This work was the master’s degree thesis research of the first author, Helena Turck, as part of a graduate program in One Health jointly run by …

A new World Bank/WHO Fund could treat prevention as a priority and for which the One Health interdisciplinary approach is critical   

By Laura H. Kahn, MD, MPH, MPP and Richard Seifman, JD, MBA

August 25, 2022  in Health, Politics & Foreign Affairs

“Veterinary Public Health in Los Angeles County, California, announced it received funding from the CDC and Council of State and Territorial Epidemiologists (CSTE) to support the county’s efforts of surveillance of SARS-CoV-2 in animals. Through this project, the county will be able to learn more about COVID-19 from a One Health view. The free testing will also help learn more about the significance of humans, animals, and environmental relationships regarding COVID-19.  …”

Zhou, N., Cheng, Z., Zhang, X. et al. Global antimicrobial resistance: a system-wide comprehensive investigation using the Global One Health Index. Infect Dis Poverty 11, 92 (2022). https://doi.org/10.1186/s40249-022-01016-5

Abstract

Background

Antimicrobial resistance (AMR) is one of the top ten global public health challenges. However, given the lack of a comprehensive assessment of worldwide AMR status, our objective is to develop a One Health-based system-wide evaluation tool on global AMR.

Provided by:

George Lueddeke (PhD)  (OHI  bio)

Adviser in Higher, Medical and One Health Education

Global Lead, International One Health for One Planet Education Initiative (1 HOPE)

Southampton, United Kingdom

*****

Publications

Planet Earth: Averting a Point of No Return?’

https://impakter.com/planet-earth-averting-point-no-ret‘urn/

Reflections on the Transformation of Higher Education in the 21^st Century

Part 1: The One Health & Wellbeing Concept

Part 2: Development of a Global ‘All Life’ narrative

Part 3: The international One Health for One Planet Education Initiative (1 HOPE) and the ‘ecological  university’

By **Richard Seifman, JD, MBA

**Member One Health Initiative Autonomous pro bono Team:

Laura H. Kahn, MD, MPH, MPP ▪ Bruce Kaplan, DVM ▪ Thomas P. Monath, MD ▪ *Lisa A. Conti, DVM, MPH ▪ Thomas M. Yuill, PhD ▪ Helena J. Chapman, MD, MPH, PhD ▪ Craig N. Carter, DVM, PhD ▪ Becky Barrentine, MBA ▪ Richard Seifman, JD, MBA

*Deceased November 6, 2020

“…The Tennessee Department of Agriculture’s Animal Health Division is responsible for promoting animal health in Tennessee. The state veterinarian’s office seeks to prevent the spread of disease through import and movement requirements, livestock traceability, disaster mitigation, and the services of the C.E. Kord Animal Health Diagnostic Laboratory. The division collaborates with other health-related stakeholders, academic institutions, and extension services to support One Health, an initiative to improve health for people and animals.”

Abstract

Efforts to mitigate the increasing emergence of antimicrobial resistance (AMR) will benefit from a One Health perspective, as over half of animal antimicrobials are also considered medically important in humans, and AMR can be maintained in the environment. This is especially pertinent to low- and middle-income countries and in community settings, where an estimated 80% of all antibiotics are used. This study features AMR genes found among humans, animals, and water at an urban informal settlement in Nepal with intensifying livestock production. We sampled humans, chickens, ducks, swine, and water clustered by household, as well as rodents and shrews near dwellings, concurrently in time in July 2017 in southeastern Kathmandu along the Manohara river. Real-time qualitative PCR was performed to screen for 88 genes. Our results characterize the animal-human-environmental interfaces related to the occurrence of specific resistance genes (bla_SHV-1 (SHV(238G240E) strain), QnrS, ermC, tetA, tetB, aacC2, aadA1) associated with antibiotics of global health importance that comprise several drug classes, including aminoglycosides, beta-lactams, tetracyclines, macrolides, and fluoroquinolones. By characterizing risk factors across AMR genes of public health importance, this research highlights potential transmission pathways for further investigation and provides prioritization of community-based prevention and intervention efforts for disrupting AMR transmission of critically important antibiotics used in both humans and animals in Nepal.

Background

Anthrax is a zoonotic disease that causes frequent outbreaks in livestock and fatal human cases in Burkina Faso. Effective surveillance of this disease calls for the establishment of an integrated surveillance system, in line with the One Health concept. However, despite a strong technical and financial support from international partners, surveillance is still poorly conducted within an integrated approach. Based on stakeholder perspectives, the study has for objective to deepen our understanding of the anthrax surveillance system and to identify the obstacles and levers towards a more integrated approach to anthrax surveillance in Burkina Faso.

by Frank A. von Hippel, PhD | Mel and Enid Zuckerman College of Public Health (arizona.edu)

Open Access Review

Abstract: Coccidioidomycosis is an endemic fungal infection that is reported in up to 20,000 persons per year and has an economic impact close to $1.5 billion. Natural infection virtually always confers protection from future exposure, and this suggests that a preventative vaccine strategy is likely to succeed. We here review progress toward that objective. There has been ongoing research to discover a coccidioidal vaccine over the past seven decades, including one phase III clinical trial, but for reasons of either efficacy or feasibility, a safe and effective vaccine has not yet been developed. This review first summarizes the past research to develop a coccidioidal vaccine. It then details the evidence that supports a live, gene-deletion vaccine candidate as suitable for further development as both a veterinary and a human clinical product. Finally, a plausible vaccine development plan is described which would be applicable to this vaccine candidate and also useful to other future candidates. The public health and economic impact of coccidioidomycosis fully justifies a public private partnership for vaccine development, and the development of a vaccine for this orphan disease will likely require some degree of public funding.

One Health Happenings: Sharing news July / Early August 2022

Study International

One Health recognises that the health of people is connected to the health of animals and the environment. This has been evident throughout the …

WHO | World Health Organization

… priorities including comprehensive field investigations that follow a One Health approach, and clinical management and treatment approaches.