One Health Publications

7//2018 Prepared and shared by the One Health Commission     

WHAT IS ProMED? WHO READS ProMED? SOME OF OUR SUCCESSES ProMED SUBSCRIPTIONS   Internet-based reporting system for rapid, global dissemination of information on infectious disease outbreaks and acute exposures to toxins in humans, animals, and plants   Free to everyone, open-access, and accessible via email, website, Twitter, Facebook, or app   One of the early innovators using non-traditional & informal information sources   Apolitical, transparent, committed to One Health   Publishes infectious disease reports on a real-time basis around the clock   A program of the International Society for Infectious Diseases (ISID)

The July-September 2018 bulletin can be downloaded from: http://www.fao.org/3/CA0353EN/ca0353en.pdf   The Early Warning Early Action (EWEA) report on food security and agriculture is developed by the Food and Agriculture Organization of the United Nations (FAO). It provides a quarterly forward-looking analysis of major disaster risks to food security and agriculture, specifically highlighting: • potential new emergencies resulting from imminent disaster threats • new developments in countries already affected by protracted crises which are likely to cause a further deterioration of food insecurity

Penn One Health goes abroad Penn: Office of University Communications Ferrara found he could combine his love for animals with a public-health perspective through One Health, which analyzes and addresses health ... ...Ferrara found he could combine his love for animals with a public-health perspective through One Health [also see www.onehealthinitiative.com], which analyzes and addresses health issues at the intersections of human, animal, and environmental health. ... “The One Health perspective is inherently interdisciplinary,” ... He says he also hopes his trip to Nepal will serve as a model for future projects and sees no bounds for One Health’s potential at Penn. Eventually, Ferrara wants to establish a One Health Center on campus where students and researchers can foster ideas and develop intervention projects.” ...  “It’s really about the One Health perspective,” he says. “Maybe we have our separate expertise, but One Health is a vehicle to bring people together to tackle more complex, interdisciplinary issues.” ...”

  About this Article, Published in Issue #0618 SEE:  https://thepathologist.com/issues/0618/the-astropathologist/ The Pathologist’s June issue covers what we gain from death! We speak to a team of experts behind human decomposition facilities to dig into how the dead can breathe life into research and provide vital forensic clues. We also delve into measuring the risk of Alzheimer’s disease, detecting malaria in mosquitoes with NIRS, how AI can aid healthcare, using methylation biomarkers to assist prognosis, the lab of the future, and much more. Plus, we sit down with astronaut and veterinary pathologist Richard M. Linnehan to discuss his career on and off the planet. Sitting Down With… [Dr.] Richard M. Linnehan, Veterinarian/Astronaut, Houston, USA “... When you look down at our planet from space, you realize that everything that seems so big and infinite… isn’t. It made me realize just how important the concept of “One Health” is. For instance, I’m a veterinarian, so I do comparative pathology – avian, reptile, amphibian, mammalian, human, even invertebrate – but most healthcare professionals focus only on humans. “One Health” brings us back to the idea that it’s all connected. Disease entities don’t stick to a single organism or environment; they move between them. The planet is smaller than we think. It’s a closed ecosystem, and everything that lives will eventually, in some way, affect everything else. ...” June 2018   What initially prompted you to study veterinary pathology? I was always interested in disease processes and epidemiology, but what sparked my interest in veterinary medicine was working for a local equine and large animal veterinarian in high school. I thought it was really cool that a human could actually help animals that big. I was interested in human medicine, too, but I was so intrigued by the veterinary side – especially exotic animals – that I decided to take that route. I did my veterinary residency in comparative pathology and exotic animal medicine, and then did research and clinical work with zoo animals for several years. My main interest, even then, was in marine mammals and related ecosystems. I met the head of the US Navy’s marine mammal program while in veterinary school, and I wanted to be the program’s main veterinarian. Even though I had stayed in touch and geared my residency and extracurricular activities toward marine mammal work, I couldn’t believe it when I got the job! The program involved training teams of sea lions and dolphins to perform underwater searches – they were much better than human divers. The animals were never in danger, of course; we just relied on them to detect and report potential hazards. In fact, they were better taken care of medically and nutritionally than most people! We also did some pretty cool research – studies on reproduction, longevity, nutrition, and many other things. How did that lead to a career as an astronaut? Before I applied to veterinary school, the only other thing I had ever wanted to be was a fighter pilot. I was accepted into the Air Force and veterinary school at the same time, and my advisor convinced me to choose the latter. During my studies, I used to watch the shuttle launches and ask myself, “How can I still fly?” And I figured that, if the space program was sending up mission specialists, doctors, physicists, and geologists, they’d need a veterinarian as well. I interviewed with them (for which I can thank my experience as a deploying military marine mammal veterinarian) and, in 1992, they called me to say, “Would you like to be an astronaut?” Well – of course I would! When you look down at our planet from space, you realize that everything that seems so big and infinite… isn’t. It made me realize just how important the concept of “One Health” is. For instance, I’m a veterinarian, so I do comparative pathology – avian, reptile, amphibian, mammalian, human, even invertebrate – but most healthcare professionals focus only on humans. “One Health” brings us back to the idea that it’s all connected. Disease entities don’t stick to a single organism or environment; they move between them. The planet is smaller than we think. It’s a closed ecosystem, and everything that lives will eventually, in some way, affect everything else. What was your role on your missions? My first mission, STS-78, was a life and microgravity sciences mission in the Spacelab where we looked at how various biological processes work in space. We looked at the differences in how biological systems function in zero or microgravity versus normal gravity. Everything that has ever lived on Earth has evolved in a 1 G gravity field, so when you take that away, how do things respond? The second flight – STS-90, or Neurolab – was much more involved. We were looking at nervous system disturbances brought on by spaceflight. We had a vast array of animals – crickets, rodents, even oyster toadfish. Fish are kind of wild because their neutral buoyancy means that they live in a pseudo-microgravity environment – but they rely on gravity to tell them up from down. So how do they maintain buoyancy and navigation in space? We also liked to joke that we had four big primates on board on whom we performed most of our experiments – us. I was pleased to have the opportunity to use my veterinary degree and pathology training to help the future survival of humanity. If we can’t figure out how to keep humans healthy and strong in space, then we’re not going to go. We won’t travel long distances to other planets, because by the time we get there, we’re going to be so unhealthy and so discombobulated that we won’t be able to function. I hope our operational studies will one day help humans take to the stars. My final two missions were not life sciences-related, and allowed me to venture into the world of spacewalking. On STS-109, we rendezvoused with, repaired, and upgraded the Hubble Space Telescope. That was an awesome flight experience and a great mission. My last flight, STS-123, was to the International Space Station, where I and my spacewalk team helped build the space station. We installed the Japanese laboratory, called Kibo, and a giant robot called the Special Purpose Dexterous Manipulator that moves around the station and replaces worn-out parts. What do you think is the most underrepresented aspect of pathology? I think it’s comparative pathology – the link between disease processes in humans, animals, and the environment. We haven’t thought about it as much as we should because we’re too focused on our own species, so we don’t always consider that the same organisms and errors cause problems to other species as well, even though the presentations may be different to our own. We must remember that it’s all interrelated. Permission to reprint granted to the One Health Initiative website July 8, 2018 by: Michael Schubert, Editor | Texere Publishing Limited, t: 01565 745 193 | www.thepathologist.com

June 8, 2018—American Public Health Association (APHA) Organizations’ letter to U.S. Congress Appropriations Committee leaders in support of strong investments in antimicrobial resistance in FY 2019 appropriations bills using ONE HEALTH APPROACH   SEE: https://goo.gl/kaai5a 3rd paragraph, “The report also highlights the need for continued and robust funding for AMR given that nationwide testing last year documented 221 cases of so-called “nightmare bacteria,” that can spread resistance to last-resort antibiotics. Robust, sustained investment in multi-agency One Health efforts is vital to combat AMR domestically and globally including prevention, antimicrobial stewardship, surveillance and data collection, research, and development of urgently needed new products including antimicrobial drugs, diagnostics, vaccines and alternative treatments.” 11th paragraph, “Food and Drug Administration and US Department of Agriculture Experts agree that a One Health approach, including both human and animal health, is essential for combating antimicrobial resistance. We urge funding of $54 million for the Combating Antibiotic Resistant Bacteria initiative at FDA to support FDA’s efforts to address public health concerns associated with antimicrobial drug use in animals, and better protect antibiotic effectiveness for both human and animal populations. This funding is needed now more than ever, with estimates that antibiotic use in humans and livestock will rise by 50% before 2030. FDA would be able to better collaborate with consumers, producers, veterinarians, and other agencies to monitor AMR through the National Antimicrobial Resistance Monitoring System (NARMS) as well as other initiatives by the FDA Center for Veterinary Medicine to address AMR.” Notably, see list of prominent organizational signatories: Accelerate Diagnostics, Inc. AdvaMedDx Alliance for Aging Research Alliance for the Prudent Use of Antibiotics American Academy of Pediatrics American Association of Avian Pathologists American Association of Bovine Practitioners American Public Health Association American Society of Transplant Surgeons American Society of Tropical Medicine & Hygiene American Thoracic Society American Veterinary Medical Association Antibiotic Resistance Action Center, the George Washington University Antimicrobials Working Group (Amplyx Pharmaceuticals, Aridis Pharmaceuticals, Arsanis Inc., Cidara Therapeutics Inc., ContraFect Corporation, Iterum Therapeutics Ltd., Melinta Therapeutics Inc., Motif Bio plc, Nabriva Therapeutics US Inc., Paratek Pharmaceuticals Inc., SCYNEXIS Inc., Spero Therapeutics, Inc., T2 Biosystems Inc., Theravance Biopharma U.S. Inc., Viamet, Vical Incorporated, and Zavante Therapeutics Inc.) Association for Professionals in Infection Control and Epidemiology Association of American Veterinary Medical Colleges Association of State and Territorial Health Officials Becton Dickinson and Co. (BD) bioMerieux Biotechnology Innovation Organization (BIO) Center for Disease Dynamics, Economics & Policy Center for Foodborne Illness Research and Prevention   Clinician Champions in Comprehensive Antibiotic Stewardship   Consumer Federation of America Council of State and Territorial Epidemiologists   Da Volterra   Duke Center for Antimicrobial Stewardship and Infection Prevention   Emory Antibiotic Resistance Center   Food Animal Concerns Trust GlaxoSmithKline Global Health Council Health Care Without Harm HIV Medicine Association Immune Deficiency Foundation   Infectious Diseases Society of America   Johns Hopkins Center for a Livable Future   Making-A-Difference in Infectious Diseases   March of Dimes   National Association of County and City Health Officials National Association of Pediatric Nurse Practitioners   NovaDigm Therapeutics, Inc. Pediatric Infectious Diseases Society Peggy Lillis Foundation   Sepsis Alliance Society of Critical Care Medicine   Society of Infectious Diseases Pharmacists Spero Therapeutics   The Fecal Transplant Foundation   The Gerontological Society of America   The Pew Charitable Trusts   The Society for Healthcare Epidemiology of America   The Society of Critical Care Medicine Treatment Action Group   Trust for Americas Health  

Guidelines for Inspection of Companion and Commercial Animal Establishments  “Various establishments exist in which animals are held for a variety of reasons. Historically, the management and inspection of animals in commerce and in private keeping have involved a considerable degree of arbitrary evaluation based on the personal experience of the vendor, keeper, advisor, or inspector. Accordingly, relevant protocols and standards are subject to considerable variation. Relatedly, diversity of traded and privately kept species generates significant challenges for those responsible for facility management and inspection alike. Animal welfare and public health and safety are constant and major concerns that require objective methodologies to monitor and control. This report focuses on establishments concerned with the boarding, breeding, storage, vending or handover of animals intended for human “companions” or “pets”, and aims to provide universal objective information for essential husbandry, inspection protocols and an allied inspection assessment tool for scoring establishments.” Citation: Warwick C, Jessop M, Arena P, Pilny A and Steedman C (2018) Guidelines for Inspection of Companion and Commercial Animal Establishments. Front. Vet. Sci. 5:151. doi: 10.3389/fvets.2018.00151  Link: https://doi.org/10.3389/fvets.2018.00151 and https://www.frontiersin.org/articles/10.3389/fvets.2018.00151/full NOTE: Also see ‘Health Initiative Targets Exotic Pet Keepers’ http://www.onehealthinitiative.com/news.php?query=Health+Initiative+Targets+Exotic+Pet+Keepers+  

  ISSUE 4 July 2018     Recent Publications   Using a One Health Approach, Duke Researchers and Collaborators in China Find Evidence for Cross-species Influenza A Transmission Within Swine Farms By Laura Borkenhagen, MSc In an effort to better understand the influenza A virus transmission between humans and pigs, Duke University researchers and collaborators from multiple organizations in China conducted a large prospective study of pigs, pig workers, and six pig farms. Their important work is one of the few to be conducted interdisciplinary way. It was recently published in the high impact journal Clinical Infectious Diseases.     Read more       Duke One Health Mongolian Team Identifies Potential Risk Factors for Zoonotic Disease Transmission Among Horse and Camel Herder Households By Lexi Sack, DVM In this pilot study, One Health D43 team 2 researchers from Duke University and The Institute of Veterinary Medicine in Mongolia conducted a survey of 131 households to determine the risk factors for transmitting zoonotic disease in households caring for horses and camels. Public health concerns may arise from using dried manure for fuel and drinking unprocessed river water.   Read more       Duke and University of Iowa Experts Point Out Novel Pathogen Threats Emerging from Chinese Swine Farms By Jane Fieldhouse, MSc In the high impact journal Lancet Infectious Diseases, Professor Gregory Gray from Duke University and Professor & former dean James Merchant from the University of Iowa College of Public Health commented upon emerging pathogens threats from China’s growing swine industry.  They argue that heightened biosafety and biosecurity measures are immediately needed to prevent future novel pathogen outbreaks.   Read more     Duke One Health Activities   Two Duke Global Health Institute Rising Second-Year Master’s Students Conduct Fieldwork Research in Borneo Island of Malaysia for 10 Weeks   Juliana Zemke is conducting a surveillance of arboviruses in Sarawak, Malaysia. Arbovirus surveillance is vastly under-resourced, relying heavily on passive surveillance systems in Malaysia. The current diagnostic methods for patients presenting with dengue-like infections may misconstrue cases of dengue, chikungunya, and Zika virus infections, given that all three arboviruses have similar clinical manifestations. In this pilot study, Juliana aims to gather evidence to determine the prevalence of dengue, chikungunya, and Zika viruses among patients with dengue-like infections at Sibu and Kapit hospitals. She also plans to validate the clinical value of the T-Cor 8 Real-Time PCR Thermocycler (Tetracore Inc., USA) in detecting these viruses.       Jessica Choi is conducting a field trail of new diagnostics help the local physicians and laboratorians in Kapit more rapidly diagnose a dangerous bacterial disease, melioidosis. The current diagnostics are limited by the time and inaccuracy. For melioidosis patients, the administration of antibiotics is critical as the bacteria causing melioidosis, Burkholderia pseudomallei, may lead to fatal conditions if left untreated. The rapid diagnostic tool developed by the University of Nevada team, which uses lateral flow immunoassay, may be a promising solution for the Kapit communities. This is the first time that this novel tool is being validated in a melioidosis-epidemic site. Jessica hopes that the new diagnostics will provide a better care for the affected individuals and that the Kapit medical team will build confidence when facing the future melioidosis patients.    <span style="font-family: Tim

20% discount off with this flyer! Survival One Health, One Planet, One Future By George R. Lueddeke, PhD Currently expected released on 19 September, 2018  

  North Carolina researchers earn Global One Health Award Todays Veterinary Business Magazine (press release) (blog) The award, presented by the World Small Animal Veterinary Associations One Health Committee, went to Ed Breitschwerdt, DVM, DACVIM, of the ...  

5th International One Health Congress – a reflection BMC Blogs Network (blog) One Health regards the health of humans, animals and the environment as being interconnected, so when we look at human health we must also ...

  Superbugs: MEPs advocate further measures to curb use of antimicrobials The European Sting Diseases are transmitted from people to animals and vice versa, and that is why we support the holistic approach of the One Health initiative” said ...  

See the Gear CDCs Disease Detectives [epidemiologists] Use in the Field Centers for Disease Control and Prevention (CDC) sent this bulletin at 06/15/2018 11:45 AM EDT https://content.govdelivery.com/accounts/USCDC/bulletins/1f75d19

34th World Veterinary Association Congress 5-8th May 2018, Barcelona, Spain Short summary of WVA activities during WVC2018 The 34th World Veterinary Association Congress took place on 5th- 8th May 2018, in Barcelona, Spain, under the Honorary Presidency of the Spanish Royal Family. With participation of delegates from 67 countries, this new edition delivered an excellent scientific program covering different fields of veterinary medicine from innovation and research, veterinary public health to vast aspects of clinical practice.   “The Opening Ceremony of the WVAC2018 was opened by the presidents of the College of Veterinarians of Barcelona, General Council of the Spanish Colleges of Veterinarians and the World Veterinary Association welcoming the delegates. The Opening Ceremony continued with presentations by the Secretary General of the Spanish Ministry of Agriculture and Food and the Minister of Health, Social Services and Equality, Mrs. Dolors Montserrat i Montserrat. Both highlighted the importance of the One Health concept and the major role of the veterinary profession for the Spanish and European society. Those topics were also highlighted by Vytenis Andriukaitis, the EU Commissioner for Health & Food Safety who also emphasized the importance of the profession in Europe for the wellbeing of society and welfare of animals and the need for collaboration with other health professionals. ...”        

<!-- --> 5th International One Health Congress, 22-25 June 2018The final programme of the worlds premier One Health congress is now available. Registration is still possible! Check the updated program or register for the congress. <!-- --> World Bank One Health Operational Framework The World Bank has released an Operational Framework for Strengthening Human, Animal and Environmental Public Health Systems at their interface (“One Health Operational Framework”). This new framework, developed in partnership with EcoHealth Alliance, aims to provide a basis for understanding and implementing a One Health approach in global and country investments. Building on World Bank’s prior “People, Pathogens, and our Planet” reports, it examines the strategic context, rationale and case for investing in One Health, provides an inventory of tools and other resources from the human health, agriculture, environment and disaster risk reduction sectors to facilitate multi-sectoral coordination, and incudes technical guidance for appropriate One Health entry points and operations along the prevent-detect-respond-recover spectrum of preparedness.Free download <!-- --> <Paper> Core Competencies in One Health Education: What Are We MissingEnsuring appropriate education and training across human, animal, and environmental health to respond to today’s public health threats is critical - but not easy. The growing trend in One Health educational programs is an important step, though it has been unclear if and how core competencies are applied.  The authors of the newest National Academy of Medicine (NAM) Perspectives paper assess the evolution of existing One Health core competencies and provide an analysis of One Health degree programs across the US including key areas represented, knowledge gaps, and recommended improvements for preparing future One Health leaders.More information <!-- --> Your feedback is requested on The Sustainability of One Health CoordinationThe USAID-funded Preparedness and Response (P&R) Project is conducting a pairwise survey to better understand the factors that make One Health coordination and collaboration sustainable. Preliminary results from the survey will be shared at the upcoming International One Health Congress in Saskatoon during the SPI track session “Making One Health operational: the barriers to change glimmers of hope.” Please take a few minutes to participate in the pairwise wiki survey here. If you have any questions on the survey or would like to see the final report, please feel free to contact Robert Salerno at Robert_Salerno@dai.com.  

Old-World Virus, New Tricks: Inside Kerala’s Quest To Contain The Deadly Nipah Virus SEE in full: https://www.huffingtonpost.in/2018/05/24/old-world-virus-new-tricks-inside-kerala-s-quest-to-contain-the-deadly-nipah-virus_a_23443118/   ...The animal health department is collecting samples of rats, bats and other species to find the Nipah reservoir host. Samples are being analyzed by the National Institute of High Security Animal Diseases in Bhopal. This is a very good example of the One Health approach, where animal and human health and public health, the administration, state government, central government all coming together and containing this outbreak, said Arunkumar of Manipal.   “... Almost three-fourths of all diseases that afflict humans originate in animals, and a new zoonosis has been emerging or re-emerging every year. SARS, MERS-CoV, Ebola and H5N1 have all sparked fear and cost the global economy tens of billions of dollars.   In the early 2000s, a trio of scientists in the U.S. recognized that animal and human health are intricately connected. They advocated for a One Health approach that integrates human health, animal health, agriculture and the environment to respond to and avoid outbreaks. Few nations have so far taken a pro-active approach to stopping animal-to-human transmission before they happen, according to various studies. Health systems, including Indias, are focused instead on stopping pandemics, through quarantine, drugs and vaccines. The animal health department is collecting samples of rats, bats and other species to find the Nipah reservoir host. Samples are being analyzed by the National Institute of High Security Animal Diseases in Bhopal.   Some aspects of the approach found takers in India in 2005 following an H5N1 avian flu outbreak. For the first time, animal, environment, wildlife and human health departments coordinated to monitor and develop avian influenza contingency plans. South Asia, and India in particular, is a hotspot for emerging and re-emerging zoonosis due to its tropical forests, high biodiversity, high poverty rate and a large number of people living in close proximity to animals.   Since then, the Indian government has been setting up a network of virus detection labs. With help from the U.S. Centers for Disease Control and Prevention, it has set up more Biosafety Level- 3 and 4 labs where scientists can safely study the most dangerous viruses. ...”

The One Health Initiative: The Collaboration between Human and Animal Medicine Written by Carol Petersen, RPh, CNP – Women’s International Pharmacy The idea of a “One Health” organization started with the American Veterinary Medical Association (AVMA). In 2006, they created a multidisciplinary task force of representatives from different health professions to explore the possibility of working together on solutions and treatments. The resulting One Health Initiative promotes active collaboration among professionals caring for animals and professionals caring for humans. Their vision statement says that they are “dedicated to improving the lives of all species, human and animal, through the integration of human medicine, veterinary medicine and environmental science.” ... SEE: https://www.womensinternational.com/one-health-initiative/.    

Overview of Zoonotic Diseases in Turkey: The One Health Concept and Future Threats ABSTRACT Zoonotic infections are globally important diseases and lead to huge economic losses in both low- and middle-income and high-income countries. Global warming, environmental and ecological changes, illegal movement of animals and humans, regional civil wars, and poverty are predisposing factors for the emergence of zoonotic infections and their distribution worldwide; they are also a big threat for the future. In addition, environmental pollution and antimicrobial resistance are immense serious threats and dangers to prevent and control zoonotic infections. The natural location of Turkey allows many emerged or re-emerged infections with zoonotic characteristics by animal movements, such as bird immigrations, and by human movements due to civil wars as seen with regional refugees. Numerous zoonotic diseases, including 37 bacterial, 13 fungal, 29 viral, 28 parasitic (3 trematodes, 7 cestodes, 10 nematodes, and 8 protozoan), and totally 107 infections, have been reported from Turkey to date. Additionally, many ectoparasitic zoonoses within 15 different arthropod groups and one leech infestation have been reported from Turkey to date. The “One Health” initiative is particularly relevant for developing strategies to combat zoonotic diseases. In this article, we review the occurrence of zoonotic diseases in man and animals in Turkey in the light of the “One Health” perspective. http://www.turkiyeparazitolderg.org/sayilar/71/buyuk/39-80.pdf      

One Health Day 2018 Launch Press release One Health Day is an international, global campaign coordinated by the One Health Commission www.onehealthcommission.org, the One Health Initiative Autonomous pro bono Team www.onehealthinitiative.com and the One Health Platform Foundation www.onehealthplatform.com.

http://mbio.asm.org/content/9/3/e00909-18 Emergence and Evolution of Novel Reassortant Influenza A Viruses in Canines in Southern China ABSTRACT The capacity of influenza A viruses (IAVs) to host jump from animal reservoir species to humans presents an ongoing pandemic threat. Birds and swine are considered major reservoirs of viral genetic diversity, whereas equines and canines have historically been restricted to one or two stable IAV lineages with no transmission to humans. Here, by sequencing the complete genomes of 16 IAVs obtained from canines in southern China (Guangxi Zhuang Autonomous Region [Guangxi]) in 2013 to 2015, we demonstrate that the evolution of canine influenza viruses (CIVs) in Asian dogs is increasingly complex, presenting a potential threat to humans. First, two reassortant H1N1 virus genotypes were introduced independently from swine into canines in Guangxi, including one genotype associated with a zoonotic infection. The genomes contain segments from three lineages that circulate in swine in China: North American triple reassortant H3N2, Eurasian avian-like H1N1, and pandemic H1N1. Furthermore, the swine-origin H1N1 viruses have transmitted onward in canines and reassorted with the CIV-H3N2 viruses that circulate endemically in Asian dogs, producing three novel reassortant CIV genotypes (H1N1r, H1N2r, and H3N2r [r stands for reassortant]). CIVs from this study were collected primarily from pet dogs presenting with respiratory symptoms at veterinary clinics, but dogs in Guangxi are also raised for meat, and street dogs roam freely, creating a more complex ecosystem for CIV transmission. Further surveillance is greatly needed to understand the full genetic diversity of CIV in southern China, the nature of viral emergence and persistence in the region’s diverse canine populations, and the zoonotic risk as the viruses continue to evolve. IMPORTANCE Mammals have emerged as critically underrecognized sources of influenza virus diversity, including pigs that were the source of the 2009 pandemic and bats and bovines that harbor highly divergent viral lineages. Here, we identify two reassortant IAVs that recently host switched from swine to canines in southern China, including one virus with known zoonotic potential. Three additional genotypes were generated via reassortment events in canine hosts, demonstrating the capacity of dogs to serve as “mixing vessels.” The continued expansion of IAV diversity in canines with high human contact rates requires enhanced surveillance and ongoing evaluation of emerging pandemic threats.