One Health Publications

Advancing Health Care in Humans, Animals and the Environment

“… One Health is more than a call to personal action—it’s a collaborative solution to complex challenges. By connecting people, animals and the environment, the initiative is laying the foundation for a stronger, more resilient Kentucky.   …”

By *One Health Initiative Autonomous pro bono Team:

Laura H. Kahn, MD, MPH, MPP  Bruce Kaplan, DVM  Thomas P. Monath, MD  Thomas M. Yuill, PhD  Helen J. Chapman, MD, MPH, PhD  Craig N. Carter, DVM, PhD  Becky Barrentine, MBA  Richard Seifman, JD, MBA

‘One Medicine−One Health’: An Historic Perspective by One Health Initiative team, Pages 18 -27.  Contained in: Official Journal of The World Medical Association, Inc. Nr. 2, June 2023, Vol. 69

Volume 12, No. , Released October 25, 2025

Sharing news gathered during September and October 2025

Countdown for the

10th Annual

One Health Day

2025

November 3 marks 10 Years of One Health Day Events Celebrating and Educating about One Health and One Health Issues!!

Abstract

One Health is a concept and framework for addressing the interconnected nature of humans, animals and their environments to improve the health and wellbeing of all three, along with added social and financial benefits. On a microscopic level, the microbiota is a clear biological connector with strains shared across domains (One Health Microbiome). In this review, we introduce the concept of One Health and the One Health Microbiome and discuss strain-sharing across and within domains. We also highlight its impact on the spread of antimicrobial resistance (AMR) genes as well as overall microbiome diversity and resilience to climate change. Finally, we discuss critical areas for further research and conceptual development, encouraging future research integrating One Health and microbiota-AMR concepts.

Highlights

• Environmental, animal and human microbiomes are connected, forming together the so-called “One Health Microbiome”.
• Within the One Health Microbiome, there is extensive sharing of strains, contributing to positive outcomes, such as buffering against stressors like climate change, and negative outcomes, such as sharing of pathogens and antimicrobial resistant strains.
• Strain-sharing follows ecological principles, including strain dispersion and environmental/host filtering.
• Strain-sharing is dependent on the taxonomic identity of the strain shared, its capacity to adapt to a new environment and the characteristics of the ecosystem into which it is transferred.
• Microbiomes, especially if they are in a dysbiotic state, are also hubs for the emergence and spread of AMR genes.

Muhummed, A.M., Lanker, K.C., Yersin, S. et al. One Health, One Microbiome. Microbiome 13, 216 (2025). https://doi.org/10.1186/s40168-025-02231-6

Policies devised and implemented by the U.S. Health and Human Services (HHS) Secretary are ironically detrimental and diametrically counter to President Donald J. Trump’s “Make America Healthy Again (MAHA)”

U.S. President Donald  J. Trump and HHS Secretary Robert F. Kennedy, Jr. speaking with attendees at an Arizona for Trump rally at Desert Diamond Arena in Glendale, Arizona, Aug. 23, 2024

“Friday’s layoffs swept up scientists involved in responding to disease outbreaks and running an influential journal. Officials said the mistaken dismissals were being rescinded.”