One Health Publications

Volume 11, No. 7, July 30, 2024

“Background

FAO promotes the application of the One Health approach as part of the transformation of the agri-food system for the benefit of human, animal, plant and environmental health. This involves a wide range of actors and work related to sustainable agriculture, animal, plant, forest and aquaculture health, food safety, antimicrobial resistance (AMR), nutrition and livelihoods.

Ensuring a One Health approach is essential to make progress in predicting, preventing, detecting and responding to diseases that spread between animals and humans, including antimicrobial resistance (AMR) and food safety, as well as managing environmental determinants of risks to human and animal health, within a set of interlinked disease causation challenges. The adoption of a One Health approach is also fundamental to the achievement of the Sustainable Development Goals (SDGs). …”

From P4 medicine to one health: a comprehensive approach to health and well-being

“… The FDA and other governments’ regulatory agencies are also collaborating in the One Health Initiative. The One Health Initiative is a movement to forge co-equal, all-inclusive collaborations between physicians, osteopathic physicians, veterinarians, dentists, nurses, and other scientific-health and environmentally related disciplines, including the American Medical Association, American Veterinary Medical Association, American Academy of Pediatrics, American Nurses Association, American Association of Public Health Physicians, the American Society of Tropical Medicine and Hygiene, the Centers for Disease Control and Prevention (CDC), the United States Department of Agriculture (USDA), and the U.S. National Environmental Health Association (NEHA).

The health of people, animals, and the environment is intertwined. A health hazard for people may likely be a health hazard for animals. Medical advances in understanding and treating a disease in one species, such as heart disease in people, may be applied to other species. A change in the environment can affect all living things, from people to animals to plants. For example, the Covid-19 pandemic was probably caused by people encroaching on new habitats and bringing bats that were infected with the SARS-CoV-2 virus into the open air market in Hunan, China. As humans continue to encroach on previously sparsely inhabited ecosystems, new zoonotic viruses may emerge.

The One Health Initiative recognizes this inter-connectedness and advocates a comprehensive approach to health and environmental problems versus a piecemeal approach. By building bridges between physicians, veterinarians, environmental scientists, and public health professionals, the initiative aims to “promote, improve, and defend the health and well-being of all species.

We are all in this together. For humanity to survive, we must do a better job of working together to solve the problems we all face from global climate change and other threats to public health. There is a group called the International Society for the Systems Sciences (ISSS) that is supporting this effort ¹⁰. It is a global community connected through systems theory, science and practice. The ISSS is a community of researchers, learners, and practitioners who are devoted to transdisciplinary inquiry into the nature of complex systems and the application of systems approaches for transformative change.”

Journal of Global, Public and One Health – Focusing on the survival of planet earth in Website: www.jgpoh.com

Corresponding author: Prof. Dr. med. Ulrich Laaser DTM&H, MPH: Faculty of Health Sciences, School of Public Health, Bielefeld-University, Bielefeld, Germany; Email: ulrich.laaser@uni-bielefeld.de

“Clemson University’s College of Veterinary Medicine (CVM) is on a mission to produce highly skilled and caring veterinarians to serve various roles in the work force. From small and large animal clinicians to those working with zoos and exotic animal species, CVM veterinarians’ expertise and interests will run the gamut. Some key areas of the profession are the high-demand fields like public health and regulatory services.

“We want to expose students to all of the amazing opportunities that exist in the world of public health, public service and research,” said CVM Founding Dean Steven Marks. “To fill this need, the CVM is making connections and building relationships with key stakeholders now.” …”

“… During the event, PAHO Director, Jarbas Barbosa, and Atul Gawande, USAID Assistant Administrator for Global Health engaged in a high-level dialogue to discuss the lessons learned from the COVID-19 pandemic, the interrelation between health, economic, and climate security, the rise in cases of bird flu and the importance of a One Health approach, as well as priority areas of collaboration moving forward. …”

“Abstract

Aim: The United Nations SDG (Sustainable Development Goals) database, inaugurated in 2015, contains extensive and considerable information to follow up on the progress of the SDGs. We shall, therefore, explore in this paper whether the exclusive use of the easily accessible SDG database and a limited selection of 17 suitable indicators, i.e., one indicator per Goal, allows for a stable analysis of progress. We aim to provide a methodology for easy use at the sub-national level on the initiative of non-governmental organizations and communities evaluating their activities towards One Health implementation.  …

… Conclusion: Progress towards the target year 2030 is too slow despite the growing knowledge that most world regions’ current economic, social, and environmental trajectories are unsustainable. A new tri- or four-partite global agency which has new representation from civil society could address many of the problems identified by paving the ways for bottom-up commitment, starting from monitoring achievements of the SDGs at the local level. The SOHI-Index can fulfil its intended purpose to support bottom-up commitment, requiring only one measurable indicator per SDG but no experts and no weighting of the selected indicators.”

Also, please see Laaser-U-et-al.-SOHI-Cover-note.pdf (jgpoh.com)

This work is published in Nature Communications in the paper, “A One Health framework for exploring zoonotic interactions demonstrated through a case study.”

Abstract  Background

In recent years, Babesia and Bartonella species co-infections in patients with chronic, nonspecific illnesses have continued to challenge and change the collective medical understanding of “individual pathogen” vector-borne infectious disease dynamics, pathogenesis and epidemiology. The objective of this case series is to provide additional molecular documentation of Babesia odocoilei infection in humans in the Americas and to emphasize the potential for co-infection with a Bartonella species.

Conclusions

We conclude that infection with Babesia odocoilei is more frequent than previously documented and can occur in association with co-infection with Bartonella spp.

Note: U.S. Centers for Disease Control and Prevention (CDC) https://www.cdc.gov/dpdx/babesiosis/index.html

SEE: OneHealthDrugs Workshop: “One Health approach to tackle infectious diseases challenges” at Paul Ehrlich&COST Action in Rome, Italy … June 17 – 19, 2024 – One Health Initiative

https://onehealthinitiative.com/onehealthdrugs-workshop-one-health-approach-to-tackle-infectious-diseases-challenges-at-paul-ehrlichcost-action-in-rome-italy-june-17-19-2024/

COST Action Blog: Uniting forces for Neglected Tropical Diseases

*One Health in Action: Interprofessional collaboration & Education to eliminate Neglected Tropical Diseases (NTDs)& Antimicrobial Resistance (AMR) –June 18, 2024

*By Professor Rohini R. Roopnarine, DVM, M. Phil, EdD, Dipl. AVOHS (Hon.), MRCVS

Member, National Academies of Practice ( Vet. Med), Course Director,  Veterinary Epidemiology & Public Health, School of Veterinary Medicine, True Blue campus, St. George’s University, Grenada, WI, Phone: +1 (473) 444-4175 ext. 3678, Email: rroopnarine@sgu.edu

 “Bon Giorno distinguished PhD graduates and Professors in Medicinal chemistry. This conference and the COST One Health Drugs event, comes at a critical time when we are live in unpredictable times, facing emerging threats to global health from Zoonotic diseases. Zoonoses are defined as Diseases naturally transmitted between people & vertebrate non-human animals. or agents of animal origin such as SARS-CoV-2, the agent of COVID-19, Ebola & Highly Pathogenic Avian Influenza, now of huge concern in the US as we see cattle emerging as the latest reservoirs of HPAI. Global warming arising from climatic changes has led us to encounter health challenges of greater complexity , some resulting from expanding vector distribution and a concomitant rise in vector-borne diseases 

 Interprofessional collaboration is key to implementing OH as a tool for intercepting threats posed to human & planetary health. For decades, the focus has been on human health. But the reality is, human health is inextricably linked to animal health and the environment. Mosquitoes (malaria), ticks (Babesia) , Snails (Schistosomiasis) & Sandflies (Leishmaniasis) and other vectors carrying pathogens do not respect borders.They thrive in a delicate ecosystem, and the drugs created to combat them can have unintended consequences through both their environmental impact as well as unregulated useage. 

Your role & responsibilities as medicinal chemists, in the development  of new drugs, uniquely places you in a pivotal position in the global One Health agenda.

 The presentation today looks at…..title”

SEE: RR June 18 Rome PPT.pptx – Google Slides https://docs.google.com/presentation/d/1PME4zioYBXn9OXrrD9u_OTDmDKtROhyZ/edit#slide=id.p1

________________________

Commentary: 

Prof. Rohini Roopnarine gave an inspirational lecture on June 18^th at the Paul Ehrlich&COST Action in Rome (https://medchem2024.help) to an audience of young researchers (PhD students) and academics with medicinal chemistry expertise. An educational view of the One Health concept and much more than this. How to dialogue with medicinal chemists in the One Health context? She could perfectly fit the purpose of the communication needs with the medicinal chemistry, a difficult task, and a non-obvious target. Under this light, Prof.Rohini made a successful effort to show real world examples of what an antiparasitic drug such as Ivermectin (active against different kinds of parasites to cure both humans and animal infections) can cause when overused and spread in the environment. The antimicrobials misuse implications in drug resistance development and those organizations and quadripartite alliance to manage the past disasters and the future events were clearly presented.  If I mention how the audience was captured by Rohini’s energy, it will not be enough. I only say about the enthusiastic comments and invitations received to bring her message to new events and future activities. Congratulations Rohini and thank you for accepting our invitation and being part of our OneHealthdrugs network!

Newly Released Audio-Video

https://drive.google.com/file/d/1uZTACQjLL9btIW1Pi_85pKLUIDx9122T/view?ts=66943226

Provided by:

Prof. Maria Paola Costi, PhD, Drug Discovery and Biotechnology Lab, Department of Life Science, University of Modena and Reggio Emilia, Via Campi 103, 41125, Modena, Italy, Office: +390592058579, Mobile: +393396559131

Dr. Costi is Chair COST (European Cooperation in Science and Technology): a funding agency for research and innovation networks. The COST ACTIONS help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation.

Prepared by Craig N. Carter, DVM, PhD

Member One Health Initiative Autonomous pro bono Team:

Laura H. Kahn, MD, MPH, MPP ▪ Bruce Kaplan, DVM ▪ Thomas P. Monath, MD ▪ *Lisa A. Conti, DVM, MPH ▪ Thomas M. Yuill, PhD ▪ Helena J. Chapman, MD, MPH, PhD ▪ Craig N. Carter, DVM, PhD ▪ Becky Barrentine, MBA ▪ Richard Seifman, JD, MBA   *Deceased November 6, 2020