, animal, plant and ecosystem health in Pennsylvania. The inaugural Pennsylvania One Health Symposium, which focused on zoonotic diseases — infectious diseases that are caused by viruses, bacteria, parasites and fungi spread between animals and people — was sponsored by the Maurice K. Goddard Chair in Forestry and Environmental Resource Conservation in Penn States College of Agricultural Sciences. Lead speakers at the symposium were Dr. Laura Kahn, Woodrow Wilson School of Public and International Affairs, Princeton University; Jack Shere, chief veterinary officer, U.S. Department of Agriculture, Animal and Plant Health Inspection Service; Peter Hudson, Verne M. Willaman  Professor of Biology and director of the Huck Institutes of the Life Sciences at Penn State; and James Holt, Pennsylvania Animal Health and Diagnostic Commission member. ...  Read complete at https://news.psu.edu/story/535220/2018/09/07/impact/goddard-forums-inaugural-pa-one-health-symposium-focuses-zoonotic

Journal of Animal Genetics, Transgenesis and Zoonoses (JAGTZ) http://www.lidsen.com/journals/jagtz is an international peer-reviewed Open Access journal that publishes novel studies, opinions and reviews to advance the science of animal genetics, transgenesis, zoonoses and aquaculture, using a multidisciplinary approach and methods involving genetics, genomics, microbiology, virology, bacteriology, parasitology, immunology, epidemiology, transgenic and genome edited animals, etc. Research and discussions that promote the One Health concept are greatly welcome. JAGTZ covers studies on all species including domestic animals, wildlife and aquatic animals.  Topics include but are not limited to: Animal Genetics: molecular genetics; immunogenetics; molecular biology; functional genomics; mapping of genes, traits and QTLs; genetic diversity of economically important and/or domesticated animals.  Transgenesis: transgenic and genome editing of economically important and domesticated animals; cloning; breeding of domestic and aquatic animals; physiology, biochemistry, development genomics, genetics behavior, and exploitation of transgenic animals. Zoonoses: pathogenesis, etiology, diagnosis, immunology, epidemiology and control of bacterial, viral, parasitic, mycotic diseases; veterinary and public health; comparative medicine; modeling; monitor and regulatory systems and policies; One Health.  JAGTZ will provide a valuable forum for cross-fertilization of ideas and techniques in the areas of animal genetics, transgenic technology and zoonotic diseases. JAGTZ publishes research articles, reviews, communications, case reports, opinion articles, comments, short notes, book reviews, etc. Authors should present their results as outlined in the section Instructions for Authors. Manuscripts should advance the scientific knowledge and be authored by scientists with expertise in the areas described above.

Establishing research priorities to improve the one Health efficacy of Australian general practitioners and veterinarians with regard to zoonoses: A modified Delphi survey Steele, SG, Booy, R & Mor, SM (2018) Establishing research priorities to improve the one Health efficacy of Australian general practitioners and veterinarians with regard to zoonoses: A modified Delphi survey, One Health https://doi.org/10.1016/j.onehlt.2018.08.001 https://www.sciencedirect.com/science/article/pii/S2352771418300235?viaihub Abstract While general medical practitioners (GPs) and veterinarians are often the first line responders in the face of a disease outbreak, pathways to improving the One Health efficacy of these clinicians remain unclear. A two-phase modified Delphi survey of professionals with known expertise in One Health (‘expert panel’) was used to 1) identify key knowledge, attitudes and practices (KAPs) of GPs and veterinarians that would be consistent with a One Health approach to zoonoses; and 2) determine priorities for future surveys with Australian GPs and veterinarians to identify important gaps that impede effective diagnosis and management of zoonoses. A list of 13 topics/sub-topics, as well as a list of 25 specific zoonotic diseases/agents emerged from the first phase of the survey. In the second phase the expert panel identified general knowledge of the clinical aspects and epidemiological aspects of zoonoses, as well as risk management practices, as the most important KAPs and research priorities for both GPs and veterinarians. In terms of diseases, the expert panel regarded knowledge of Hendra virus, Q fever, Australian bat lyssavirus (ABLV), anthrax and Brucella suis most important for veterinarians, whilst for GPs, Q fever, gastrointestinal/foodborne diseases, influenza, ABLV and local vector-borne diseases were found to be most important by the expert panel. Some differences were noted in terms of prioritization of topics/sub-topics and diseases/agents according to expert background (veterinary and non-veterinary). The Delphi survey technique enabled efficient collection of data from a diverse range of One Health ‘experts’/specialists and provided clear priorities for proposed future research, and potentially for educational interventions to improve One Health efficacy of clinicians.

Nobel Laureate Addresses One Health at 5th International One Health Congress Meeting in Saskatoon, Canada https://mailchi.mp/onehealthplatform/world-one-health-congress-free-lecture-202629?e=49188b2102  

 http://sites.globalhealth.duke.edu/dukeonehealth/    ISSUE 6 September 2018     Recent Publications   Duke Student Research Project Documents Human Exposure to Swine Viruses In the summer of 2017, a team of Duke students conducted research with Malaysian collaborators in demonstrating the presence of a number of pig viruses in pigs, pig environments, and pig workers noses. The research is remarkable in showing a possible route for novel pig viruses to infect men.   Read more       Duke Graduate Student Finds High Prevalence of Respiratory Syncytial Virus Among Patients in Sarawak, Malaysia Through an eight-week, cross-sectional pilot study, Duke Global Health MSc student, Jane Fieldhouse, in collaboration with a number of US and Malaysian collaborator, sought to estimate the prevalence of and to identify risk factors for respiratory syncytial virus (RSV) and parainfluenza virus (PIV) among patients with pneumonia at Sibu and Kapit Hospital in Sarawak, Malaysia. Read more       U.S. Scholars Collaborate with Georgian Scientists in Studying Causes of Pneumonia Scholars from the University of Michigan, Duke University, and the Republic of Georgia teamed up to study causes of pneumonia among patients in and around Tbilisi, Georgia.   Read more     Duke One Health Activities   Shandong University Announces China’s First Ecohealth/One Health Institute On August 2nd, Shandong University approved a proposal to create an Ecohealth/One Health Institute which is likely the first ever such institute in China. This new Institute will be comprised of Chinese and international professionals working across their disciplines of human health, veterinary health, and environmental health in tackling some of China’s most complex health problems.    Read more       US and Mongolian Scholars Conduct One Health Research in Mosquito-Borne Viruses A team of three fellows, including one US and two Mongolian scientists, are working with Mongolian program advisors at the Institute of Veterinary Medicine in Ulaanbaatar, Mongolia, to detect viruses which may be causing disease in humans and animals. Through this NIH-funded program, Natalie Wickencamp (USA),Saranzaya Enebish (Mongolia), and Batnasan Yondondorj (Mongolia) are collecting and studying specimens collected from humans, domestic animals, wildlife, and mosquitoes. Using molecular detection methods, they are detecting arboviruses which may be circulating in Mongolia. Natalie (middle) writes:   “Our team is currently conducting fieldwork while the weather is still warm enough to permit specimen collection. We have selected five different field sites across Mongolia based on their potential for a large mosquito habitat and/or for their close proximity to the Inner Mongolia Autonomous Region in China, where there have been recent reports of a large variety of arthropod-borne viruses. Once we conclude the fieldwork portion of our study, we will analyze the specimens that we collect for West Nile virus, Japanese encephalitis virus, Getah virus and Batai virus using real-time PCR molecular assays. Our 20-month pilot study will help identify emerging infectious diseases affecting nomadic herders and inform policymakers on current public health needs.”       Upcoming Event   <tr style=

The One Health Platform organizes its One Health congresses on a biennial basis. These meetings are the world’s premier conferences for the global One Health community as they bring together One Health advocates for four days of inspiring lectures, debates, workshops and symposia.  In evidence of the ground-breaking and captivating nature of our congresses, we have assembled a selection of lectures on different One Health topics for you. These contributions have been video-recorded during the recent 5th International One Health Congress in Saskatoon. We are pleased to share these free lectures with you in a weekly newsletter. 18 single episodes in 2018. https://mailchi.mp/onehealthplatform/world-one-health-congress-free-lecture?e=49188b2102

Global Health Center One Health Approach REGISTER!  We are delighted to invite you to attend our upcoming conference Application of the One Health Approach to Global Health Centers.  This conference, the fifth in our biennial series, will be held on December 3rd and the morning of the 4th at Einstein and is being organized by the Einstein Global Health Center in collaboration with EcoHealth Alliance and the Future Earth oneHEALTH global research project.  This conference builds on strong high-level support for One Health and Planetary Health, recognizing that implementation of inter-disciplinary approaches on the ground remains limited due to a wide range of competing priorities and a lack of awareness and involvement of certain communities.  While the veterinary medical community, and increasingly the public health community, have led One Health efforts to date, the human medical community has had limited engagement in One Health efforts, with few avenues articulated in terms of practical implications, opportunities, and benefits for involvement.  The relevance of interdisciplinary approaches is increasingly recognized as we face significant health consequences associated with rapid and widespread environmental and anthropogenic change. The pursuit of human, veterinary, and environmental health separately leads to an incomplete understanding of disease risks, resulting in missed opportunities for mitigating and adapting to threats and impacts. Studies of physicians reveal limited awareness of the environmental health aspects of medical problems in the patient care setting, as well as low levels of awareness about prevention or treatment of zoonotic diseases, which may hinder timely diagnosis and epidemiological investigation. While there have been calls for training health professionals in systems thinking to better prepare them to face these issues, at present One Health education efforts in medical schools are in their infancy, lagging behind veterinary schools which have made One Health a central part of their curricula. Wider adoption of One Health approaches in clinical care will require educating and training health care providers in certain novel competencies. We seek to bring representatives from the different areas of practice, often siloed, to discuss critical issues that are faced in order to focus more attention on the One Health approach and its application to both medical school curriculum and clinical practice. We believe this approach can be highly beneficial for the medical and global health communities in addressing infectious and non-infectious disease challenges, particularly as countries seek to operationalize One Health and other interdisciplinary approaches.  Our speakers represent such organizations as EcoHealth Alliance, NYC DOMH, CDC, World Bank, WHO, the Center for Disease Dynamics, NIAID Office of Biodefense Translational Resources, UC Davis One Health Institute, and Duke University, among others. Registration link:  www.eeds.com/live/418145  Tentative agenda  See: http://www.einstein.yu.edu/centers/global-health/events/one-health-approach.aspx Provided by: Jill Raufman, MS, MPH Director, Medical Student Global Health Programs Associate Director, Global Health Center Principal Associate, Department of Pathology Albert Einstein College of Medicine 1300 Morris Park Avenue/Block 505/Bronx NY 10461 Phone: (718) 430-3518    Fax: (718) 430-2521 Email: jill.raufman@einstein.yu.edu    Web: http://www.einstein.yu.edu/globalhealth

NEWS RELEASE Media Contact: Elizabeth.Story@adtalem.com 1-815-545-4242 “One Health Research Foundation Announces Inaugural Board of Directors Organization promotes research and training with emphasis on Caribbean MIRAMAR, Florida – August 29, 2018 The One Health Research Foundation (OHRF) announces its formation as a 501(c)(3) non-profit public charity, its inaugural Board of Trustees along with its mission to “improve human, animal and environmental health in the Caribbean and other tropical areas of the world through support of integrative, multidisciplinary research and innovation.” ... Please read complete News Release on attached PDF Provided by: A. Lee Willingham BSc, DVM, PhD Associate Dean for Research and Postgraduate Studies Professor of One Health Institutional Official Presidente/President ACACPMT  2017-2019   www.rossu.edu/veterinary-school *Note: Dr. Willingham is a longstanding recognized One Health leader.

Ebola Species Found in Bats Ahead of Any Potential Outbreak UC Davis The discovery was made by scientists at the University of California, Davis, One Health Institute and Columbia Universitys Center for Infection and ... Scientists Discover a Sixth Species of Ebola Virus — in Bats - Live Science Full Coverage

“How can a One Health approach mitigate the most prevalent health risks today?” See: https://www.scitecheuropa.eu/one-health-approach/88605/

AlignCare’s “one health” model [‘Humanitarian deed by One Health activists’]  See https://news.utk.edu/2018/07/30/ut-awarded-2-8m-grant-to-develop-system-to-aid-access-to-veterinary-care/

Saving Lives By Taking A One Health Approach https://www.cdc.gov/onehealth/multimedia/factsheet.html

One Health Education Submitted to the One Health Initiative website August 20, 2018 by: *Mike Chaddock, DVM, EML, Associate Dean for Administration, College of Veterinary Medicine, Michigan State University, 784 Wilson Road, Room G100, East Lansing, MI 48824; Office: 517-884-7438; Cell: 703-819-1343; www.cvm.msu.edu; http://www.onehealthinitiative.com/publications/Dr.MikeChaddockBIOGRAPHYAugust2018.pdf    There is compelling evidence that our planet is in peril. Human, wildlife and domesticated animal populations face growing health risks from such things as climate change, population growth, zoonotic pandemics and increased urbanization. These health risks are impacted by local and global environmental factors. One Health is a collaborative effort of multiple disciplines working locally, nationally, and globally to attain sustainable optimal health and well-being for humans and animals. It is the intersection and inextricable link between human health and animal health, and the connections between health and natural and man-made environments.  For many individuals, implementing One Health concepts and their related socioeconomic impacts is a cultural, behavioral and paradigm shift.   Many One Health concepts are driven by socioeconomic issues which include, but are not limited to:  population growth; nutritional, agricultural, and trade practices; globalization; shift in land use; accelerated urbanization; deforestation; encroachment on wildlife; and climate change. Now is the time for academic institutions to step forward in leading new One Health initiatives to create impactful, relevant research-driven solutions and train the next generation of innovative leaders. One Health concepts are ideally suited to provide robust, system-wide health-related solutions that the global society will need and expect. ... PLEASE READ COMPLETE ARTICLE ON ATTACHED PDF 

https://www.medicalbag.com/medicine/mammalian-divide-medical-students/article/789286/   Bridging the Mammalian Divide, One Medical Student at a Time Medical Bag The elective is part of the One Health Initiative, which promotes collaboration between veterinarians and physicians. Harvards elective is still new, but ... “...The elective is part of the One Health Initiative, which promotes collaboration between veterinarians and physicians. Harvards elective is still new, but the trend doesnt show signs of stopping. ...”    

The Junior Disease Detectives: Operation Outbreak Graphic Novel https://www.cdc.gov/flu/resource-center/freeresources/graphic-novel/index.html?CDC_AA_refVal=httpswww.cdc.govflugraphicnovelindex.html

Survival: One Health, One Planet, One Future  Watch for: One Health Book:  https://www.crcpress.com/Survival-One-Health-One-Planet-One-Future/Lueddeke/p/book/9781138334953.  Expected release date is now 25 SEPTEMBER.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900445/ Front Public Health. 2018; 6: 104. Published online 2018 Apr 9. doi:  10.3389/fpubh.2018.00104 PMCID: PMC5900445 PMID: 29686984 A Mini Review of the Zoonotic Threat Potential of Influenza Viruses, Coronaviruses, Adenoviruses, and Enteroviruses Emily S. Bailey,1,2,* Jane K. Fieldhouse,1,2 Jessica Y. Choi,1,2 and Gregory C. Gray1,2,3,4 Abstract During the last two decades, scientists have grown increasingly aware that viruses are emerging from the human–animal interface. In particular, respiratory infections are problematic; in early 2003, World Health Organization issued a worldwide alert for a previously unrecognized illness that was subsequently found to be caused by a novel coronavirus [severe acute respiratory syndrome (SARS) virus]. In addition to SARS, other respiratory pathogens have also emerged recently, contributing to the high burden of respiratory tract infection-related morbidity and mortality. Among the recently emerged respiratory pathogens are influenza viruses, coronaviruses, enteroviruses, and adenoviruses. As the genesis of these emerging viruses is not well understood and their detection normally occurs after they have crossed over and adapted to man, ideally, strategies for such novel virus detection should include intensive surveillance at the human–animal interface, particularly if one believes the paradigm that many novel emerging zoonotic viruses first circulate in animal populations and occasionally infect man before they fully adapt to man; early detection at the human–animal interface will provide earlier warning. Here, we review recent emerging virus treats for these four groups of viruses.

See THE DYNAMIC National & International... https://sites.globalhealth.duke.edu/dukeonehealth/     ISSUE 5 August 2018     Recent Publications   A Closer Look at the Emerging Public Health-Burdening Respiratory Viruses By Jane Fieldhouse, MSc For several decades, respiratory virus outbreaks have posed threats to the public at the human-animal interface. In this literature review, Duke One Health team members describe four emerging viruses contributing to a high burden of respiratory tract infections. The review suggests a One Health approach to address potential outbreaks caused by these viruses.   Read more       A Guidebook for Preventing Zoonotic Enteric Parasites Infections Created by the One Health Researchers in Mongolia By Amber Barnes, PhD Zoonotic enteric parasites (ZEP) are a worldwide public health threat. To help the public understand the danger of ZEPs, the One Health Researchers in Mongolia and at Duke University together generated a guidebook to propose ways to prevent ZEP infections.  Read more       Respiratory Virus Surveillance Study Conducted at the Duke University Hospital ED By Julie Zemke Using the 2-stage bioaerosol samplers designed by the National Institute for Occupational Safety and Health (NIOSH), the research team at Duke finds a spectrum of respiratory viruses in the emergency room setting over the course of five months of the Flu season.   Read more     Duke One Health Activities   Bass Connections 2018 Team Conducts a Surveillance Study in Sarawak In Sarawak, Malaysia, members of Duke One Health are working on a cross-cultural collaborative team with researchers from Sibu Hospital and local health authorities to refine surveillance techniques for zoonotic diseases, understand the etiology of such diseases through a One Health perspective, and build the surveillance and diagnostic capacity of local collaborators. Southeast Asia is a hotspot for emerging infectious diseases due to its tropical climate and anthropogenic factors. Increasing and dynamic interactions between humans, animals, and the environment cause outbreaks in novel respiratory viruses that can be devastating to the human and animal communities. There is an evident need to increase surveillance and epidemiological research regarding these diseases at these interfaces.   With support from Bass Connections, a Duke University-wide initiative aiming to promote collaboration in research across disciplines, the team from Duke One Health includes undergraduate students (Gina Kovalik and David Chen), a medical student (Karen Lin) and master’s students (Jessica Choi and Julie Zemke).   Using cutting-edge bioaerosol sampling devices from the National Institute of Occupational Safety and Health (NIOSH), the team is identifying local hubs for novel respiratory pathogen presence and transmission, including swine abattoirs, poultry farms, and schools. By engaging with local stakeholders, including Dr. Toh of Sibu Hospital and Sibu Clinical Research Center, and Mr. Chong of Sibu District Health Office, meaningful partnerships are being formed which may ultimately allow for the creation and maintenance of surveillance and diagnostic capacities throughout Sarawak.   In the photo, Gina Kovalik is examining the NIOSH sampler at a poultry farm during a sampling session.       One Health Training at Duke-NUS in Singapore From July 23 to July 27, 2018, Professor Greg Gray (Duke University), Dr. Emily Bailey (Duke University), Professor Peter Cowen (North Carolina State University), Dr. Betsy Miranda (The Republic of the Philippines), and Dr Kristen Coleman (Duke-NUS Medical School) conducted a five-day workshop at Duke-NUS in Singapore for scholars from Pakistan and the Philippines. The goal of the workshop was to help the international scholars conduct One Health surveillance for novel respiratory viruses which may emerge in their countries at the human-animal interface. The program included an in-depth epidemiological review and laboratory training in detecting influenza viruses, adenoviruses, enteroviruses, and coronaviruses.     Updates on One Health Team Members   <tr style=

Declaration G20 Meeting of Agriculture Ministers 27-28 July 2018, Buenos Aires, Argentina – See AMR VI - ANTIMICROBIAL RESISTANCE (AMR) 31- We emphasize the importance of combating AMR in a One Health approach promoting access to affordable and quality antimicrobials, vaccines and diagnostics, based on well-developed national action plans. We recollect the call of the G20 leaders at the 2017 Hamburg Summit to tackle the spread of AMR in humans, animals and the environment. We will promote interdisciplinary and inter-sectoral approaches, as well as joint actions with the Ministries responsible for human health, animal health, environment and research in order to design national policies and help their implementation by the relevant stakeholders, mainly through One Health-based national action plans. Furthermore, we acknowledge the need: (i) To foster awareness of AMR through dissemination activities and the inclusion in educational curricula for all relevant professions, from initial levels to degree programs. (ii) To encourage public-private cooperation, supporting the scientific community for the research and development of new antimicrobials as well as new technologies (e.g. rapid diagnostics, vaccines and alternative treatments) that help prevent infection and reduce inappropriate antimicrobial use. (iii) To promote good practices, preventive measures and health care in order to reduce the need for and optimize the use of antimicrobials in agriculture while striving to restrict it to therapeutic use alone. To foster the prudent and responsible use of antimicrobials, particularly those important for therapeutic use in humans, taking into account WHOs list of critically important antimicrobials for human health and national lists established on the basis of scientific risk assessments carried out taking into account chapter 6.10 of the OIE Terrestrial Animal Health Code. The prudent and responsible use of antimicrobials does not include their use for the promotion of growth in the absence of a risk analysis conducted in accordance with CAC / GL 77-2011. (iv) To support multi-disciplinary approaches and ongoing implementation of Global Action Plan on Antimicrobial Resistance developed by the World Health Organization with the active contribution of the FAO and OIE in the spirit of One Health. We call on FAO, OIE and WHO to collaborate to improve the prudent use of antimicrobials and on infection prevention to safeguard human and animal health (terrestrial and aquatic), our common food systems, and support scientific collaboration to address knowledge gaps regarding AMR in the environment, in cooperation with other institutions such as UNEP.