One Health Publications

Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand

March 18, 2020

16 March 2020 Imperial College COVID-19 Response Team  DOI: https://doi.org/10.25561/77482 Page 1 of 20   Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand     https://www.imperial.ac.uk/media/imperial-college/medicine/sph/ide/gida-fellowships/Imperial-College-COVID19-NPI-modelling-16-03-2020.pdf  Summary       The global impact of COVID-19 has been profound, and the public health threat it represents is the most serious seen in a respiratory virus since the 1918 H1N1 influenza pandemic. Here we present the results of epidemiological modelling which has informed policymaking in the UK and other countries in recent weeks. In the absence of a COVID-19 vaccine, we assess the potential role of a number of public health measures – so-called non-pharmaceutical interventions (NPIs) – aimed at reducing contact rates in the population and thereby reducing transmission of the virus. In the results presented here, we apply a previously published microsimulation model to two countries: the UK (Great Britain specifically) and the US. We conclude that the effectiveness of any one intervention in isolation is likely to be limited, requiring multiple interventions to be combined to have a substantial impact on transmission.  Two fundamental strategies are possible: (a) mitigation, which focuses on slowing but not necessarily stopping epidemic spread – reducing peak healthcare demand while protecting those most at risk of severe disease from infection, and (b) suppression, which aims to reverse epidemic growth, reducing case numbers to low levels and maintaining that situation indefinitely. Each policy has major challenges. We find that that optimal mitigation policies (combining home isolation of suspect cases, home quarantine of those living in the same household as suspect cases, and social distancing of the elderly and others at most risk of severe disease) might reduce peak healthcare demand by 2/3 and deaths by half. However, the resulting mitigated epidemic would still likely result in hundreds of thousands of deaths and health systems (most notably intensive care units) being overwhelmed many times over. For countries able to achieve it, this leaves suppression as the preferred policy option.    We show that in the UK and US context, suppression will minimally require a combination of social distancing of the entire population, home isolation of cases and household quarantine of their family members. This may need to be supplemented by school and university closures, though it should be recognised that such closures may have negative impacts on health systems due to increased absenteeism. The major challenge of suppression is that this type of intensive intervention package – or something equivalently effective at reducing transmission – will need to be maintained until a vaccine becomes available (potentially 18 months or more) – given that we predict that transmission will quickly rebound if interventions are relaxed. We show that intermittent social distancing – triggered by trends in disease surveillance – may allow interventions to be relaxed temporarily in relative short time windows, but measures will need to be reintroduced if or when case numbers rebound. Last, while experience in China and now South Korea show that suppression is possible in the short term, it remains to be seen whether it is possible long-term, and whether the social and economic costs of the interventions adopted thus far can be reduced.         gebelik hafta hafta gebelik kadın doğum kadın doğum uzmanı istanbul kadın doğum doktoru kadın doğum doktoru bahçelievler kadın doğum doktoru jinekolog kadın hastalıkları hamilelik belirtileri

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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

March 13, 2020

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study  Published Online, The Lancet March 9, 2020 https://doi.org/10.1016/ S0140-6736(20)30566-3    Summary Background Since December, 2019, Wuhan, China, has experienced an outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Epidemiological and clinical characteristics of patients with COVID-19 have been reported but risk factors for mortality and a detailed clinical course of illness, including viral shedding, have not been well described. See: https://www.thelancet.com/pb-assets/Lancet/pdfs/S014067362305663.pdf

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The effort to fight emerging infectious diseases must be holistic

March 10, 2020

The effort to fight emerging infectious diseases must be holistic The Hill Many scientists, scholars and practitioners working in the field of One Health, which promotes a holistic approach to environmental, animal, food and ... “... Fortunately we can draw upon insights from recent interdisciplinary initiatives. Many scientists, scholars and practitioners working in the field of One Health, which promotes a holistic approach to environmental, animal, food and human health, have advocated for a variety of policy and governance interventions. These strategies address trade and illegal harvest of wildlife, land use changes that promote the emergence of EIDs and the need for targeted global surveillance to identify novel pathogens. The Planetary Health Alliance is a consortium of universities, NGOs, research institutes and government entities around the world focused on understanding and addressing the health impacts of global environmental change. These and other groups have found strong evidence that disease regulation is an important ecosystem service that remains under appreciated by the public and decision-makers. This issue is likely to be a discussion point at upcoming international congresses like the Convention on Biological Diversity and the IUCN World Conservation Congress. ...” 

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HAND WASHING: how-to…

March 9, 2020

HAND WASHING how-to from U.S. Center Centers for Disease Control and Prevention (CDC) https://www.cdc.gov/handwashing/when-how-handwashing.html

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COVID-19…Current Coronavirus Updated Information

March 7, 2020

COVID-19...Current Coronavirus Updated Information https://www.cdc.gov/coronavirus/2019-ncov/index.html

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Welcome to the One Health APP

March 7, 2020

Welcome to the One Health APP     The One Health Assessment for Planning and Performance (OH-APP) is a monitoring framework for multisectoral coordination mechanisms (MCM) to annually self-assess their organizational capacity and performance to inform planning and development assistance. The OH-APP complements the WHO Joint External Evaluation by providing more specific indicators to measure the maturity of an MCM and benchmark its progress toward becoming a sustainable mechanism capable of coordinating multisectoral and multistakeholder collaboration for preparedness and response to public health threats. ...   Complete information, see https://www.onehealthapp.org/about

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Trust for Americas Health – Statement on COVID-19

March 3, 2020

  TFAH Statement on COVID-19 Preparations see: https://www.tfah.org/article/tfah-statement-on-covid-19-preparations/ 

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DUKE (USA) ONE HEALTH Newsletter – Issue 24 March 2020

March 2, 2020

ISSUE 24                                                                                            March 2020   https://mailchi.mp/fdf31575086e/oh-newsletter-march-issue

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One Health Happenings News Notes – February 2020

March 1, 2020

February 2020 One Health Happenings News Notes is prepared and shared by the One Health Commission     View archived issues : http://bit.ly/2IIhhc6  

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World Vaccine Congress – Washington, DC April 6-9, 2020

February 28, 2020

  R&D + Strategic Partnering For The Global Vaccine Industry Join us for the worlds most exciting vaccine event   Main Congress April 7-9 | Pre - Congress Workshops April 6 Walter E. Washington Convention Center View all speakers https://www.terrapinn.com/conference/world-vaccine-congress-washington/agenda.stm     Apr 7 15:20 The importance of a One Health approach to biodefense and biosecurity One Health   Michael Angelastro, Project Officer, U.S. Department of Health & Human Services Laura Kahn, Co-Founder, One Health Initiative Dorothy Peprah, Senior Global Health Security Agenda Advisor, United States Agency For International Development Prof Ab Osterhaus, Director, Research Center For Emerging Infections And Zoonoses (Riz), University of Veterinary Medicine Hannover Deborah Whitmer, Chief Of Staff, U.S. Army Medical Research and Development Command

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TEN PROPOSITIONS FOR GLOBAL SUSTAINABILITY [#7 = One Health approach]

February 26, 2020

BOX 12.1 : TEN PROPOSITIONS FOR GLOBAL SUSTAINABILITY        What if? *7. THE UNIFYING ONE HEALTH AND WELL-BEING CONCEPT became  the cornerstone of our education systems and societal institutions, thereby helping to create a more just, sustainable and peaceful world (UN-2030 Global Goals (SDGS). © 2019 George R. Lueddeke Source  Lueddeke, G.R. (2019). Survival: One Health, One Planet, One Future. Abingdon, Oxon / New York: Routledge https://www.amazon.com/Survival-Health-Routledge-Studies-Sustainability/dp/1138334952.  (Ch 12- Leading in an era of uncertainty, upheaval and  anxiety)

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Coronavirus being watched closely in Virginia by both public officials and students in a program at Ferrum College

February 25, 2020

    Martinsville, Virginia (USA) Coronavirus being watched closely in Virginia by both public officials and students in a program at Ferrum College   https://www.martinsvillebulletin.com/news/local/coronavirus-being-watched-closely-in-virginia-by-both-public-officials/article_ae22943e-917d-5432-a593-7606b8607b46.html              By Amie Knowles Special to the Bulletin “... Watching keenly developments of the new strain is a group of students at Ferrum College who are in the One Health program, which focuses on the intersection of human, animal and environmental health. The program also studies how illnesses affect the global economy and the political impact outbreaks like COVID-19 can have. Ferrum College began the One Health program in the fall of 2019, one of 10 such programs in the U.S., according to a 2016 study in the One Health Journal: Infection, Ecology and Epidemiology and a paper published in 2018. [https://nam.edu/core-competencies-in-one-health-education-what-are-we-missing/]   “One Health students begin by learning how human health is impacted by the interaction of the aspects of our world such as air, water, animals, plants, foods and soil. In order to prevent further outbreaks, we must understand how individual systems operate and the interconnections between those systems,” said Delia Heck, a professor of environmental science, natural science division chair and environmental science and environmental studies program coordinator at Ferrum. “One Health students study aspects such as disease pathways, pathogens, risk management, human systems, animal systems and soil, plant and animal-based food health. They then work in teams to determine solutions to problems that might arise within those systems. As part of their capstone project, they must focus on a particular One Health issue and write an in-depth research paper on it.” ... “

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February 24, 2020

  “We are at a turning point”: The coronavirus outbreak is looking more like a pandemic Vox “One cannot shut out the rest of the world.” ... If halting the spread of the virus is increasingly out of reach, public health officials will have to accept that ... https://www.vox.com/2020/2/23/21149327/coronavirus-pandemic-meaning-italy  

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An interdisciplinary approach to tackling coronavirus

February 23, 2020

  An interdisciplinary approach to tackling coronavirus University World News This was not the first voicing of One Health aspirations in Europe. The European Commission published an EU One Health Action Plan in 2017, but its ... Please read complete article at: https://www.universityworldnews.com/post.php?story=20200219125312563  

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February 23, 2020

The One Health concept -- the health of humans is intimately linked with the health of animals ... Wiley Online Library From the Division of Renal Medicine, Department of Clinical Science, Intervention and Technology Karolinska Institutet, Campus Flemingsberg, Stockholm, Sweden   One health. Content List – This is an article from the symposium: “Bioinspirational medicine”. Innovation based on bioinspiration, that is biomi-... https://onlinelibrary.wiley.com/doi/pdf/10.1111/joim.13015

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ONE HEALTH Organizations

February 22, 2020

One Health organizations   World Organisation for Animal Health EcoHealth Alliance Global Alliance for Rabies Control World Veterinary Association World Medical Association Swiss Tropical and Public Health Institute International Society for Infectious Diseases Chittagong Veterinary and Animal Sciences University    

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An Urgent Call to Make One Health Work for People and Our Planet

February 21, 2020

An Urgent Call to Make One Health Work for People and Our Planet MEDICC Review January 2020 begins a new decade, a chance for the international health community to take a hard look at where we are, where we stand, what we ...

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Trending Topics of One Health and Suicide Prevention Kickoff FREE Training for Veterinary Community

February 19, 2020

  Trending Topics of One Health and Suicide Prevention Kickoff FREE Training for Veterinary ... openPR (press release) Austin, Texas February 18, 2020 - The important topics of One Health and Suicide Prevention are both included in a new initiative to provide training to ... SEE: https://www.openpr.com/news/1936603/trending-topics-of-one-health-and-suicide-prevention-kickoff  

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World Veterinary Association (WVA) and Health for Animals announce the 2020 World Veterinary Day theme: Environmental protection for improving animal and human health

February 17, 2020

The World Veterinary Association (WVA) and Health for Animals are proud to announce the 2020 World Veterinary Day theme: Environmental protection for improving animal and human health. For 20 years, World Veterinary Day has been an opportunity to celebrate the contributions of veterinarians to the health of animals and society. As One Health advocates, veterinarians know that environmental, human and animal health are inextricably linked. Negative changes to our environment will ultimately harm ourselves and the animals in our care. The 2020 World Veterinary Day will be held on 25th April 2020 and is an opportunity to celebrate the work of veterinarians to protect our environment. The deadline for applications submission is 25th May 2020.  All the necessary information, application form and instructions, can be found in the attached documents.    The WVA encourages its partners to collaborate with WVA member associations and veterinarians around the world to celebrate the WVD2020 and to take part in the World Veterinary Day Award 2020.  Provided by: Dr Zeev Noga Executive Director   World Veterinary Association (WVA) Avenue de Tervueren 12 B-1040 Brussels, Belgium Tel: +32 (0) 2 533 70 22 zeev_noga@worldvet.org  secretariat@worldvet.org http://www.worldvet.org

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One Health concept gains importance

February 16, 2020

 Kerala One Health concept gains importance SEE FULL ARTICLE AT: ttps://www.thehindu.com/news/national/kerala/one-health-concept-gains-importance/article30832842.ece    Expert says programme can reduce incidence of zoonotic threats The concept of ‘One Health’, which recognises that health of human beings is connected to health of animals and environment, is gaining importance as most of the contagious diseases affecting humans are zoonotic (animal to man origin) in nature. “The concept of One Health can be effectively implemented for reducing incidence of emerging zoonotic threats like COVID-19. One Health is the collaborative efforts of multiple disciplines working locally, nationally, and globally, to attain optimal health for people, animals and our environment, as defined by the One Health Initiative Task Force,” says Dr. B. Sunil, Professor, Veterinary Public Health & Head, meat plant, Kerala veterinary and animal sciences university. ...

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