One Health Publications

“This International Mother Earth Day, let’s celebrate the interconnectedness of all living things. The One Health approach embodies this very spirit, recognizing the profound link between the health of humans, animals, and our shared environment. …”

The pandemic treaty negotiations may fail – if so, what can we constructively build upon that so far has been achieved and even improve upon

“ … This could be a better way to engage core constituencies in pandemic prevention, preparedness and response. It also would integrate human, animal, plant and environmental health, One Health, as an important element of its mandate. …”

“… Further strengthen a One Health approach to GHS, including integrating infectious disease data from human, animal, plant and environment sectors; …”

Welcome Welcome The Organizing Committee cordially invites you to participate at MedChem 2024 (XIII Meeting of the Paul Ehrlich Euro-PhD Network) to be held in Rome from the 17th to the 19th of June 2024 in conjunction with COST Action Workshop One Health approach to tackle neglected infectious diseases challenges. As part of the COST Action workshop Young Researchers and Innovators will be engaged in the presentation of their research work in the field of neglected infectious diseases: Trypanosomiasis, Leishmaniosis, Schistosomiasis, Malaria and others in the field of medicinal chemistry/green chemistry and ecotoxicology. Designing lower environmental impact drugs. The MedChem2024 will be hosted by the Department of Chemistry and Technologies of Drugs, Sapienza University of Rome (Building CU019).   The venue for the meeting will be the room ‘La Ginestra’ in the Stanislao Cannizzaro Building (CU014) and the room “Raffaele Giuliano in the Chemistry and Technologies of Drugs Building, both located in the Sapienza Campus. The MedChem2024 is organized over three days, each one opened with a Plenary Lecture.   All  kinds of communications in the area of Medicinal Chemistry can be submitted. One section will be dedicated to the COST Action OneHealthdrugs Workshop: “One Health approach to tackle neglected infectious diseases challenges.” (One Health Drugs). During the workshop young Researchers and Innovators will be engaged in the presentation of their research work in the field of neglected infectious diseases: Trypanosomiasis, Leishmaniosis, Schistosomiasis, Malaria and others in the field of medicinal chemistry/green chemistry and ecotoxicology. Designing lower environmental impact drugs.   The Introduction lecture will be held by prof. ROHINI R. ROOPNARINE   Oral communications (15 minutes) and poster sessions are scheduled every day. The poster session will have two parts: a Flash Presentation of a 2 minutes short version of the poster in front of all the delegates in the Conference Room followed by a classical Poster session during the coffee breaks. There is availability for 34 posters.   Wednesday morning session will include the presentations of the awardees of the Paul Ehrlich MedChem Euro-PhD Certificate and awards ceremony.   A social dinner will been organized for the night of Tuesday 18th.   The number of participants is limited to 170. Save the dates in your calendar, Rome is waiting for you! Department of Chemistry and Technology of Drugs La Sapienza University of Rome – 17-19 June 2024 Rome, ITALY Paul Ehrlich Euro-PhD Network & OneHealthdrugs COST Action – IN PRESENCE MEETING

Also please see … OHD website in the announcement section:  https://www.onehealthdrugs.com/events/scientific-meeting/ and the OneHealthdrugs website:  https://www.onehealthdrugs.com

Opinion  Open access  Published: 12 April 2024

Abstract

Background

Despite the increasing focus on strengthening One Health capacity building on global level, challenges remain in devising and implementing real-world interventions particularly in the Asia-Pacific region. Recognizing these gaps, the One Health Action Commission (OHAC) was established as an academic community for One Health action with an emphasis on research agenda setting to identify actions for highest impact.

Main text

This viewpoint describes the agenda of, and motivation for, the recently formed OHAC. Recognizing the urgent need for evidence to support the formulation of necessary action plans, OHAC advocates the adoption of both bottom-up and top-down approaches to identify the current gaps in combating zoonoses, antimicrobial resistance, addressing food safety, and to enhance capacity building for context-sensitive One Health implementation.

Conclusions

By promoting broader engagement and connection of multidisciplinary stakeholders, OHAC envisions a collaborative global platform for the generation of innovative One Health knowledge, distilled practical experience and actionable policy advice, guided by strong ethical principles of One Health. 

“… Mitigation measures

Risk mitigation measures included in the One Health approach suggested surveillance among target animal and human populations along with the generation and sharing of genomic data. Target animals included wild and captive birds, poultry, susceptible domestic mammals such as fur animals, cats, pigs, and peri-domestic and peri-urban mammals.

The measures also comprised development and access to sustainable, rapid diagnostic methods using genomic data to screen for avian influenza virus in relevant populations. An additional critical area for risk mitigation was occupational safety in areas where humans interact closely with target animals. Furthermore, reassortment risk can be reduced by vaccinating individuals with a higher probability of occupational exposure to avian influenza against the seasonal influenza virus.

The scientific report also discussed other areas, such as improving the veterinary infrastructure, biosecurity, communicating the risk to various audiences, and vaccinating animals, which could help mitigate the risk of the avian influenza virus adapting to humans and animals. …”

“… “We are in fairly unprecedented, uncharted territory, globally in relationship to avian influenza,” says Dr. Peter Rabinowitz, director of the UW Center for One Health Research.

But federal officials and scientists stress the risk to the public still remains low. …”

“One Health Strategy

EPA promotes a “One Health” strategy, a holistic approach with the goal of achieving optimum health outcomes across the shared environment of people, plants, and animals. Over the last 20 years, EPA has supported the One Health approach through many different efforts including environmental research on metal and carbon engineered nanomaterials (ENMs), nanopesticides, 3-D printer emissions, nanoplastics, quantum dots (semiconductor nanocrystals), and epoxy-based nanomaterials. EPA research looks at where these materials go and what happens to them along the way, also referred to as fate and transport. EPA research on how people and the environment are exposed to nanomaterials, as well as their toxicity, has resulted in more than 500 peer reviewed publications. This research has advanced our understanding of nanomaterials in the environment, fully embracing the “One Environment” component of One Health as recommended in the 2023 National Academies of Sciences, Engineering, and Medicine Report.”

“Risk reduction

Authorities from different fields should work together with a One Health perspective to limit the exposure of mammals, including humans, to AI viruses. Animal and human surveillance should be enhanced, together with genomic analysis and sharing of sequence data. At farms, biosecurity should be strengthened to prevent animals coming into contact with the infection and spreading it.”

Promotes ‘One Health’ approach to engage frontline communities

“Kampala, Uganda | RONALD MUSOKE  | Uganda has embraced the ‘One Health’ approach in order to be able to predict, prepare and effectively respond to public health challenges.

Clovice Kankya, an Associate Professor at Makerere University says the “One Health approach” entails collaboration of multiple disciplines working locally, nationally, and globally, to attain optional health for people, animals, and the environment. …I know that human beings often take precedence in whatever programmes we come up with but we need to really advocate for the role the environment plays in the One Health approach because if we don’t prevent, we are bound to get more of what we are experiencing right now.”

Save the Dates: April 21 – 23, 2024

“Dr. Samira Mubareka, infectious disease physician, medical microbiologist and scientist at Sunnybrook, has received an Applied Public Health Chair, co-funded by the Canadian Institutes of Health Research (CIHR) and the Public Health Agency of Canada (PHAC). …”

“… The focus of Dr. Mubareka’s Chair is to use a One Health approach that examines the interconnections between humans, animals and their environment in order to develop adaptive and innovative approaches to prevent zoonotic pathogen spillover between species. This builds on collaborative research with wildlife disease ecologists, computational biologists, epidemiologists, virologists, and many other colleagues in human and animal health.

The honour highlights Dr. Mubareka’s ongoing leadership in One Health, pandemic response, and surveillance of viral zoonoses like SARS-CoV-2. In the past few years, she has chaired the Royal Society of Canada’s COVID-19 Task Force’s One Health Working Group, and collaboratively co-founded a multidisciplinary research collective, the Wildlife Emerging Pathogen Initiative (Wild EPI). In the early days of the COVID-19 pandemic, Dr. Mubareka and colleagues isolated the SARS-CoV-2 virus in a Level 3 containment facility, which helped researchers in Canada develop better diagnostic testing, treatments and vaccines and gain a better understanding of SARS-CoV-2 biology. Dr. Mubareka will continue working with the Royal Society of Canada and other key partners on knowledge mobilization around One Health.  …”

“… Dr. Mazet’s spoke to ODU students and faculty at her first lecture. The topic of her talk was on “Using One Health to Rank the Risk of Spillovers & Pandemic Potential for Novel Viruses.” Her talk centered around utilizing a One Health approach to emerging health threats including newly appeared or previously viral diseases that are increasing in incidence. She gave examples of various activities that occurred during the COVID-19 global pandemic but concluded with the observation that we have changed nothing to prevent or address things that could be applied to the next pandemic. Students and faculty asked questions at the completion of her talk and Dr. Mazet carefully and thoughtfully answered each and every question posed. Throughout the course of her visit on campus, Dr. Mazet also met with many graduate students. “She provided some excellent mentoring during her talks with the many graduate students interested in One Health in the Department,” said Holly Gaff, chair of ODU’s Department of Biological Sciences. …”