One Health Publications

by *Richard Seifman, JD, MBA   June 30, 2022  in Health, Politics & Foreign Affairs

Ukraine is the latest example of the damage caused by war on human health, animals and the environment; external partners can help reduce losses

“Mental Health and One Health, the latter being the interface of human/animal/ecosystem health, address largely different scientific research, methods, public awareness and actions. Yet both face unanticipated challenges as a result of the Russian invasion, putting much greater burdens on an already overwhelmed Ukraine Government. External allies and donors can direct some of their human and financial resources to these non-military needs. Doing so will have multiple benefits, including helping to move Ukraine’s candidacy for European Union membership one step further.

Why should we address these two subjects together? What mental health and One Health have in common are supportive pronouncements by experts and public authorities, limited numbers of fully trained practitioners, and insufficient funding to do what is needed and known effective in crisis situations. Typically, neither are attentive to the other’s pursuits, scientific issues, and responses. This is partly because the disciplines have very different professional education and interests, and operational focus. But in this conflict situation, there are commonalities.  …”

 *Member, One Health Initiative team Advisory Board.

“In the wake of the COVID pandemic, and with the race against antibiotic resistance becoming ever more pressing, it is more important than ever to make the ‘One Health’ approach a reality.

The idea is to create a collaborative, cross-cutting approach which recognises the interconnections between people, animals, plants, and their shared environment with a view to achieving optimal health and well-being outcomes.

In this Event Report, EURACTIV explores how this concept can go from words to action and what role healthy animals play for One Health, in terms of producing safe and sustainable food but also in preventing outbreaks of diseases and their transmission between other animals or people.  …”

“ … The One Health concept is a global strategy to study the relationship between human, animal, and environmental health. The exchange of pathogenic and non-pathogenic microorganisms among these settings, associating the interconnection between humans, animals, and the environment, has been the main focus of one health study¹⁰.  …”

Lemos, L.N., de Carvalho, F.M., Santos, F.F. et al. Large Scale Genome-Centric Metagenomic Data from the Gut Microbiome of Food-Producing Animals and Humans. Sci Data 9, 366 (2022). https://doi.org/10.1038/s41597-022-01465-5

“ … Eng Fahd Al-Jalajel, the Saudi Minister of Health, recently emphasised the importance of bolstering global health systems and improving coordination through the implementation of the “One Health” approach. …”

Promoted by UNIVERSITY OF NICOSIA MEDICAL SCHOOL

“ … UNIC Vet School further encourages multidisciplinary excellence by encouraging its DVM cohort to study closely and conduct research with other medical and health students at UNIC. This level of collaboration ensures the programme truly enhances the holistic concept of One Health.

“The close synergies between the School of Veterinary Medicine, the Medical School and other health-related departments at UNIC create exciting research and interprofessional learning opportunities for our students,” confirms Professor Malas. “We are at the forefront of offering holistic veterinary medicine that meets the collective health and safety needs of the modern world. This approach to global public health education is unparalleled.”  …”

Press release

From Department of Health;  Department of Agriculture, Food and the Marine

Published on 23 June 2022

Last updated on 23 June 2022

One Health Initiative [website] Editor’s Note: Also see dynamic extensive recognition of the criticality of institutionalizing the One Health concept/approach worldwide by many visionary One Health Impakter articles!

RIYADH, 1 days ago

“Saudi Arabia has announced its support to G20’s working group on the global pandemic Preparedness Prevention and Response (PPR), and the need to ensure sustainable funding to combat global health security threats.

Saudi Health Minister Eng Fahd Al-Jalajel stressed the need to strengthen global health systems and enhance coordination through the ‘One Health’ approach. 

 This came during his speech delivered virtually on June 20, to the meeting of G20 health ministers held in Jakarta. …”

CAPT Brianna Skinner, DVM, MPH, DACLAM
Senior Regulatory Veterinarian
Office of Counterterrorism and Emerging Threats (OCET)
Food & Drug Administration (FDA)

Annamaria Castiglia, DVM
One Health Coordinator
Center of Veterinary Medicine (CVM)
Food and Drug Administration (FDA)

CAPT Brianna Skinner is a Commissioned Corps Officer in the U.S. Public Health Service currently assigned to the Office of Counterterrorism and Emerging Threats (OCET) at the U.S. Food and Drug Administration (FDA) as a Senior Regulatory Veterinarian.  She serves as a co-lead for the operations of FDA’s One Health Steering Committee, as senior staff advisor for FDA’s Animal Welfare Council and as an animal model expert for the administration of policies to facilitate the availability of safe and effective medical countermeasures in OCET. Prior to transferring to the FDA, she worked at the Centers for Disease Control and Prevention leading clinical operations within the vivarium and consulting with principal investigators on animal care and use with infectious disease research. She earned her Doctor of Veterinary Medicine degree from Tuskegee University, her Master’s in Public Health from Benedictine University, and is board certified in laboratory animal medicine with the American College of Laboratory Animal Medicine.

Dr. Annamaria Castiglia is a Veterinary Medical Officer currently working for the Center of Veterinary Medicine (CVM) in the Office of the Director as the CVM One Health Coordinator. Prior to her position at FDA, she worked in Small Animal Practice and the Animal Health Industry both domestically and internationally. In 1999, she was relocated by Hoffman La Roche-Animal Health to Washington, D.C. to represent them on Capitol Hill. During that year she completed her Lobbying Training Programs in Washington, D.C. In 2005-2019, she joined the One Health Academy as the coordinator in Washington, D.C. and was a member of the One Health Academy Board of Directors. She earned her Doctor of Veterinary Medicine degree from Bologna University, in Bologna Italy. She also completed the following post graduate programs: small animal medicine at the Animal Medical Center, New York City, New York; food animal medicine at the University of Pennsylvania Veterinary College, and swine health and management at Michigan State University and Iowa State University.

About the Presentation

The One Health concept works at the interconnection of three domains:  human, animal, and environmental health. One Health presents a more holistic view of the U.S. Food and Drug Administration’s (FDA) mission. The FDA’s efforts to improve health go beyond recognizing disease transmission through an isolated lens of human health and acknowledge human-animal interactions and associated environmental factors. The One Health concept’s convergence already exists in the FDA’s mission statement when considering the Agency’s responsibilities and authorities. The Agency fulfills its mission to benefit both people and animals by ensuring the safety and efficacy of regulated products such as food or feed, drugs, devices, and human biologics. It regulates the manufacturing, marketing, and distribution of regulated products to ensure that safety and quality standards are met that benefit both people and animals. The Agency utilizes a multidisciplinary and multisectoral approach to gathering data that enhances more informed, evidence-based regulatory decisions when establishing standards and guidance. Last but not least, FDA coordinates regulatory pathway measures fostering the advancement of medical countermeasures that diagnose, prevent, protect, and treat conditions derived from intentional or unintentional emerging threats for chemical, biological, radiological, or nuclear materials. These threats hold no boundaries and can adversely impact people and animals alike. This presentation will describe the One Health concept and how it applies to FDA’s regulatory mission. It will also explain FDA’s application of the One Health concept in its regulatory activities.

Learning Objectives

1. Describe the One Health concept.
2. Examine how FDA applies the One Health concept in its activities.
3. Explain how FDA’s application of the One Health concept has national and international reach.
4. Discuss some One Health challenges.
5. Explore what the future may look like as FDA adopts a One Health approach.

To Register

FDA employees must register in both LMS and Webcast. After Webcast registration, you will receive a link via email to access the live webinar. You must log in with the username and password created when you registered. Please pre-register at least two days before the event to ensure you receive the access link and outlook invitation for the session.

If you are not an FDA employee, register for the webcast only by clicking the Webcast Registration hyperlink below and then follow the instructions on the registration page.

1. LMS Registration *FDA Employees only.
2. Webcast RegistrationExternal Link Disclaimer *All participants MUST register for webcast to view FDA Grand Rounds!

For technical assistance please contact: Madison.Hanson@fda.hhs.gov

www.FDA.gov/GrandRounds

One Health

Various wild mammals have been identified as susceptible to monkeypox virus in areas that have long experienced monkeypox. These include rope squirrels, tree squirrels, Gambian pouched rats, dormice, non-human primates, among others. Some species may have asymptomatic infection. Other species, such as monkeys and great apes, show skin rashes typical of those found in humans. Thus far, there is no documented evidence of domestic animals or livestock being affected by monkeypox virus. There is also no documented evidence of human-to-animal transmission of monkeypox. However, there remains a hypothetical risk of human-to-animal transmission; as such appropriate measures such as physical distancing of persons with monkeypox from domestic pets, proper waste management to prevent the disease from being transmitted from infected humans to susceptible animals at home (including pets), in zoos and wildlife reserves, and to peri-domestic animals, especially rodents.

As future pandemics are likely to emerge from the coronavirus family of viruses and other zoonotic pathogens, an integrated approach to develop vaccines for zoonotic diseases is essential for success

June 18, 2022

by Craig Carter, DVM, PhD, Thomas Monath, MD and Rohini Roopnarine

in Health, Society

“ …  Broadening the field of One Health

Ramirez has watched—and helped shape—changes in how the field of One Health works.

Now, there’s less “helicopter research,” with scientists dropping in to conduct field studies and never reporting back to the community with the findings, she said.

Instead, “we’re doing a lot of capacity-building where we’re helping young scientists increase their abilities to address emerging needs and interviewing indigenous knowledge-keepers and scientists to learn how they approach One Health,” she said.

Her next project: Seeking larger, more sustainable funding sources to continue to grow COHR and the One Health Clinic in response to demand.

In a way, the COVID-19 pandemic is helping her make the case. “Now, everybody knows what zoonotic disease is, and there’s a lot of interest in emerging infectious diseases. I’m hoping that will bring more funders to this research,” she said.”

“In this study, our findings firstly demonstrate that P. yoelii 17XNL infection had significant anti-colon cancer effects in mice by inhibiting tumor cell proliferation and promoting mitochondrial apoptosis, which may relate to the inhibition of mitochondrial biogenesis and mitophagy. The results presented here may inspire a new approach for the treatment of colon cancer.”

“… “The challenge is to take an integrated and unified approach to these problems right through from agriculture and the environment to food production and human health, in what’s termed a One Health approach. To do that we need to collaborate with food and other associated industries to share research and innovation and deliver training activities.” …”