One Health Publications

A ‘One Health’ approach

“One of the main drivers of drug-resistant pathogens is the misuse and overuse of antibiotics, both in humans and animals,” Professor Blaskovich said.

“Nearly two-thirds of all antibiotics used worldwide in 2017 were for animals, and these are often used promote growth or prevent diseases rather than treat infections.

“It is imperative that treatments for livestock and companion animals don’t overlap with equivalent human therapeutics to reduce transmission of resistance across sectors.”

The Centre brings together multidisciplinary teams and applies a ‘One Health’ approach to antimicrobial resistance to acknowledge the interconnections between humans, animals, and the environment.

“… The study illustrates the growing relevance of the One Health concept, coalescing aspects of public health, veterinary health and conservation.

Several student One Health projects are already underway at the IIC, which plans to work with conservation partners to increase their availability in the future. One Health opportunities will provide additional avenues of research to students in W&M’s popular pre-medicine and kinesiology programs. …”

Policies for Equitable Access to Health [PEAH]

IN A NUTSHELL

Editor’s note Under One Health perspective, a live PDF here PEAH just received from our acknowledged partner Dr. George Lueddeke.

Originally from Canada, now residing in the United Kingdom, George Lueddeke PhD MEd Dipl.AVES (Hon.) is an education advisor in Higher, Medical and One Health education and global lead of the International One Health for One Planet Education initiative (1 HOPE) in association with national, regional, and global organisations

By George Lueddeke, PhD

Consultant in Higher, Medical, and One Health Education

Global Lead – International One Health for One Planet Education initiative (1 HOPE)

Among One Health Journals – “Open Access” – One Health Initiative …

One Health & Implementation Research  [https://www.oaepublish.com/ohir]

Please see four (4) new articles published this year including:

 –Faster, higher, stronger: the evolution of clinical perspectives on pan-TB

Corresponding author: Prof.  Hongzhou Lu, the president of Shenzhen Third People’s Hospital, a fellow of the American College of Microbiology. And he is listed in Changjiang Scholars Program by the Ministry of Education of the People’s Republic of China, the Thousand and Ten Thousand Talent Program and National Outstanding Middle-aged and Young Experts.

-Viral sequencing to inform the global elimination of dog-mediated rabies – a systematic review

Corresponding author: Dr. Kirstyn Brunker, Graham Kerr building, School of Biodiversity, One Health & Veterinary Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow.

–Epidemiological survey of accidents with venomous animals treated at the Regional Hospital of Bom Jesus, Piauí, Northeast Brazil

Corresponding author: Dr. Lilian Silva Catenacci, Postgraduate Program in Postgraduate Studies in Technologies Applied to Animals of Regional Interest, Federal University of Piaui

–Alaskapox mystery solved by a one health approach

About the author: Prof. Daniel R. Lucey, a clinical professor of medicine at Dartmouth Geisel School of Medicine.

Provided by:

 Phoebe Zhao, Science Editor

One Health & Implementation Research Journal

The Pandemic Prevention Leadership Initiative (PPLI) (2024-25) is designed to build capacity and strengthen collaborative approaches in Southeast Asia to address threats to global health security and biodiversity conservation posed by unregulated trade in wildlife species. Through its activities, the initiative will promote the development of a network of leaders from multiple disciplines able to work together to address the spillover of high-consequence pathogens (HCPs) in Southeast Asian live animal markets and supply chains, from prevention through response.  The PPLI promotes capacity strengthening in early to mid-career professionals by incorporating the Pandemic Prevention Fellows Program which utilizes a cohort approach and case-based training to directly support the development of a multidisciplinary network of leaders across the Southeast Asia region to address the ever evolving and expanding global health and security threats related to zoonotic spillover of HCPs and associated practices impacting wildlife populations.  The Wildlife Conservation Society (WCS), EpiEcos, and the University of California – Davis (UCD), as well as regional subject-matter experts, will deliver the case-based training program and support the development and implementation of individual projects led by Pandemic Prevention Fellows.

Please see:

https://oneworldonehealth.wcs.org/Initiatives/Pandemic-Prevention-Leadership-Initiative.aspx

https://oneworldonehealth.wcs.org/Training/Pandemic-Prevention-Leadership-Initiative.aspx

Online application-

https://docs.google.com/forms/d/e/1FAIpQLSd4R0o9exxNI3hfKg4Tt7gPOWp0fAANKgn8rLU3VA-VgHYdrA/viewform

Provided by:

Dibesh Karmacharya, PhD

Regional Project Coordinator

Pandemic Prevention Leadership Initiative (PPLI)

Wildlife Conservation Society- Health

E: dkarmacharya@wcs.org

W: +977-9851110329

WCS One World One Health Home Page

One World – One Health > Training > Pandemic Prevention Leadership Initiative (wcs.org)

WIPO leads the development of a balanced and effective global intellectual property ecosystem to promote innovation and creativity for a better and more sustainable future.

“ … Global South Leading the Way in One Health

Another panel discussion explored the role of the Global South in driving innovation for One Health, an approach that integrates human, animal, and environmental health to prevent pandemics. Panelists noted that discussions on One Health is focusing on zoonotic diseases. Effective interventions require community engagement and context-specific solutions that consider local consumption patterns and human-animal-livestock interfaces. Public-private partnerships and private sector innovations in sampling and surveillance were identified as crucial for advancing One Health. The discussion emphasized that overcoming the challenges of One Health requires not just technical solutions but also political commitment and cross-stakeholder collaboration.

• Find out more about how WIPO is working on One Health. …”

The ‘One Health’ approach that integrates the health of people, animals and the environment, is crucial for addressing complex health challenges such as zoonotic diseases and antimicrobial resistance

“… Doshi explains the World Health Organization’s (WHO) One Health plan, which according to WHO, is an “integrated, unifying approach that aims to sustainably balance and optimize the health of people, animals and ecosystems.”¹  …”

“… Finally, FDA issuing aOne Healthstrategy to mitigate the impact of H5N1 HPAI virus (Objective 3). One Health interventions to prevent, control, or eliminate H5N1 HPAI in animals, milk, and the environment are under development; for example, strategies to decrease the impact of H5N1 HPAI, interventions to prevent or control spread of H5N1 HPAI, and alternative viral inactivation and disposal methods for discarded milk.”

One Health Fact Sheet‎

CDC’s One Health Office recognizes that the health of people is connected to the health of animals and our shared environment. A One Health approach encourages collaborative efforts of many experts (like disease detectives, laboratorians, physicians, and veterinarians) working across human, animal, and environmental health to improve the health of people and animals, including pets, livestock, and wildlife.

Read More

Provided by:  *George Lueddeke PhD, Global Lead, 1HOPE-TDR glueddeke@aol.com

*Dr. Lueddeke is a member of the Advisory Board – One Health Initiative

By Professor Rohini R. Roopnarine, DVM, M. Phil, EdD, Dipl. AVOHS (Hon.), MRCVS

Member, National Academies of Practice ( Vet. Med), Course Director,  Veterinary Epidemiology & Public Health, School of Veterinary Medicine, True Blue campus, St. George’s University, Grenada, WI, Phone: +1 (473) 444-4175 ext. 3678, Email: rroopnarine@sgu.edu

 “Bon Giorno distinguished PhD graduates and Professors in Medicinal chemistry. This conference and the COST One Health Drugs event, comes at a critical time when we are live in unpredictable times, facing emerging threats to global health from Zoonotic diseases. Zoonoses are defined as Diseases naturally transmitted between people & vertebrate non-human animals. or agents of animal origin such as SARS-CoV-2, the agent of COVID-19, Ebola & Highly Pathogenic Avian Influenza, now of huge concern in the US as we see cattle emerging as the latest reservoirs of HPAI. Global warming arising from climatic changes has led us to encounter health challenges of greater complexity , some resulting from expanding vector distribution and a concomitant rise in vector-borne diseases. 

 Interprofessional collaboration is key to implementing OH as a tool for intercepting threats posed to human & planetary health. For decades, the focus has been on human health. But the reality is, human health is inextricably linked to animal health and the environment. Mosquitoes (malaria), ticks (Babesia) , Snails (Schistosomiasis) & Sandflies (Leishmaniasis) and other vectors carrying pathogens do not respect borders.They thrive in a delicate ecosystem, and the drugs created to combat them can have unintended consequences through both their environmental impact as well as unregulated useage. 

Your role & responsibilities as medicinal chemists, in the development  of new drugs, uniquely places you in a pivotal position in the global One Health agenda.

 The presentation today looks at…..title”

SEE: RR June 18 Rome PPT.pptx – Google 

________________________

Commentary: 

Prof. Rohini Roopnarine gave an inspirational lecture on June 18^th at the Paul Ehrlich&COST Action in Rome (https://medchem2024.help) to an audience of young researchers (PhD students) and academics with medicinal chemistry expertise. An educational view of the One Health concept and much more than this. How to dialogue with medicinal chemists in the One Health context? She could perfectly fit the purpose of the communication needs with the medicinal chemistry, a difficult task, and a non-obvious target. Under this light, Prof.Rohini made a successful effort to show real world examples of what an antiparasitic drug such as Ivermectin (active against different kinds of parasites to cure both humans and animal infections) can cause when overused and spread in the environment. The antimicrobials misuse implications in drug resistance development and those organizations and quadripartite alliance to manage the past disasters and the future events were clearly presented.  If I mention how the audience was captured by Rohini’s energy, it will not be enough. I only say about the enthusiastic comments and invitations received to bring her message to new events and future activities. Congratulations Rohini and thank you for accepting our invitation and being part of our OneHealthdrugs network!

Prof. Maria Paola Costi, PhD (Chair), Drug Discovery and Biotechnology Lab, Department of Life Science, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy, Office: +390592058579, Mobile: +393396559131

Craig N. Carter, DVM, MS, PhD is a member of the One Health Initiative Autonomous pro bono Team and the American Veterinary One Health Society (AVOHS) Board