One Health Publications

Ranking the risk of animal-to-human spillover for newly discovered viruses

April 12, 2021


The recent emergence and spread of zoonotic viruses, including Ebola virus and severe acute respiratory syndrome coronavirus 2, demonstrate that animal-sourced viruses are a very real threat to global public health. Virus discovery efforts have detected hundreds of new animal viruses with unknown zoonotic risk. We developed an open-source risk assessment to systematically evaluate novel wildlife-origin viruses in terms of their zoonotic spillover and spread potential. Our tool will help scientists and governments assess and communicate risk, informing national disease prioritization, prevention, and control actions. The resulting watchlist of potential pathogens will identify targets for new virus countermeasure initiatives, which can reduce the economic and health impacts of emerging diseases.


The death toll and economic loss resulting from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic are stark reminders that we are vulnerable to zoonotic viral threats. Strategies are needed to identify and characterize animal viruses that pose the greatest risk of spillover and spread in humans and inform public health interventions. Using expert opinion and scientific evidence, we identified host, viral, and environmental risk factors contributing to zoonotic virus spillover and spread in humans. We then developed a risk ranking framework and interactive web tool, SpillOver, that estimates a risk score for wildlife-origin viruses, creating a comparative risk assessment of viruses with uncharacterized zoonotic spillover potential alongside those already known to be zoonotic. Using data from testing 509,721 samples from 74,635 animals as part of a virus discovery project and public records of virus detections around the world, we ranked the spillover potential of 887 wildlife viruses. Validating the risk assessment, the top 12 were known zoonotic viruses, including SARS-CoV-2. Several newly detected wildlife viruses ranked higher than known zoonotic viruses. Using a scientifically informed process, we capitalized on the recent wealth of virus discovery data to systematically identify and prioritize targets for investigation. The publicly accessible SpillOver platform can be used by policy makers and health scientists to inform research and public health interventions for prevention and rapid control of disease outbreaks. SpillOver is a living, interactive database that can be refined over time to continue to improve the quality and public availability of information on viral threats to human health.

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Global One Health initiative awarded CDC Cooperative Agreement to expand capacity and strengthen public health systems in Ethiopia

April 9, 2021

Apr 7, 2021

Source: CDC

The Ohio State University Global One Health initiative (GOHi) has been awarded $5.61 million in funding from the Centers for Disease Control and Prevention (CDC) to fight the COVID-19 pandemic and bolster Ethiopia’s public health system capacity for small- and large-scale disease outbreaks and emergencies.

Since 2009, GOHi has been on the front lines in Ethiopia working with in-country partners to strengthen capacity using a One Health approach—one that brings together multiple disciplines working globally to address the spread of disease, promote health and emphasize the connection among humans, animals, plants and the environment.

As new diseases emerge, the need for health system preparedness across the globe is vital for nations to prevent spread of pathogens, detect and report epidemics, and respond to and mitigate the spread of those epidemics. The current COVID-19 pandemic urgently underscored these needs. Under-preparedness in one country, is a global risk to all.






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Why India needs a ‘One Health’ vision to tackle the crisis caused by the pandemic

April 7, 2021

‘One Health’ initiatives, by their multidisciplinary nature, entail working across ministries and navigating tacit institutional hierarchies and allocating leadership roles. This holistic view of health is important in the post-pandemic scenario.




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One Health Initiative team member honored by University of Florida (UF) Alumni Association

April 6, 2021

Helena Chapman
BS ’03, MPH ’05, Ph.D ’16 |  Arlington, VA

TITLE: Associate Program Manager, Health and Air Quality Applications, NASA Applied Sciences Progam
Booz Allen Hamilton/NASA
Government Services

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Minor in One Health | Mel and Enid Zuckerman College of Public Health

April 5, 2021

Mel and Enid Zuckerman College of Public Health – University of Arizona

The groundbreaking field of One Health – understanding how human health is deeply interconnected with animal health and environmental health 


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Vaccination as a Control Tool in Bovine Tuberculosis: Social Media Monitoring to Assess Public Response to Government Policy Development and Implementation

April 4, 2021

By  DocWire News Featured Reading – 
Vaccine hesitancy does not only concern human vaccines but incorporates One Health policies also; including vaccination of cattle and badgers as part of the government’s bovine tuberculosis eradication strategy for England. Both digital and social media can propagate healthcare misinformation and thus affect vaccine policy support. The use of social media monitoring to understand real-time public perceptions of One Health policies is crucial to identify misinformation and address public concerns appropriately to achieve successful policy implementation. Digital and social media data surrounding two government announcements regarding the bovine tuberculosis eradication strategy for England were collected and screened using the Meltwater media monitoring platform. Communication patterns were studied using InfraNodus. Twitter analysis was conducted to identify key influencers, public engagement, and trending communications. Online social media activity increased rapidly after each announcement. Initially, badger culling took primary public concern and major influencers were identified. Cattle vaccination dominated discussion after the second announcement, with public perception being influenced by increased online activity from news sites, animal welfare charities, governmental bodies, and medical professionals. The greatest ambiguity towards the strategy was detected within farming communities, with the main disparity existing between cattle vaccination and badger culling opinions. Social media monitoring has potential use in surveying public perception of government policy, both prior to, and after implementation to identify and address areas of miscommunication and misinformation to improve public support for One Health policies. View Full-Text

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One Health Commission

March 27, 2021

Global Events Since 2001

We even post significant One Health past events to create a repository of how the ‘paradigm shift’ has progressed in the past two decades. If you know of …

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A Call for One Health in Medical Education: How the COVID-19 Pandemic Underscores the Need to Integrate Human, Animal, and Environmental Health

March 27, 2021

“ …  Preventing future pandemics will require a transdisciplinary One Health approach, and physicians should be prepared to participate in these discussions while advocating for One Health initiatives for the benefit of their current and future patients. Integration of One Health education into medical school curricula will also prepare future physicians for other complex and urgently important health issues such as climate change, antimicrobial resistance, and the impact of biodiversity loss. As the consequences of the COVID-19 pandemic persist, education in One Health must become a priority; it is essential to break down the conventional disciplinary silos of human medicine, veterinary medicine, environmental health, public health, and the social sciences, so that future health crises can be prevented and mitigated collaboratively.”



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One Health for One Planet: How to Address 21st Century Education Challenges – Impakter

March 23, 2021

We have been experiencing the worst global pandemic in over a century and it has brought the world economy to its knees. Now we need to map out the path to recovery, and in doing so, we have become aware of the incredible challenge of how to do better in the future. A lot will need to change for our post-COVID world to be sustainable and protected from another pandemic hitting us through an animal vector. In this article, I explore the most important change that needs to be made and that involves addressing 21st Century education challenges in a One Health manner.

The starting point is for us to recognize that the interface between animal-human-environmental health is not rhetoric but reality. The concept of One Health, which once sat on the periphery of the academic world, has now taken full center. This means that civil society, political decision processes, and the private sector need to embrace this fundamental notion. 

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