One Health Publications

“The One Health Section focuses on the linkages among humans, animals and the environment through the One Health concept. One Health promotes a framework for the holistic understanding of factors impacting our increasingly connected world. The One Health Section encourages team-oriented approaches to solve complex health problems based on the understanding that health across all sectors is interrelated. Our members come together to discuss ways to promote the optimal health of people, domestic animals, wildlife, plants and our environment.  …”

Abstract

COVID-19 is the latest zoonotic RNA virus epidemic of concern. Learning how it began and spread will help to determine how to reduce the risk of future events. We review major RNA virus outbreaks since 1967 to identify common features and opportunities to prevent emergence, including ancestral viral origins in birds, bats, and other mammals; animal reservoirs and intermediate hosts; and pathways for zoonotic spillover and community spread, leading to local, regional, or international outbreaks. The increasing scientific evidence concerning the origins of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is most consistent with a zoonotic origin and a spillover pathway from wildlife to people via wildlife farming and the wildlife trade. We apply what we know about these outbreaks to identify relevant, feasible, and implementable interventions. We identify three primary targets for pandemic prevention and preparedness: first, smart surveillance coupled with epidemiological risk assessment across wildlife–livestock–human (One Health) spillover interfaces; second, research to enhance pandemic preparedness and expedite development of vaccines and therapeutics; and third, strategies to reduce underlying drivers of spillover risk and spread and reduce the influence of misinformation. For all three, continued efforts to improve and integrate biosafety and biosecurity with the implementation of a One Health approach are essential. We discuss new models to address the challenges of creating an inclusive and effective governance structure, with the necessary stable funding for cross-disciplinary collaborative research. Finally, we offer recommendations for feasible actions to close the knowledge gaps across the One Health continuum and improve preparedness and response in the future.

For more information about One Health and what you can do to promote it, the One Health Initiative and the One Health Commission publish regular blogs and news. One Health Day – November 3rd – will see many organisations hosting articles and events to promote One Health. Look out for how you can get involved, or even how your work is already promoting One Health in some way…may be you are already a One Health Champion without even realising it!

Conclusions

The study of the etiopathogenesis, pathophysiology, genetics, and treatment of naturally occurring ocular disease in veterinary patients, especially dogs, cats, and horses, translates well to human eye disease because of similarities of ocular anatomy, physiology, and shared environments between animals and humans. These similarities support the collaborative, multisectoral, and transdisciplinary approach that defines the one health initiative. Veterinarians at all levels, therefore, are at the forefront of the one health process through their study of ocular disease, whether it is in their practice, clinic, university hospital, or research laboratory. We all share the one health goal of achieving optimal ocular health for all by recognizing the interconnection between people, animals, and their shared environment.

*Dr. Monath is a co-founding member of the One Health Initiative Autonomous pro bono Team: Laura H. Kahn, MD, MPH, MPP ▪ Bruce Kaplan, DVM ▪ Thomas P. Monath, MD ▪ *Lisa A. Conti, DVM, MPH ▪ Thomas M. Yuill, PhD ▪ Helena J. Chapman, MD, MPH, PhD ▪ Craig N. Carter, DVM, PhD ▪ Becky Barrentine, MBA ▪ Richard Seifman, JD, MBA  *Deceased November 6, 2020

** “One Health” mentioned at time 130.20 – 131.20.

“… Committed to improving the well-being of all

UC Davis Health uses an interdisciplinary approach, known as One Health, on issues surrounding global health. This vision of One Health recognizes the interconnectedness of people, animals, and the environment and aims to identify and address the fundamental causes of poor health to improve the well-being of all. …”

SEE: One Health: A Paradigm Whose Time Has Come? – Impakter — https://impakter.com/one-health-paradigm-time-come/

Finding common ground between countries and institutions to deal with our common health future is still an uphill road at the upcoming G20 in Indonesia

Abstract

Leptospirosis is an archetypal One Health problem as described in the companion Currents in One Health article in the October 2022 issue of the Journal of the American Veterinary Medical Association by Sykes et al. A thorough understanding of leptospirosis requires a detailed analysis of the elaborate interplay among pathogenic leptospiral strains, host species, and the environment. Such an understanding is required to inform appropriate preventative measures including vaccine design, prophylaxis efforts, educational programs that help to reduce exposure to pathogenic spirochetes, as well as policy development. Because of the complex epidemiology of leptospirosis, a One Health approach as defined by the One Health Initiative Task Force is critical—an approach that calls for “the collaborative efforts of multiple disciplines working locally, nationally, and globally, to attain optimal health for people, animals and our environment.” Over the last three decades, progressive advances in cutting-edge molecular typing techniques, as well as our ability to rapidly generate and share large amounts of sequence data through establishment and growth of databases, have been central to accelerating a One Health understanding of the epidemiology of leptospirosis. Nevertheless, our dependence on serotype information because of the serovar-specific nature of current vaccines means that laborious serotyping efforts continue. With the advent of new approaches such as mRNA vaccines that are based on lipopolysaccharide immunogens, sequence- and/or proteomics-based typing methods may replace these methods.

“This international rabies training aims to foster the emergence of collaborations between young professionals from different disciplines and sectors, and from diverse African countries. It is expected that these actors will contribute to the strengthening of the One Health approach in their respective countries to achieve the goal of zero human rabies cases by 2030.”

“… They conclude by suggesting that a One Health approach to preventing further zoonotic disease outbreaks could incorporate promoting alternatives to bushmeat, routinely vaccinating people at high risk of exposure and educating people in hygienic procedures such as the wearing of gloves when handling live and dead wild animals.”

“… A One Health approach

It is evident that antimicrobial resistant microbes surround us, and it is normal to feel concerned. But what is even more important to recognize are the tiny steps we all can still adopt. This includes ensuring patients are treated with the appropriate antibiotic in the right dose.

On a global level, understanding the transmission routes for resistant microbes is a part of a One Health approach. The holistic concept of One Health acknowledges that the health of humans is interconnected to the health of animals and our surrounding environment. This enables bringing together resources and policies to monitor and tackle antimicrobial resistance.

Indeed, resistant microbes are running a marathon with antimicrobials, and we need to take measures to slow down their pace. In the long run, this would ensure that the antimicrobials would continue to support human survival.  …”